Abstract
Big Pharma’s blockbuster model—which entails developing new drugs for diseases affecting a very large number of patients, promoting it to physicians as the new best-in-class treatment, and profiting from the ensuing volume of sales—is under threat. In the last 2 decades, the largest pharmaceutical firms have lost billions of dollars in shareholder value, due to a combination of factors such as declining R&D productivity, stricter regulatory requirements, more intense generic competition, and an increasingly ineffective marketing model. I review societal, demographic, regulatory, and technological trends and discuss how such trends are contributing to the rise of a new class of empowered patients. I discuss the implications of patient empowerment for the patient–physician relationship and for therapy launch and therapy promotion. Building on real-world evidence, I discuss the benefits and challenges of direct-to-patient marketing strategies such as nurturing partnerships with key patient opinion leaders and direct-to-patient communication via social media. Through a content analysis of the 2005–2010 annual reports of the largest 20 pharmaceutical firms, I show that, despite strict regulatory requirements, several firms have started to embrace patient empowerment as a key component of their marketing models. However, much remains to be done. I propose that now is the right time for pharmaceutical marketers (and scholars) to implement marketing strategies that help empowering patients. In addition, I also discuss the importance of avoiding that patient empowerment results in healthcare consumerism, which could have destructive consequences for patient–physician (and firm–physician) relationships.
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Notes
- 1.
See Food and Drug Administration’s NDA 20-702, December 17, 1996, available at: http://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/020702_s000.pdf (last accessed September 19, 2011).
- 2.
See, e.g., http://blogs.webmd.com/cosmetic-surgery/, the professional blog of Robert Kotler, M.D., a cosmetic surgeon in Beverly Hills.
- 3.
In 2003, for example, Johns Hopkins and American Healthways (a Nashville-based company that provides specialized care and disease management services) dedicated their yearly Outcomes Summit to defining the patient–physician relationship. To promote dialogue about their evolving roles, they invited 200 patients and physicians to discuss the ideal patient–physician relationship for the twenty-first century. See http://www.cardiophonics.com/PatientPhysician.pdf, last accessed on March 3rd, 2012.
- 4.
Another effect KOLs may have in market access is their capacity to influence the negotiation with regulators. Clinical KOLs, for instance, are by definition influential in scientific community, and many actually belong to the committees of regulatory bodies, even though such connections are increasingly scrutinized by other scientists and health authorities (Smith 2005). As evidence accumulates regarding the relationship of the industry with KOLs, their influence on other doctors may start to decline and regulation may decrease their influence on regulatory bodies (Smith 2005).
- 5.
See story here: http://manly-daily.whereilive.com.au/news/story/survivors-win-fight-for-cheaper-cancer-drug/, accessed on March 2nd, 2012.
- 6.
See http://pharmamkting.blogspot.com/, in particular, the post http://pharmamkting.blogspot.com/2010/03/sanofi-aventis-feels-social-media-pain.html, last accessed on March 2nd, 2012.
- 7.
- 8.
- 9.
- 10.
- 11.
The academic literature on DTCA is extensive, and my goal here is to complement this literature with an overview of the effects of patient empowerment on DTCA, especially given the regulatory limitations of such communication. I refer the reader to excellent papers providing in-depth summaries of the literature on DTCA, such as Iizuka and Jin (2005), Kolsarici and Vakratsas (2010), Narayanan et al. (2004) and Osinga et al. (2011).
- 12.
Available at http://www.ema.europa.eu.
- 13.
In a rare study on this topic, Myers et al. (2011) show that in the erectile dysfunction category, individual traits are capable of predicting a patient’s likelihood to use prescription drugs without seeing a physician.
- 14.
- 15.
- 16.
- 17.
I would like to thank Viorel Milea, at the Econometric Institute of the Erasmus School of Economics, for his invaluable help in the programming of the Python code I used to perform this content analysis.
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Appendix: Dictionary of Terms Used to Identify Patient Orientation
Appendix: Dictionary of Terms Used to Identify Patient Orientation
Patient empowerment
Informed patient
Patient support
Patient community
Patient communities
Social media
Shared decision-making
Disease awareness campaign
Mobile marketing
Packaging
Labeling
Holistic healthcare
Patient adherence
Therapy adherence
Patient compliance
Therapy compliance
Patient nonadherence
Patient non-adherence
Therapy nonadherence
Therapy non-adherence
Patient noncompliance
Therapy noncompliance
Direct-to-patient
Direct-to-consumer
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Camacho, N. (2014). Patient Empowerment: Consequences for Pharmaceutical Marketing and for the Patient–Physician Relationship. In: Ding, M., Eliashberg, J., Stremersch, S. (eds) Innovation and Marketing in the Pharmaceutical Industry. International Series in Quantitative Marketing, vol 20. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7801-0_14
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