Cholesterol and Its Role in Synaptic Transmission
Certain level of membrane cholesterol, which is an abundant constituent of eukaryotic membranes, is very important for normal functioning of a number of membrane proteins involved in synaptic transmission, such as ion channels, pumps, receptors, and transporters, while the alterations in cholesterol content change the property of membranes and the activity of these proteins. Moreover, cholesterol deficiency has been implicated in the pathogenesis of several neurodegenerative disorders.
KeywordsCholesterol Permeability Oligosaccharide Kelly Cyclodextrin
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