MRI-Guided Interstitial Laser Therapy of Brain Tumors

  • Sudhakar Vadivelu
  • Michael Schulder


Recurrent brain tumors present a daunting task when recalcitrant to surgical resection, chemotherapy, and radiosurgery. Alternative therapies are desirable when standard neuro-oncologic means are exhausted. Since the 1960s, lasers have been used in medical care at varying levels for the purpose of biomodulation; this includes laser-induced tissue stimulation, coagulation, cutting, and ablation. Here, we discuss a thermography-guided laser ablation technique, representing a novel approach to resistant brain tumors. A growing body of knowledge is accumulating evidence regarding laser-induced thermal ablation techniques for visceral-based tumors. We share our experience employing this novel technique towards recurrent central nervous system tumors with intraoperative MR guidance and discuss current indications and future considerations towards this alternative therapy.


Laser Fiber Thermal Ablation Burr Hole Recurrent Central Nervous System Proton Resonance Frequency Shift 
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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of NeurosurgeryThe Cushing Neuroscience Institute, Hofstra North Shore – LIJ School of MedicineManhassetUSA

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