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Patient Empowerment: Consequences for Pharmaceutical Marketing and for the Patient–Physician Relationship

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Innovation and Marketing in the Pharmaceutical Industry

Part of the book series: International Series in Quantitative Marketing ((ISQM,volume 20))

Abstract

Big Pharma’s blockbuster model—which entails developing new drugs for diseases affecting a very large number of patients, promoting it to physicians as the new best-in-class treatment, and profiting from the ensuing volume of sales—is under threat. In the last 2 decades, the largest pharmaceutical firms have lost billions of dollars in shareholder value, due to a combination of factors such as declining R&D productivity, stricter regulatory requirements, more intense generic competition, and an increasingly ineffective marketing model. I review societal, demographic, regulatory, and technological trends and discuss how such trends are contributing to the rise of a new class of empowered patients. I discuss the implications of patient empowerment for the patient–physician relationship and for therapy launch and therapy promotion. Building on real-world evidence, I discuss the benefits and challenges of direct-to-patient marketing strategies such as nurturing partnerships with key patient opinion leaders and direct-to-patient communication via social media. Through a content analysis of the 2005–2010 annual reports of the largest 20 pharmaceutical firms, I show that, despite strict regulatory requirements, several firms have started to embrace patient empowerment as a key component of their marketing models. However, much remains to be done. I propose that now is the right time for pharmaceutical marketers (and scholars) to implement marketing strategies that help empowering patients. In addition, I also discuss the importance of avoiding that patient empowerment results in healthcare consumerism, which could have destructive consequences for patient–physician (and firm–physician) relationships.

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Notes

  1. 1.

    See Food and Drug Administration’s NDA 20-702, December 17, 1996, available at: http://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/020702_s000.pdf (last accessed September 19, 2011).

  2. 2.

    See, e.g., http://blogs.webmd.com/cosmetic-surgery/, the professional blog of Robert Kotler, M.D., a cosmetic surgeon in Beverly Hills.

  3. 3.

    In 2003, for example, Johns Hopkins and American Healthways (a Nashville-based company that provides specialized care and disease management services) dedicated their yearly Outcomes Summit to defining the patient–physician relationship. To promote dialogue about their evolving roles, they invited 200 patients and physicians to discuss the ideal patient–physician relationship for the twenty-first century. See http://www.cardiophonics.com/PatientPhysician.pdf, last accessed on March 3rd, 2012.

  4. 4.

    Another effect KOLs may have in market access is their capacity to influence the negotiation with regulators. Clinical KOLs, for instance, are by definition influential in scientific community, and many actually belong to the committees of regulatory bodies, even though such connections are increasingly scrutinized by other scientists and health authorities (Smith 2005). As evidence accumulates regarding the relationship of the industry with KOLs, their influence on other doctors may start to decline and regulation may decrease their influence on regulatory bodies (Smith 2005).

  5. 5.

    See story here: http://manly-daily.whereilive.com.au/news/story/survivors-win-fight-for-cheaper-cancer-drug/, accessed on March 2nd, 2012.

  6. 6.

    See http://pharmamkting.blogspot.com/, in particular, the post http://pharmamkting.blogspot.com/2010/03/sanofi-aventis-feels-social-media-pain.html, last accessed on March 2nd, 2012.

  7. 7.

    See http://www.doseofdigital.com/healthcare-pharma-social-media-wiki/.

  8. 8.

    See http://engagementstrategy.com/articles/announcing-the-winners-of-the-healthcare-engagement-strategy-awards-2012-hesawards/.

  9. 9.

    See  http://engagementstrategy.com/articles/astrazeneca-healthcare-engagement-strategy-2012-open-dialogue-award/.

  10. 10.

    See  http://engagementstrategy.com/articles/astrazeneca-healthcare-engagement-strategy-2012-open-dialogue-award/.

  11. 11.

    The academic literature on DTCA is extensive, and my goal here is to complement this literature with an overview of the effects of patient empowerment on DTCA, especially given the regulatory limitations of such communication. I refer the reader to excellent papers providing in-depth summaries of the literature on DTCA, such as Iizuka and Jin (2005), Kolsarici and Vakratsas (2010), Narayanan et al. (2004) and Osinga et al. (2011).

  12. 12.

    Available at http://www.ema.europa.eu.

  13. 13.

    In a rare study on this topic, Myers et al. (2011) show that in the erectile dysfunction category, individual traits are capable of predicting a patient’s likelihood to use prescription drugs without seeing a physician.

  14. 14.

    http://www.fosrenolontrack.com/patient/Default.aspx.

  15. 15.

    http://www.mysymbicort.com/.

  16. 16.

    http://www.simpill.com/.

  17. 17.

    I would like to thank Viorel Milea, at the Econometric Institute of the Erasmus School of Economics, for his invaluable help in the programming of the Python code I used to perform this content analysis.

References

  • Amaldoss W, He C (2009) Direct-to-consumer advertising of prescription drugs: a strategic analysis. Mark Sci 28(3):472–487

    Article  Google Scholar 

  • Bates A (2008) Patient compliance programs: how to ensure they are not doomed to fail. DTC Perspectives, March, pp 38–40

    Google Scholar 

  • Bodenheimer T, Lorig K, Holman H, Grumbach K (2002) Patient self-management of chronic disease in primary care. J Am Med Assoc 288(19):2469–2475

    Article  Google Scholar 

  • Bowman D, Heilman CM, Seetharaman PB (2004) Determinants of product-use compliance behavior. J Mark Res 41(August):324–338

    Article  Google Scholar 

  • Bridges JFP, Jones C (2007) Patient-based health technology assessment: a vision of the future. Int J Technol Assess Health Care 23(1):30–35

    Article  Google Scholar 

  • Cacciotti J, Clinton P (2011) 12th Annual pharm exec 50—the lull between two storms. Pharmaceutical Executive 31(5). http://www.oliverwyman.com/media/2011_PharmExec_50.pdf. Accessed 11 Oct 2011

  • Camacho N, Landsman V, Stremersch S (2010) The connected patient. In: Wuyts S, Dekimpe MG, Gijsbrechts E, Pieters R (eds) The connected customer: the changing nature of consumer and business markets. New-York, Routledge Academic, pp 107–140

    Google Scholar 

  • Camacho N, Donkers B, Stremersch S (2011) Predictably non-Bayesian: salience effects in physician learning about drug quality. Mark Sci 30(2):305–320

    Article  Google Scholar 

  • Chapman RH, Ferrufino CP, Kowal SL, Classi P, Roberts CS (2010) The cost and effectiveness of adherence-improving interventions for antihypertensive and lipid-lowering drugs. Int J Clin Pract 64(2):169–181

    Article  Google Scholar 

  • Charles C, Gafni A, Whelan T (1999) Decision-making in the physician–patient encounter: revisiting the shared treatment decision-making model. Soc Sci Med 49(5):651–661

    Article  Google Scholar 

  • Charles C, Gafni A, Whelan T, O’Brien MA (2006) Cultural influences on the physician-patient encounter: the case of shared treatment decision-making. Patient Educ Couns 63:262–267

    Article  Google Scholar 

  • Cherry B (2011a) Survivors win fight for cheaper cancer drug. Manly Daily, 31 August. http://manly-daily.whereilive.com.au/news/story/survivors-win-fight-for-cheaper-cancer-drug/. Accessed 2 March 2012

  • Cherry B (2011b) Blessed relief for Kristian. Manly Daily, 21 June. http://manly-daily.whereilive.com.au/news/story/blessed-relief-for-kristian/. Accessed 2 Mar 2012

  • Davies M (2008) Listening to consumers in a highly regulated environment: how pharmaceutical manufacturers can leverage consumer-generated media. Nielsen Online, August 2008. http://blog.nielsen.com/nielsenwire/wp-content/uploads/2009/11/Nielsen-Online-Healthcare-Practice_Social-Media-Adverse-Event-Reporting_nov09.pdf. Accessed 10 Oct 2011

  • Dellande S, Gilly MC, Graham JL (2004) Gaining compliance and losing weight: the role of the service provider in health care services. J Mark 68(July):78–91

    Article  Google Scholar 

  • Ding M, Eliashberg J (2008) A dynamic competitive forecasting model incorporating dyadic decision making. Manag Sci 54(4):820–834

    Article  Google Scholar 

  • Donohue JM, Cevasco M, Rosenthal MB (2007) A decade of direct-to-consumer advertising of prescription drugs. N Engl J Med 357(7):673–681

    Article  Google Scholar 

  • National Council on Patient Information and Education (2007) Enhancing prescription medicine adherence: a national action plan. NCPIE, Bethesda, MD. http://www.intelecare.com/downloads/ncpie-adherence-report.pdf. Accessed 16 Feb 2011

  • Epstein RM (2002) The patient-physician relationship (chapter 19). In: Mengel MB, Holleman WL, Fields SA (eds) Fundamentals of clinical practice, 2nd edn. Kluwer Academic/Plenum Publishers, New York, pp 403–429

    Chapter  Google Scholar 

  • Epstein RM, Alper BS, Quill TE (2004) Communicating evidence for participatory decision-making. J Am Med Assoc 291(19):2359–2366

    Article  Google Scholar 

  • Faden RR, Beauchamp TL (1986) A history and theory of informed consent. Oxford University Press, New York, NY

    Google Scholar 

  • Ferguson T, Frydman G (2004) The first generation of e-patients: these new medical colleagues could provide sustainable healthcare solutions. Br Med J 328(7449):1148–1149

    Article  Google Scholar 

  • Flocke SA, Miller WL, Crabtree BF (2002) Relationships between physician practice style, patient satisfaction, and attributes of primary care. J Fam Pract 51(10):835–840

    Google Scholar 

  • Fox S (2009) The social life of health information. Pew Internet & American Life Project, 11 June 2009. http://www.pewinternet.org/Reports/2009/8-The-Social-Life-of-Health-Information.aspx. Accessed 10 Oct 2011

  • Fox S (2011) Health topics. Pew Internet & American Life Project, 1 February 2011. http://www.pewinternet.org/Reports/2011/HealthTopics.aspx. Accessed 10 Oct

  • Garattini S, Chalmers I (2009) Patients and the public deserve big changes in evaluation of drugs. Br Med J 338(April):804–807

    Google Scholar 

  • Garnier J-P (2008) Rebuilding the R&D engine in big pharma. Harvard Business Review, May, pp 68–76

    Google Scholar 

  • Gilbert J, Henske P, Singh A (2003) Rebuilding big pharma’s business model. In Vivo 21(10):1–10

    Google Scholar 

  • Gilbody S, Wilson P, Watt I (2005) Benefits and harms of direct to consumer advertising: a systematic review. Qual Saf Health Care 14:246–250

    Article  Google Scholar 

  • Government Accountability Office (2006) Prescription drugs: improvements needed in FDA’s oversight of direct-to-consumer advertising. G.A.O., Washington, DC. http://prescriptiondrugs.procon.org/sourcefiles/Improvements_Needed_FDA’s_Oversight_DTC.pdf. Accessed 10 Feb 2011

  • Greene JA, Choudry NK, Kilabuk E, Shrank WH (2010) Online social networking by patients with diabetes: a qualitative evaluation of communication with facebook. J Gen Intern Med 26(3):287–292

    Article  Google Scholar 

  • Grundy SM, Cleeman JI, Merz CNB, Brewer HB Jr, Clark LT, Hunninghake DB, Pasternak RC, Smith SC Jr, Stone NJ (2004) Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines. Circulation 44(3):720–732

    Google Scholar 

  • Herxheimer A (2003) Relationships between the pharmaceutical industry and patients’ organisations. Br Med J 326(31):1208–1210

    Article  Google Scholar 

  • Hilsenrath P (2011) Health expenditure efficiency: implications for pharmaceutical marketing. Int J Pharm Healthc Mark 5(2):118–134

    Article  Google Scholar 

  • Hollon MF (1999) Direct-to-consumer marketing of prescription drugs creating consumer demand. J Am Med Assoc 281(4):382–384

    Article  Google Scholar 

  • Holmer AF (1999) Direct-to-consumer prescription drug advertising builds bridges between patients and physicians. J Am Med Assoc 281(4):380–382

    Article  Google Scholar 

  • Inglehart R, Baker WE (2000) Modernization, cultural change and the persistence of traditional values. Am Sociol Rev 65(1):19–51

    Article  Google Scholar 

  • Iizuka T, Jin GZ (2005) The effect of prescription drug advertising on doctor visits. J Econ Manag Strat 14(3):701–727

    Article  Google Scholar 

  • ‘t Jong GW, Stricker BHC, Sturkenboom MCJM (2004) Marketing in the lay media and prescriptions of terbinafine in primary care: Dutch cohort study. Br Med J 328:321

    Article  Google Scholar 

  • Kahn B, Luce MF (2003) Understanding high-stakes consumer decisions: mammography adherence following false-alarm test results. Mark Sci 22(3):393–410

    Article  Google Scholar 

  • Karlsson N, Loewenstein G, McCafferty J (2004) The economics of meaning. Nord J Polit Econ 30(1):61–75

    Google Scholar 

  • Kim HS, Sherman DK (2007) “Express yourself”: culture and the effect of self-expression on choice. J Pers Soc Psychol 92(1):1–11

    Article  Google Scholar 

  • Kolsarici C, Vakratsas D (2010) Category versus brand-level advertising messages in a highly regulated environment. J Mark Res 47(6):1078–1089

    Article  Google Scholar 

  • Krahn M, Naglie G (2008) The next step in guideline development: incorporating patient preferences. J Am Med Assoc 300(4):436–438

    Article  Google Scholar 

  • Kremer STM, Bijmolt THA, Leeflang PSH, Wieringa JE (2008) Generalizations on pharmaceutical marketing effectiveness. Int J Res Mark 25(4):234–246

    Article  Google Scholar 

  • Kumar V, Aksoy L, Donkers B, Venkatesan R, Wiesel T, Tillmanns S (2010) Undervalued or overvalued customers: capturing total customer engagement value. J Serv Res 13(3):297–310

    Article  Google Scholar 

  • Lee KL, Fader P, Hardie B (2007) How to project patient persistency. Foresight 8(Fall):31–35

    Google Scholar 

  • Luce MF, Kahn BE (1999) Avoidance or vigilance? The psychology of false-positive test results. J Consum Res 26(3):242–259

    Article  Google Scholar 

  • Manchanda P, Wittink DR, Ching A, Cleanthous P, Ding M, Dong XJ, Leeflang PS, Misra S, Mizik N, Narayanan S, Steenburgh T, Wieringa JE, Wosinska M, Xie Y (2005) Understanding firm, physician and consumer choice behavior in the pharmaceutical industry. Mark Lett 16(3/4):293–308

    Article  Google Scholar 

  • McNutt RA (2004) Shared medical decision making: problems, process, progress. J Am Med Assoc 292(20):2516–2518

    Article  Google Scholar 

  • Morgan M (1991) The doctor-patient relationship. In: Scrambler G (ed) Sociology as applied to medicine. Bailliere-Tindall, London, pp 49–65

    Google Scholar 

  • Morgan RM, Hunt SD (1994) The commitment–trust theory of relationship marketing. J Mark 58(July):20–38

    Article  Google Scholar 

  • Moynihan R, Heath I, Henry D (2002) Selling sickness: the pharmaceutical industry and disease mongering. Br Med J 324(7342):886–891

    Article  Google Scholar 

  • Murray CJL, Lopez AD (1996) Evidence-based health policy—lessons from the global burden of disease study. Science 274(5288):740–743

    Article  Google Scholar 

  • Myers SD, Royne MB, Deitz GD (2011) Direct-to-consumer advertising: exposure, behavior, and policy implications. J Public Policy Mark 30(1):110–118

    Article  Google Scholar 

  • Nair HS, Manchanda P, Bhatia T (2010) Asymmetric social interactions in physician prescription behavior: the role of opinion leaders. J Mark Res 47(October):883–895

    Article  Google Scholar 

  • Narayanan S, Desiraju R, Chintagunta PK (2004) Return on investment implications for pharmaceutical promotional expenditures: the role of marketing-mix interactions. J Market 68(4): 90–105

    Article  Google Scholar 

  • Narayanan S, Manchanda P, Chintagunta PK (2005) Temporal differences in the role of marketing communication in a new product category. J Mark Res 42(3):278–290

    Article  Google Scholar 

  • National Voices (2010) Annual report and accounts. http://www.nationalvoices.org.uk/sites/www.nationalvoices.org.uk/files/final_national_voices-statutory_accounts_2010_signed_0.pdf. Accessed 17 Jun 2013

  • National Center on Addiction and Substance Abuse (2005) Under the counter: the diversion and abuse of controlled prescription drugs in the U.S. Columbia University, New York, NY

    Google Scholar 

  • Neslin SA, Rhoads EE, Wolfson P (2009) A model and empirical analysis of patient compliance and persistence in pharmaceuticals. Working paper, Dartmouth College, Hanover, NH

    Google Scholar 

  • CBS News (2007) AIDS group sues Pfizer over Viagra ads. http://www.cbsnews.com/stories/2007/01/22/health/main2385992.shtml. Accessed 10 Feb 2011

  • Noble CH, Sinha RK, Kumar A (2002) Market orientation and alternative strategic orientations: a longitudinal assessment of performance implications. J Mark 66(4):25–39

    Article  Google Scholar 

  • Osinga EC, Leeflang PSH, Srinivasan S, Wieringa JE (2011) Why do firms invest in consumer advertising with limited sales response? A shareholder perspective. J Mark 75(January):109–124

    Article  Google Scholar 

  • Palmatier RW, Dant RP, Grewal D, Evans KR (2006) Factors influencing the effectiveness of relationship marketing: a meta-analysis. J Mark 70(October):136–153

    Article  Google Scholar 

  • Parsons T (1951) The social system. Free Press, Glencoe, IL

    Google Scholar 

  • Pauwels RA, Buist AS, Calverley PMA, Jenkins CR, Hurd SS (2001) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary. Am J Respir Crit Care Med 163(5):1256–1276

    Article  Google Scholar 

  • Prahalad CK, Ramaswamy V (2000) Co-opting customer competence. Harv Bus Rev 78(January–February):79–87

    Google Scholar 

  • Ringler J (2011) CBI conference highlights innovative programs on patient compliance. http://blog.pharmexec.com/2011/05/25/cbi-conference-highlights-innovative-programs-on-patient-compliance/. Accessed 16 Oct 2011

  • Roter D, Hall JA (2006) Doctors talking with patients/patients talking with doctors: improving communication in medical visits, 2nd edn. Praeger Publishers, Westport, CT

    Google Scholar 

  • Saroglou V, Delpierre V, Dernelle R (2004) Values and religiosity: a meta-analysis of studies using Schwartz’s model. Pers Individ Dif 37:721–734

    Article  Google Scholar 

  • Sheridan SL, Harris RP, Woolf SH (2004) Shared decision-making about screening and chemoprevention—a suggested approach from the U.S. preventive services task force. Am J Prev Med 26(1):56–66

    Article  Google Scholar 

  • Smith R (2005) Curbing the influence of the drug industry: a British view. PLoS Med 2(9):e241

    Article  Google Scholar 

  • Starr P (1982) The social transformation of American medicine. Basic Books, New York

    Google Scholar 

  • Stremersch S, Van Dyck W (2009) Marketing of the life sciences: a new framework and research agenda for a nascent field. J Mark 73(July):4–30

    Article  Google Scholar 

  • Terry NP (2010) Physicians and patients who “friend” or “tweet”: constructing a legal framework for social networking in a highly regulated domain. Indiana Law Rev 43(2):285–341

    Google Scholar 

  • The Economist (2007) Beyond the blockbuster: drugs firms are rethinking their business model. http://www.economist.com/node/9409230. Accessed 17 Oct 2011

  • Vargo SL, Lusch RF (2004) Evolving to a new dominant logic for marketing. J Mark 68(January):1–17

    Google Scholar 

  • Venkataraman S, Stremersch S (2007) The debate on influencing doctors’ decisions: are drug characteristics the missing link? Manag Sci 53(11):1688–1701

    Article  Google Scholar 

  • Verhoef PC, Reinartz WJ, Krafft M (2010) Customer engagement as a new perspective in customer management. J Serv Res 13(3):247–252

    Article  Google Scholar 

  • Verniers I, Stremersch S, Croux C (2011) The global entry of new pharmaceuticals: a joint investigation of launch window and price. International J Res Mark 28(4):(forthcoming)

    Google Scholar 

  • Weintraub A (2007) The doctor won’t see you now. BusinessWeek, 5 February

    Google Scholar 

  • Wilkes MS, Bell RA, Kravitz RL (2000) Direct-to-consumer prescription drug advertising: trends, impact, and implications. Health Aff 19(2):110

    Article  Google Scholar 

  • Wosinska M (2005) Direct-to-consumer advertising and drug therapy compliance. J Mark Res 42(August):323–332

    Article  Google Scholar 

  • Wright C (2010) The doctor won’t see you (Mr. Pharma Rep), now. PR Newswire, May 6. http://www.prnewswire.com/news-releases/the-doctor-wont-see-you-mr-pharma-rep-now-92964699.html. Accessed 17 Jun 2013

  • Young HN, Bell RA, Epstein RM, Feldman MD, Kravitz RL (2008) Physicians’ shared decision-making behaviors in depression care. Arch Intern Med 168(13):1404–1408

    Article  Google Scholar 

  • Zerhouni E (2003) The NIH roadmap. Science 302(5642):63–72

    Article  Google Scholar 

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Correspondence to Nuno Camacho .

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Appendix: Dictionary of Terms Used to Identify Patient Orientation

Appendix: Dictionary of Terms Used to Identify Patient Orientation

Patient empowerment

Informed patient

Patient support

Patient community

Patient communities

Social media

Shared decision-making

Disease awareness campaign

Mobile marketing

Packaging

Labeling

Holistic healthcare

Patient adherence

Therapy adherence

Patient compliance

Therapy compliance

Patient nonadherence

Patient non-adherence

Therapy nonadherence

Therapy non-adherence

Patient noncompliance

Therapy noncompliance

Direct-to-patient

Direct-to-consumer

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Camacho, N. (2014). Patient Empowerment: Consequences for Pharmaceutical Marketing and for the Patient–Physician Relationship. In: Ding, M., Eliashberg, J., Stremersch, S. (eds) Innovation and Marketing in the Pharmaceutical Industry. International Series in Quantitative Marketing, vol 20. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7801-0_14

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