Chronic Granulomatous Lymphadenitis

  • Roberto N. Miranda
  • Joseph D. Khoury
  • L. Jeffrey Medeiros
Part of the Atlas of Anatomic Pathology book series (AAP)


Chronic granulomatous lymphadenitis is a distinctive form of inflammatory immune response in which organized collections of epithelioid macrophages form granulomas. Lymph node involvement by chronic granulomatous inflammation is identified commonly in clinical practice. Various infectious and noninfectious etiologies have been associated with chronic granulomatous inflammation in lymph nodes. In broad terms, granulomatous inflammation ensues when a foreign agent cannot be eliminated by the immune system and is instead walled off by activated macrophages.


Lymph Node Clinical Practice Immune System Giant Cell Clinical Finding 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Roberto N. Miranda
    • 1
  • Joseph D. Khoury
    • 1
  • L. Jeffrey Medeiros
    • 1
  1. 1.Department of HematopathologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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