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Making a Confident Diagnosis of Obliterative Bronchiolitis

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Bronchiolitis Obliterans Syndrome in Lung Transplantation

Part of the book series: Respiratory Medicine ((RM,volume 8))

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Abstract

Bronchiolitis obliterans syndrome (BOS) is a dreaded complication of lung transplantation. Despite the fact that over 50 % of lung transplant recipients will eventually be diagnosed with BOS, it remains a challenging diagnosis to make with complete certainty. This diagnostic dilemma is a product of the inherent limitations of spirometry, the parameter upon which the diagnosis relies, as well as the many confounding diagnoses that must be considered and excluded before the diagnosis of BOS can be made. This chapter seeks to explore the diagnostic challenges surrounding BOS with the aim of establishing a diagnostic framework to assist the clinician with making a more confident diagnosis of BOS.

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Author information

Authors and Affiliations

  1. Advanced Lung Disease and Lung Transplant Program, Inova Fairfax Hospital, Falls Church, VA, USA

    A. Whitney Brown M.D. & Steven D. Nathan M.D.

Authors
  1. A. Whitney Brown M.D.
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  2. Steven D. Nathan M.D.
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Correspondence to Steven D. Nathan M.D. .

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Editors and Affiliations

  1. School of Medicine & Public Health, Dept. Internal Medicine, Sect. Allergy, University of Wisconsin, Highland Avenue 600, Madison, 53792-9988, Wisconsin, USA

    Keith C. Meyer

  2. Lung Transplant Unit, St. Vincent's Hospital, Victoria Street, Darlinghurst, Sydney, 2010, New South Wales, Australia

    Allan R. Glanville

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Brown, A.W., Nathan, S.D. (2013). Making a Confident Diagnosis of Obliterative Bronchiolitis. In: Meyer, K., Glanville, A. (eds) Bronchiolitis Obliterans Syndrome in Lung Transplantation. Respiratory Medicine, vol 8. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4614-7636-8_5

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  • DOI: https://doi.org/10.1007/978-1-4614-7636-8_5

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  • Publisher Name: Humana Press, New York, NY

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  • Online ISBN: 978-1-4614-7636-8

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