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Microelectrode Voltage Clamp: The Cardiac Purkinje Fiber

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Book cover Voltage and Patch Clamping with Microelectrodes

Abstract

Cardiac muscle, like skeletal muscle and nerves, is electrically excitable. Local stimulation by a brief electrical shock of adequate strength generates an impulse that propagates in a regenerative manner to distal regions. Although the diversity of electrical activity in the heart contrasts with the homogeneity of nerve and skeletal muscle action potentials, cardiac electrical impulses are generated by membrane permeability changes that generally resemble those in other excitable cells.

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Author information

Authors and Affiliations

  1. Department of Physiology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

    Robert S. Kass & Paul B. Bennett

Authors
  1. Robert S. Kass
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  2. Paul B. Bennett
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Editor information

Editors and Affiliations

  1. Laboratory of Neurophysiology, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Maryland, USA

    Thomas G. Smith Jr.

  2. Laboratory of Biophysics, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Maryland, USA

    Harold Lecar

  3. Experimental Neurology Unit, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia

    Steven J. Redman

  4. Department of Physiology, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia

    Peter W. Gage

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© 1985 American Physiological Society

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Kass, R.S., Bennett, P.B. (1985). Microelectrode Voltage Clamp: The Cardiac Purkinje Fiber. In: Smith, T.G., Lecar, H., Redman, S.J., Gage, P.W. (eds) Voltage and Patch Clamping with Microelectrodes. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7601-6_8

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  • DOI: https://doi.org/10.1007/978-1-4614-7601-6_8

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7601-6

  • eBook Packages: Springer Book Archive

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