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Prevalence and Associated Conditions

  • Shelley R. Hart
  • Stephen E. Brock
  • Ida Jeltova
Chapter
Part of the Developmental Psychopathology at School book series (DPS)

Abstract

As indicated in previous chapters, a complete understanding of bipolar disorder remains elusive, particularly with an early-onset of the disorder. As such, an accurate accounting of how common this disorder is in the general population also remains to be unequivocally made. However, a recent meta-analysis of epidemiologic, community-based studies has estimated the prevalence of an early-onset bipolar disorder to be approximately 1.8% (Van Meter, Moreira, & Youngstrom, 2011). As subthreshold cases are included, estimates increase to 6–7% (see Van Meter, Moreira, et al., 2011 for studies included in this meta-analysis). These subthreshold cases are particularly important as research has demonstrated that a substantial majority—almost half—of these individuals will convert to a bipolar I or bipolar II diagnosis in their youth (Axelson et al., 2011).

Keywords

Attention Deficit Hyperactivity Disorder Bipolar Disorder Anxiety Disorder Conduct Disorder Oppositional Defiant Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Achenbach, T. M. (1991). Manual for the Child Behavior Checklist/4-18 and 1991 profile. Burlington, VT: University of Vermont Department of Psychiatry.Google Scholar
  2. Alloy, L. B., Abramson, L. Y., Urosevic, S., Walshaw, P. D., Nusslock, R., & Neeren, A. M. (2005). The psychosocial context of bipolar disorder: Environmental, cognitive, and developmental risk factors. Clinical Psychology Review, 25, 1043–1075. doi: 10.1016/j.cpr.2005.06.006.PubMedGoogle Scholar
  3. Althoff, R. R., Ayer, L. A., Rettew, D. C., & Hudziak, J. J. (2010). Assessment of dysregulated children using the Child Behavior Checklist: A receiver operating characteristic curve analysis. Psychological Assessment, 22, 609–617. doi: 10.1037/a0019699.PubMedGoogle Scholar
  4. Althoff, R. R., Faraone, S. V., Rettew, D. C., Morley, C. P., & Hudziak, J. J. (2005). Family, twin, adoption, and molecular genetic studies of juvenile bipolar disorder. Bipolar Disorders, 7, 598–609. doi: 10.1111/j.1399-5618.2005.00268.x.PubMedGoogle Scholar
  5. Alvarez, M.-J., Roura, P., Oses, A., Foguet, Q., Sola, J., & Arrufat, F.-X. (2011). Prevalence and clinical impact of childhood trauma in patients with severe mental disorders. The Journal of Nervous and Mental Disease, 199, 156–161. doi: 10.1097/NMD.0b013e31820c751c.PubMedGoogle Scholar
  6. American Psychiatric Association. (2002). Practice guideline for the treatment of patients with bipolar disorder (2nd ed.). Retrieved from http://www.psych.org/psych_pract/treatg/pg/Bipolar2ePG_05-15-06.pdf
  7. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.Google Scholar
  8. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders: Fourth edition-text revision (DSM-IV-TR). Washington, DC: Author.Google Scholar
  9. Andersen, M., Kubisak, J. B., Field, R., & Vogelstein, S. (2003). Understanding and educating children and adolescents with bipolar disorder: A guide for educators. Northfield, IL: Josselyn Center.Google Scholar
  10. Anglada, T. (2006). Intense minds: Through the eyes of young people with bipolar disorder. Victoria, BC: Trafford Publishing.Google Scholar
  11. Angst, J., Azorin, J.-M., Bowden, C. L., Perugi, G., Vieta, E., Gamma, A., et al. (2011). Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: The BRIDGE study. Archives of General Psychiatry, 68, 791–798. doi: 10.1001/archgenpsychiatry.2011.87.PubMedGoogle Scholar
  12. Angst, J., Gamma, A., Benazzi, F., Ajdacic, V., Eich, D., & Rössler, W. (2003). Toward a re-definition of subthreshold bipolarity: Epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania. Journal of Affective Disorders, 73, 133–146. doi: 10.1016/S0165-0327(02)00322-1.PubMedGoogle Scholar
  13. Angst, J., Gamma, A., Benazzi, F., Silverstein, B., Ajdacic-Gross, V., Eich, D., et al. (2006). Atypical depressive syndromes in varying definitions. European Archives of Psychiatry and Clinical Neuroscience, 256, 44–54. doi: 10.1007/s00406-005-0600-z.PubMedGoogle Scholar
  14. Angst, J., Sellaro, R., Stassen, H. H., & Gamma, A. (2005). Diagnostic conversion from depression to bipolar disorders: Results of a long-term prospective study of hospital admissions. Journal of Affective Disorders, 84, 149–157. doi: 1016/S0165-0327(03)00195-2.PubMedGoogle Scholar
  15. Angst, J., Stassen, H. H., Clayton, P. J., & Angst, J. (2002). Mortality of patients with mood disorders: Follow-up over 34–38 years. Journal of Affective Disorders, 68, 167–181. doi: 10.1016/S0165-0327(01)00377-9.PubMedGoogle Scholar
  16. Arnold, L. E., Demeter, C., Mount, K., Frazier, T. W., Youngstrom, E. A., Fristad, M., et al. (2011). Pediatric bipolar spectrum disorder and ADHD: Comparison and comorbidity in the LAMS clinical sample. Bipolar Disorders, 13, 509–521. doi: 10.1111/j.1399-5618.2011.00948.x.PubMedGoogle Scholar
  17. Assion, H.-J., Brune, N., Schmidt, N., Aubel, T., Edel, M.-A., Basilowski, M., et al. (2009). Trauma exposure and post-traumatic stress disorder in bipolar disorder. Social Psychiatry and Psychiatric Epidemiology, 44, 1041–1049. doi: 10.1007/s00127-009-0029-1.PubMedGoogle Scholar
  18. Axelson, D. A., Birmaher, B., Strober, M. A., Goldstein, B. I., Ha, W., Gill, M. K., et al. (2011). Course of subthreshold bipolar disorder in youth: Diagnostic progression from bipolar disorders not otherwise specified. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 1001–1016. doi: 10.1016/j.jaac.2011.07.005.PubMedGoogle Scholar
  19. Axelson, D. A., Birmaher, B., Strober, M., Gill, M. K., Valeri, S., Chiapetta, L., et al. (2006). Phenomenology of children and adolescents with bipolar spectrum disorders. Archives of General Psychiatry, 63, 1139–1148. doi: 10.1001/archpsych.63.10.1139.PubMedGoogle Scholar
  20. Balázs, J., Benazzi, F., Rihmer, Z., Rihmer, A., Akiskal, K. K., & Akiskal, H. S. (2006). The close link between suicide attempts and mixed (bipolar) depression: Implications for suicide prevention. Journal of Affective Disorders, 91, 133–138. doi: 10.1016/j.jad.2005.12.049.PubMedGoogle Scholar
  21. Bauer, M. S., Kirk, G. F., Gavin, C., & Williford, W. O. (2001). Determinants of functional outcome and healthcare costs in bipolar disorder: A high-intensity follow-up study. Journal of Affective Disorders, 65, 231–245. doi: 10.1016/S0165-0327(00)00247-0.PubMedGoogle Scholar
  22. Bearden, C. E., Glahn, D. C., Caetano, S., Olvera, R. L., Fonseca, M., Najt, P., et al. (2007). Evidence for distruption in prefrontal cortical functions in juvenile bipolar disorder. Bipolar Disorders, 9, 145–159. doi: 10.1111/j.1399-5618.2007.00453.x.PubMedGoogle Scholar
  23. Bella, T., Goldstein, T., Axelson, D., Obreja, M., Monk, K., Hickey, M. B., et al. (2011). Psychosocial functioning in offspring of parents with bipolar disorder. Journal of Affective Disorders, 133, 204–211. doi: 10.1016/j.jad.2011.03.022.PubMedGoogle Scholar
  24. Benazzi, F. (2007). Challenging DSM-IV criteria for hypomania: Diagnosing based on number of no-priority symptoms. European Psychiatry, 22, 99–103. doi: 10.1016/j.eurpsy.2006.06.003.PubMedGoogle Scholar
  25. Benes, F. M., & Berretta, S. (2001). GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology, 25, 1–27. doi: 10.1016/S0893-133X(01)00225-1.PubMedGoogle Scholar
  26. Bentall, R. P., Myin-Germeys, I., Smith, A., Knowles, R., Jones, S. H., Smith, T., et al. (2011). Hypomanic personality, stability of self-esteem and response styles to negative mood. Clinical Psychology & Psychotherapy, 18, 397–410. doi: 10.1002/cpp.780.Google Scholar
  27. Bhangoo, R. K., Dell, M. L., Towbin, K. E., Myers, F. S., Lowe, C. H., Pine, D. S., et al. (2003). Clinical correlates of episodicity in juvenile mania. Journal of Child and Adolescent Psychopharmacology, 13, 507–514. doi: 10.1089/104454603322724896.PubMedGoogle Scholar
  28. Biederman, J., Faraone, S., Chu, M. P., & Wozniak, J. (1999). Further evidence of a bidirectional overlap between juvenile mania and conduct disorder in children. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 468–476. doi: 10.1097/00004583-199904000-00021.PubMedGoogle Scholar
  29. Biederman, J., Faraone, S., Mick, E., Wozniak, J., Chen, L., Ouellette, C., et al. (1996). Attention-deficit hyperactivity disorder and juvenile mania: An overlooked comorbidity? Journal of the American Academy of Child and Adolescent Psychiatry, 35, 997–1008. doi: 10.1097/00004583-199608000-00010.PubMedGoogle Scholar
  30. Biederman, J., Faraone, S., Wozniak, J., Mick, E., Kwon, A., Cayton, G. A., et al. (2005). Clinical correlates of bipolar disorder in a large, referred sample of children and adolescents. Journal of Psychiatric Research, 39, 611–622. doi: 10.1016/j.jpsychires.2004.08.003.PubMedGoogle Scholar
  31. Biederman, J., Kwon, A., Wozniak, J., Mick, E., Markowitz, S., Fazio, V., et al. (2004). Absence of gender differences in pediatric bipolar disorder: Findings from a large sample of referred youth. Journal of Affective Disorders, 83, 207–214. doi: 10.1016/j.jad.2004.08.005.PubMedGoogle Scholar
  32. Biederman, J., Petty, C. R., Byrne, D., Wong, P., Wozniak, J., & Faraone, S. V. (2009). Risk for switch from unipolar to bipolar disorder in youth with ADHD: A long term prospective controlled study. Journal of Affective Disorders, 119, 16–21. doi: 10.1016/j.jad.2009.02.024.PubMedGoogle Scholar
  33. Birmaher, B., Arbelaez, C., & Brent, D. (2002). Course and outcome of child and adolescent major depressive disorder. Child and Adolescent Psychiatric Clinics of North America, 11, 619–638. doi: 10.1016/S1056-4993(02)00011-1.PubMedGoogle Scholar
  34. Birmaher, B., Axelson, D., Goldstein, B., Strober, M., Gill, M. K., Hunt, J., et al. (2009). Four-year longitudinal course of children and adolescents with bipolar spectrum disorders: The course and outcome of bipolar youth (COBY) study. The American Journal of Psychiatry, 166, 795–804. doi: 10.1176/appi.ajp.2009.08101569.PubMedGoogle Scholar
  35. Birmaher, B., Axelson, D., Strober, M., Gill, M. K., Valeri, S., Chiapetta, L., et al. (2006). Clinical course of children and adolescents with bipolar spectrum disorders. Archives of General Psychiatry, 63, 175–183. doi: 10.1001/archpsyc.63.2.175.PubMedGoogle Scholar
  36. Birmaher, B., Axelson, D., Strober, M., Gill, M. K., Yang, M., Ryan, N., et al. (2009). Comparison of manic and depressive symptoms between children and adolescents with bipolar spectrum disorders. Bipolar Disorders, 11, 52–62. doi: 10.1111/j.1399-5618.2008.00659.x.PubMedGoogle Scholar
  37. Blader, J. C. (2011). Acute inpatient care for psychiatric disorders in the United States, 1996 through 2007. Archives of General Psychiatry, 68, 1276–1283. doi: 10.1001/archgenpsychiatry.2011.84.PubMedGoogle Scholar
  38. Blader, J. C., & Carlson, G. A. (2007). Increased rate of bipolar diagnoses among U. S. child, adolescent, and adult inpatients, 1996–2004. Biological Psychiatry, 62, 107–114. doi: 10.1016/j.biopsych.2006.11.006.PubMedGoogle Scholar
  39. Boomsma, D. I., Rebollo, I., Derks, E. M., van Beijsterveldt, T. C. E. M., Althoff, R. R., Rettew, D. C., et al. (2006). Longitudinal stability of the CBCL-juvenile bipolar disorder phenotype: A study of Dutch twins. Biological Psychiatry, 60, 912–920. doi: 10.1016/j.biopsych.2006.02.028.PubMedGoogle Scholar
  40. Braaten, E. (2007). The child clinician’s report-writing handbook. New York, NY: Guilford Press.Google Scholar
  41. Brieger, P., Röttig, S., Röttig, D., Marneros, A., & Priebe, S. (2007). Dimensions underlying outcome criteria in bipolar I disorder. Journal of Affective Disorders, 99, 1–7. doi: 10.1016/j.jad.2006.08.012.PubMedGoogle Scholar
  42. Bressert, S. (2007, February 23). The causes of bipolar disorder (manic depression ). Retrieved April 11, 2009, from http://psychcentral.com/lib/2007/the-causes-of-bipolar-disorder-manic-depression/
  43. Brock, S. E., Jimerson, S. R., & Hansen, R. (2009). Identifying, assessing, and treating ADHD at school. New York: Springer.Google Scholar
  44. Brock, S. E., Jimerson, S. R., & Hansen, R. L. (2006). Identifying, assessing, and treating autism at school. New York: Springer.Google Scholar
  45. Brock, S. E., Sandoval, J., & Hart, S. (2006). Suicidal ideation and behaviors. In G. Bear & K. Minke (Eds.), Children’s needs III: Understanding and addressing the developmental needs of children. Bethesda, MD: National Association of School Psychologists.Google Scholar
  46. Carlat, D. J. (1998). The psychiatric review of symptoms: A screening tool for family physicians. American Family Physician, 58, 1617–1624. Retrieved from http://www.aafp.org/.PubMedGoogle Scholar
  47. Carlson, G. A., & Glovinsky, I. (2009). The concept of bipolar disorder in children: A history of the bipolar controversy. Child and Adolescent Psychiatric Clinics of North America, 18, 257–271. doi: 10.1016/j.chc.2008.11.003.PubMedGoogle Scholar
  48. Carlson, G., & Kelly, K. (1998). Manic symptoms in psychiatrically hospitalized children—What do they mean? Journal of Affective Disorders, 51, 123–135. doi: 10.1016/S0165-0327(98)00211-0.PubMedGoogle Scholar
  49. Carter, A. S., & Briggs-Gowan, M. J. (2000). Manual of the Infant-Toddler Social-Emotional Assessment. New Haven, CT: Yale University Press.PubMedGoogle Scholar
  50. Carter, A. S., Briggs-Gowan, M. J., & Davis, N. O. (2004). Assessment of young children’s social-emotional development and psychopathology: Recent advances and recommendations for practice. Journal of Child Psychology and Psychiatry, 45, 109–134. doi: 10.1046/j.0021-9630.2003.00316.x.PubMedGoogle Scholar
  51. Carter, T. D. C., Mundo, E., Parikh, S. V., & Kennedy, J. L. (2003). Early age at onset as a risk factor for poor outcome of bipolar disorder. Journal of Psychiatric Research, 37, 297–303. doi: 10.1016/S0022-3956(03)00052-9.PubMedGoogle Scholar
  52. Chan, J., Stringaris, A., & Ford, T. (2010). Bipolar disorder in children and adolescents recognised in the UK: A clinic-based study. Child and Adolescent Mental Health, 16, 71–78. doi: 10.1111/j.1475-3588.2010.00566.x.Google Scholar
  53. Chang, K. D. (2008). The use of atypical antipsychotics in pediatric bipolar disorder. Journal of Clinical Psychiatry, 69(Suppl. 4), 4–8. www.psychiatrist.com.PubMedGoogle Scholar
  54. Chang, K., Adleman, N., Wagner, C., Barnea-Goraly, N., & Garrett, A. (2006). Will neuroimaging ever be used to diagnose pediatric bipolar disorder? Development and Psychopathology, 18, 1133–1146. doi: 10.1017/S09545794060548.PubMedGoogle Scholar
  55. Chang, K. D., Steiner, H., & Ketter, T. A. (2000). Psychiatric phenomenology of child and adolescent bipolar offspring. Journal of the American Academy of Child and Adolescent Psychiatry, 39(4), 453–460. doi: 10.1097/00004583-200004000-00014.PubMedGoogle Scholar
  56. Chou, J. C.-Y. (2004). Review and update of the American Psychiatric Association practice guideline for bipolar disorder. Primary Psychiatry, 11(9), 73–84. www.primarypsychiatry.com.Google Scholar
  57. Coletti, D. J., Leigh, E., Galleli, K. A., & Kafantaris, V. (2005). Patterns of adherence to treatment in adolescents with bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 15, 913–917. doi: 10.1089/cap.2005.15.913.PubMedGoogle Scholar
  58. Colom, F., Vieta, E., Martinez-Arán, A., Reinares, M., Goikolea, J. M., Benabarre, A., et al. (2003). A randomized trial on the efficacy of group psychoeducation in the prophylaxis of recurrences in bipolar patients whose disease is in remission. Archives of General Psychiatry, 60, 402–407. doi: 10.1001/archpsyc.60.4.402.PubMedGoogle Scholar
  59. Consoli, A., Deniau, E., Huynh, C., Purper, D., & Cohen, D. (2007). Treatments in child and adolescent bipolar disorder. European Child & Adolescent Psychiatry, 16, 187–198. doi: 10.1007/s00787-006-0587-7.Google Scholar
  60. Conus, P., Cotton, S., Schimmelmann, B. G., Berk, M., Daglas, R., McGorry, P. D., et al. (2010). Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania. Bipolar Disorders, 12, 244–252. doi: 10.1111/j.1399-5618.2010.00813.x.PubMedGoogle Scholar
  61. Correll, C. U. (2008). Weight gain and metabolic abnormalities in pediatric bipolar disorder. In B. Geller & M. P. DelBello (Eds.), Treatment of bipolar disorder in children and adolescents (pp. 361–391). New York, NY: Guilford Press.Google Scholar
  62. Coryell, W., Solomon, D., Turvey, C., Keller, M., Leon, A. C., Endicott, J., et al. (2003). The long-term course of rapid-cycling bipolar disorder. Archives of General Psychiatry, 60, 914–920. doi: 10.1001/archpsyc.60.9.914.PubMedGoogle Scholar
  63. Cotter, D., Landau, S., Beasley, C., Stevenson, R., Chana, G., & MacMillan, L. (2002). The density and spatial distribution of GABAergic neurons, labeled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia. Biological Psychiatry, 51, 377–386. doi: 10.1016/S0006-3223(01)01243-4.PubMedGoogle Scholar
  64. Craddock, N., O’Donovan, M. C., Owen, M. J. (2005). The genetics of schizophrenia and bipolar disorder: Dissecting psychosis. Journal of Medical Genetics, 42, 193–204. doi: 10.1136/jmg.2005.030718.Google Scholar
  65. Crick, N. R., & Dodge, K. A. (1994). A review and reformulation of social information-processing mechanisms in children’s social adjustment. Psychological Bulletin, 115, 74–101. doi: 10.1037/0033-2909.115.1.74.Google Scholar
  66. Culver, J. L., Arnow, B. A., & Ketter, T. A. (2007). Bipolar disorder: Improving diagnosis and optimizing integrated care. Journal of Clinical Psychology, 63, 73–92. doi: 10.1002/jclp.20333.PubMedGoogle Scholar
  67. Danielyan, A., Pathak, S., Kowatch, R. A., Arszman, S. P., & Johns, E. S. (2007). Clinical characteristics of bipolar disorder in very young children. Journal of Affective Disorders, 97, 51–59. doi: 10.1016/j.jad.2006.05.028.PubMedGoogle Scholar
  68. Davis, R. E. (1979). Manic-depressive variant syndrome of childhood: A preliminary report. American Journal of Psychiatry, 136, 702–706. http://ajp.psychiatryonline.org/journal.aspx?journalid=13.PubMedGoogle Scholar
  69. DelBello, M. P., Schwiers, M. L., Rosenberg, H. L., & Strakowski, S. M. (2002). A double-blind, placebo-controlled study of quetiapine as adjunctive treatment for adolescent mania. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 1216–1223. doi: 10.1097/00004583-200210000-00011.PubMedGoogle Scholar
  70. DelBello, M., Soutullo, C., Hendricks, W., Niemeier, R., McElroy, S., & Strakowski, S. (2001). Prior stimulant treatment in adolescents with bipolar disorder: Association with age at onset. Bipolar Disorders, 3, 53–57. doi: 10.1034/j.1399-5618.2001.030201.x.PubMedGoogle Scholar
  71. Deveney, C. M., Brotman, M. A., Decker, A. M., Pine, D. S., & Leibenluft, E. (2012). Affective prosody labeling in youths with bipolar disorder or severe mood dysregulation. Journal of Child Psychology and Psychiatry, 53, 262–270. doi: 10.1111/j.1469-7610.2011.02482.x.PubMedGoogle Scholar
  72. Diflorio, A., & Jones, I. (2010). Is sex important? Gender differences in bipolar disorder. International Review of Psychiatry, 22, 437–452. doi: 10.3109/09540261.2010.514601.PubMedGoogle Scholar
  73. Diler, R. S., Uguz, S., Seydaoglu, G., Erol, N., & Avci, A. (2007). Differentiating bipolar disorder in Turkish prepubertal children with attention-deficit hyperactivity disorder. Bipolar Disorders, 9, 243–251. doi: 10.1111/j.1399-5618.2007.00347.x.PubMedGoogle Scholar
  74. Doran, C. M. (2008). The hypomania handbook: The challenge of elevated mood. Philadelphia, PA: Lippincott Williams & Wilkins.Google Scholar
  75. Drotar, D., Greenley, R. N., Demeter, C. A., McNamara, N. K., Stansbrey, R. J., Calabrese, J. R., et al. (2007). Adherence to pharmacological treatment for juvenile bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 831–839. doi: 10.1097/chi.0b013e31805c7421.PubMedGoogle Scholar
  76. DSM-5 Childhood and Adolescent Disorders Work Group (2010). Justification for Temper Dysregulation Disorder with Dysphoria. Retrieved from www.dsm5.org
  77. DSM-5 Mood Disorders and Childhood and Adolescent Disorders Work Groups (2010). Issues pertinent to a developmental approach to bipolar disorder in DSM-5. Retrieved from www.dsm5.org
  78. DSM-5 Mood Disorders Work Group (2012). Proposal to eliminate bereavement exclusion criteria from major depressive episode in DSM-5. Retrieved from www.dsm5.org
  79. Duax, J. M., Youngstrom, E. A., Calabrese, J. R., & Findling, R. L. (2007). Sex differences in pediatric bipolar disorder. The Journal of Clinical Psychiatry, 68, 1565–1573. doi: 10.4088/JCP.v68n1016.PubMedGoogle Scholar
  80. Duffy, A., Alda, M., Hajek, T., Sherry, S. B., & Grof, P. (2010). Early stages in the development of bipolar disorder. Journal of Affective Disorders, 121, 127–135. doi: 10.1016/j.jad.2009.05.022.PubMedGoogle Scholar
  81. Duffy, F. F., Narrow, W. E., Rae, D. S., West, J. C., Zarin, D. A., Rubio-Stipec, M., et al. (2005). Concomitant pharmacotherapy among youths treated in routine psychiatric practice. Journal of Child and Adolescent Psychopharmacology, 15, 12–25. doi: 10.1089/cap.2005.15.12.PubMedGoogle Scholar
  82. Eckblad, M., & Chapman, L. J. (1986). Development and validation of a scale for hypomanic personality. Journal of Abnormal Psychology, 95, 214–222. doi: 10.1037/0021-843X.95.3.214.PubMedGoogle Scholar
  83. Emilien, G., Septien, L., Brisard, C., Corruble, E., & Bourin, M. (2007). Bipolar disorder: How far are we from a rigorous definition and effective management? Progress in Neuro-Psychopharmacology & Biological Psychiatry, 31, 975–996. doi: 10.1016/j.pnpbp.2007.03.005.Google Scholar
  84. Esposito-Smythers, C., Birmaher, B., Valeri, S., Chiapetti, L., Hunt, J., Ryan, N., et al. (2006). Child co-morbidity, maternal mood disorder, and perceptions of family functioning among bipolar youth. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 955–964. doi: 10.1097/01.chi.0000222785.11359.04.PubMedGoogle Scholar
  85. Evans-Lacko, S. E., Zeber, J. E., Gonzalez, J. M., & Olvera, R. L. (2009). Medical comorbidity among youth diagnosed with bipolar disorder in the United States. The Journal of Clinical Psychiatry, 70, 1461–1466. doi: 10.4088/JCP.08m04871.PubMedGoogle Scholar
  86. Eyberg, S. M., & Ross, A. W. (1978). Assessment of child behavior problems: The validation of a new inventory. Journal of Clinical Child Psychology, 7, 113–116. doi: 10.1080/15374417809532835.PubMedGoogle Scholar
  87. Faedda, G. L., Baldessarini, R. J., Glovinsky, I. P., & Austin, N. B. (2004). Pediatric bipolar disorder: Phenomenology and course of illness. Bipolar Disorders, 6, 305–313. doi: 10.1111/j.1399-5618.2004.00128.x.PubMedGoogle Scholar
  88. Faraone, S. V., Althoff, R. R., Hudziak, J. J., Monuteaux, M., & Biederman, J. (2005). The CBCL predicts DSM bipolar disorder in children: A receiver operating characteristic curve analysis. Bipolar Disorders, 7, 518–524. doi: 10.1111/j.1399-5618.2005.00271.x.PubMedGoogle Scholar
  89. Faraone, S. V., Glatt, S. J., Su, J., & Tsuang, M. T. (2004). Three potential susceptibility loci shown by a genome-wide scan for regions influencing the age at onset of mania. The American Journal of Psychiatry, 161, 625–630. doi: 10.1176/appi.ajp.161.4.625.PubMedGoogle Scholar
  90. Fatemi, S. H., Stary, J. M., Earle, J. A., Araghi-Niknam, M., & Eagan, E. (2005). GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. Schizophrenia Research, 72, 109–122. doi: 10.1016/j.schres.2004.02.017.PubMedGoogle Scholar
  91. Faust, E. S., Walker, D., & Sands, M. (2006). Diagnosis and management of childhood bipolar disorder in the primary care setting. Clinical Pediatrics, 45, 801–808. doi: 10.1177/0009922806295279.PubMedGoogle Scholar
  92. Findling, R. L., Frazier, J. A., Kafantaris, V., Kowatch, R., McClellan, J., Pavuluri, M., et al. (2008). The collaborative lithium trials (CoLT): Specific aims, methods, and implementation. Child and Adolescent Psychiatry and Mental Health, 2, 21–34. doi: 10.1186/1753-2000-2-21.PubMedGoogle Scholar
  93. Findling, R. L., & Pavuluri, M. N. (2008). Lithium. In B. Geller & M. P. DelBello (Eds.), Treatment of bipolar disorder in children and adolescents (pp. 43–68). New York: Guilford.Google Scholar
  94. Food and Drug Administration (2007a). FDA proposes new warnings about suicidal thinking, behavior in young adults who take antidepressant medications. FDA News. Retrieved from http://www.fda.gov/bbs/topics/NEWS/2007/NEW01624.html
  95. Food and Drug Administration (2007b). Revisions to product labeling. Retrieved from http://www.fda.gov/cder/drug/antidepressants/antidepressants_label_change_2007.pdf
  96. Frank, E. (2005). Treating bipolar disorder: A clinician’s guide to interpersonal and social rhythm therapy. New York, NY: Guilford Press.Google Scholar
  97. Frank, E., Kupfer, D. J., Thase, M. E., Mallinger, A. G., Swartz, H. A., Faiolini, A. M., et al. (2005). Two-year outcomes for interpersonal and social rhythm therapy in individuals with bipolar I disorder. Archives of General Psychiatry, 62, 996–1004. doi: 10.1001/archpsyc.62.9.996.PubMedGoogle Scholar
  98. Freeman, A. J., Youngstrom, E. A., Frazier, T. W., Youngstrom, J. K., Demeter, C., & Findling, R. L. (2011). Portability of a screener for pediatric bipolar disorder to a diverse setting. Psychological Assessment, 24, 341–351. doi: 10.1037/s0025617.PubMedGoogle Scholar
  99. Freeman, A. J., Youngstrom, E. A., Michalak, E., Siegel, R., Meyers, O. I., & Findling, R. L. (2009). Quality of life in pediatric bipolar disorder. Pediatrics, 123, e446–e452. doi: 10.1542/peds.2008-0841.PubMedGoogle Scholar
  100. Frazier, J. A., Bregman, H. R., & Jackson, J. A. (2008). Atypical antipsychotics in the treatment of early-onset bipolar disorder. In B. Geller & M. P. DelBello (Eds.), Treatment of bipolar disorder in children and adolescents (pp. 69–108). New York, NY: Guilford Press.Google Scholar
  101. Fristad, M. A., Davidson, K. H., & Leffler, J. M. (2007). Thinking-feeling-doing: A therapeutic technique for children with bipolar disorder and their parents. Journal of Family Psychotherapy, 18, 81–103. doi: 10.1300/J085v18n04_06.Google Scholar
  102. Fristad, M. A., Verducci, J. S., Walters, K., & Young, M. E. (2009). Impact of multifamily psychoeducational psychotherapy in treating children aged 8 to 12 years with mood disorders. Archives of General Psychiatry, 66, 1013–1020. doi: 10.1001/archgenpsychiatry.2009.112.PubMedGoogle Scholar
  103. Galanter, C. A., & Leibenluft, E. (2008). Frontiers between attention deficit hyperactivity and bipolar disorder. Child and Adolescent Psychiatric Clinics of North America, 17, 325–346. doi: 10.1016/j.chc.2007.11.001.PubMedGoogle Scholar
  104. Geller, B., Bolhofner, K., Craney, J. L., Williams, M., DelBello, M. P., & Gundersen, K. (2000). Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype. Journal of the American Academy of Child and Adolescent Psychiatry, 39(12), 1543–1548. doi: 10.1097/00004583-200012000-00018.PubMedGoogle Scholar
  105. Geller, B., Craney, J. L., Bolhofner, K., Nickelsburg, M. J., Williams, M., & Zimerman, B. (2002). Two-year prospective follow-up children with a prepubertal and early adolescent bipolar disorder phenotype. The American Journal of Psychiatry, 159, 927–933. doi: 10.1176/appi.ajp.159.6.927.PubMedGoogle Scholar
  106. Geller, B., Tillman, R., & Bolhofner, K. (2007). Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults. Journal of Child and Adolescent Psychopharmacology, 17, 217–222. doi: 10.1089/cap.2007.0017.PubMedGoogle Scholar
  107. Geller, B., Williams, M., Zimerman, B., Frazier, J., Beringer, L., & Warner, K. L. (1998). Prepubertal and early adolescent bipolarity differentiate from ADHD by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling. Journal of Affective Disorders, 51, 81–91. doi: 10.1016/S0165-0327(98)00175-X.PubMedGoogle Scholar
  108. Geller, B., Zimerman, B., Williams, M., Bolhofner, K., Craney, J. L., DelBello, M., et al. (2001). Reliability of the Washington University in St Louis Kiddi Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) mania and rapid cycling sections. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 450–455. doi: 10.1097/00004583-200104000-00014.PubMedGoogle Scholar
  109. Ghaemi, S. N., Ko, J. Y., & Goodwin, F. K. (2001). The bipolar spectrum and the antidepressant view of the world. Journal of Psychiatric Practice, 287–297. doi: 10.1097/00131746-200109000-00002
  110. Ghaziuddin, N., Kutcher, S. P., Knapp, P., Bernet, W., Arnold, V., Beitchman, J., et al. (2004). Practice parameter for use of electroconvulsive therapy with adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1521–15399. doi: 10.1097/01.chi.0000142280.87429.68.PubMedGoogle Scholar
  111. Gibbons, R. D., Brown, C. H., Hur, K., Marcus, S. M., Bhaumik, D. K., Erkens, J. A., et al. (2007). Early evidence on the effects of regulators’ suicidality warnings on SSRI prescriptions and suicide in children and adolescents. The American Journal of Psychiatry, 164, 1356–1363. doi: 10.1176/appi.ajp.2007.07030454.PubMedGoogle Scholar
  112. Gilcher, D., Field, R., & Hellander, M. (2004). The IDEA classification debate: ED or OHI? CABF e Bulletin. Retrieved from http://www.bpkids.org/site/DocServer/field_idea_classification.pdf?docID=169
  113. Glahn, D. C., Bearden, C. E., Bowden, C. L., & Soares, J. C. (2006). Reduced educational attainment in bipolar disorder. Journal of Affective Disorders, 92, 309–312.PubMedGoogle Scholar
  114. Goetz, I., Tohen, M., Reed, C., Lorenzo, M., & Vieta, E. (2007). Functional impairment in patients with mania: Baseline results of the EMBLEM study. Bipolar Disorders, 9, 45–52. doi: 10.1111/j.1399-5618.2007.00325.x.PubMedGoogle Scholar
  115. Gogtay, N., Ordonez, A., Herman, D. H., Hayashi, K. M., Greenstein, D., Vaituzis, C., et al. (2007). Dynamic mapping of cortical development before and after the onset of pediatric bipolar illness. Journal of Child Psychology and Psychiatry, 48, 852–862. doi: 10.1111/j.1469-7610.2007.01747.x.PubMedGoogle Scholar
  116. Goldberg, J. F., & Ernst, C. L. (2004). Clinical correlates of childhood and adolescent adjustment in adult patients with bipolar disorder. The Journal of Nervous and Mental Disease, 192, 187–192. doi: 10.1097/01.nmd.0000116461.53411.ab.PubMedGoogle Scholar
  117. Goldberg, J. F., Perlis, R. H., Ghaemi, S. N., Calabrese, J. R., Bowden, C. L., Wisniewski, S., et al. (2007). Adjunctive antipressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: Findings from the STEP-BD. The American Journal of Psychiatry, 164, 1348–1355. doi: 10.1176/appi.ajp.2007.05122032.PubMedGoogle Scholar
  118. Goldstein, B. I. (2012). Recent progress in understanding pediatric bipolar disorder. Archives of Pediatrics & Adolescent Medicine, 166, 362–371. doi: 10.1001/archpediatrics.2011.832.Google Scholar
  119. Goldstein, B. I., & Bukstein, O. G. (2010). Comorbid substance use disorders among youth with bipolar disorder: Opportunities for early identification and prevention. The Journal of Clinical Psychiatry, 71, 348–358. doi: 10.4088/JCP.09r05222gry.PubMedGoogle Scholar
  120. Goldstein, B. I., Strober, M. A., Birmaher, B., Axelson, D. A., Esposito-Smythers, C., Goldstein, T. R., et al. (2008). Substance use disorders among adolescents with bipolar spectrum disorders. Bipolar Disorders, 10, 469–478. doi: 10.1111/j.1399-5618.2008.00584.x.PubMedGoogle Scholar
  121. Goldstein, T. R. (2009). Suicidality in pediatric bipolar disorder. Child and Adolescent Psychiatric Clinics of North America, 18, 339–352. doi: 10.1016/j.chc.2008.11.005.PubMedGoogle Scholar
  122. Goldstein, T. R., Axelson, D. A., Birmaher, B., & Brent, D. A. (2007). Dialectical behavior therapy for adolescents with bipolar disorder: A 1-year open trial. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 820–830. 10.1097.chi.0b013e31805c1613.PubMedGoogle Scholar
  123. Goldstein, T. R., Birmaher, B., Axelson, D., Goldstein, B. I., Gill, M. K., Esposito-Smythers, C., et al. (2009). Psychosocial functioning among bipolar youth. Journal of Affective Disorders, 114, 174–183. doi: 10.1016/j.jad.2008.07.001.PubMedGoogle Scholar
  124. Goldstein, T. R., Birmaher, B., Axelson, D., Ryan, N. D., Strober, M. A., Gill, M. K., et al. (2005). History of suicide attempts in pediatric bipolar disorder: Factors associated with increased risk. Bipolar Disorders, 7, 525–535. 1111/j.1399-5618.2005.00263.x.PubMedGoogle Scholar
  125. Goldstein, T. R., Miklowitz, D. J., & Mullen, K. L. (2006). Social skills knowledge and performance among adolescents with bipolar disorders. Bipolar Disorders, 8, 350–361. doi: 10.1111/j.1399-5618.2006.00321.x.PubMedGoogle Scholar
  126. Gottesman, I. I., Laursen, T. M., Bertelsen, A., & Mortensen, P. B. (2010). Severe mental disorders in offspring with 2 psychiatrically ill parents. Archives of General Psychiatry, 67, 252–257. doi: 10.1001/archgenpsychiatry.2010.1.PubMedGoogle Scholar
  127. Gracious, B. L., Chirieac, M. C., Costescu, S., Finucane, T. L., Youngstrom, E. A., & Hibbeln, J. R. (2010). Randomized, placebo-controlled trial of flax oil in pediatric bipolar disorder. Bipolar Disorders, 12, 142–154. doi: 10.1111/j.1399-5618.2010.00799.x.PubMedGoogle Scholar
  128. Greene, R. W., & Doyle, A. E. (1999). Toward a transactional conceptualization of oppositional defiant disorder: Implications for assessment and treatment. Clinical Child and Family Psychology Review, 2, 129–148. doi: 10.1023/A:1021850921476.PubMedGoogle Scholar
  129. Greenwood, T. A., Alexander, M., Keck, P. E., McElroy, S., Sadovnick, A. D., Remick, R. A., & Kelsoe, J. R. (2001). Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder. American Journal of Medical Genetics, 105, 145–151. doi: 10.1002/1096-8628.Google Scholar
  130. Gresham, F. (2007). Response to intervention and emotional and behavioral disorders: Best practices in assessment for intervention. Assessment for Effective Intervention, 32, 214–222. doi: 10.1177/15345084070320040301.Google Scholar
  131. Grisso, T. (2008). Adolescent offenders with mental disorders. The Future of Children, 18, 143–162. 10.1353.foc.0.0016.PubMedGoogle Scholar
  132. Guyer, A. E., McClure, E. B., Adler, A. D., Brotman, M. A., Rich, B. A., Kimes, A. S., et al. (2007). Specificity of facial expression labeling deficits in childhood psychopathology. Journal of Child Psychology and Psychiatry, 48, 863–871. doi: 10.1111/j.1469-7610.2007.01758.x.PubMedGoogle Scholar
  133. Hamrin, V., & Iennaco, J. D. (2010). Psychopharmacology of pediatric bipolar disorder. Expert Reviews of Neurotherapy, 10, 1053–1088. 10.1586.ERN.10.86.Google Scholar
  134. Harpaz-Rotem, I., Leslie, D. L., Martin, A., & Rosenheck, R. A. (2005). Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000. Social Psychiatry and Psychiatric Epidemiology, 40, 642–647. doi: 10.1007/s00127-005-0923-0.PubMedGoogle Scholar
  135. Harpaz-Rotem, I., & Rosenheck, R. A. (2004). Changes in outpatient psychiatric diagnosis in privately insured children and adolescents from 1995 to 2000. Child Psychiatry and Human Development, 34(4), 329–340. doi: 10.1023/B:CHUD.0000020683.08514.2d.PubMedGoogle Scholar
  136. Hauser, M., Pfennig, A., Özgürdal, S., Heinz, A., Bauer, M., & Juckel, G. (2007). Early recognition of bipolar disorder. European Psychiatry, 22, 92–98. doi: 10.1016/j.eurpsy.2006.08.003.PubMedGoogle Scholar
  137. Hayden, E. P., & Nurnberger, J. I. (2006). Molecular genetics of bipolar disorder. Genes, Brain, and Behavior, 5, 85–95. doi: 10.1111/j.1601-183X.2005.00138.x.PubMedGoogle Scholar
  138. Henin, A., Beiderman, J., Mick, E., Hirshfeld-Becker, D. R., Sachs, G. S., Wu, Y., et al. (2007). Childhood antecedent disorders to bipolar disorder in adults: A controlled study. Journal of Affective Disorders, 99, 51–57. doi: 10.1016/j.jad.2006.09.001.PubMedGoogle Scholar
  139. Henin, A., Mick, E., Biederman, J., Faraone, S. V., Fried, R., Wozniak, J., et al. (2007). Can bipolar disorder-specific neuropsychological impairments in children be identified? Journal of Consulting and Clinical Psychology, 75, 210–220. doi: 10.1037/0022-006X.75.2.210.PubMedGoogle Scholar
  140. Henry, D. B., Pavuluri, M. N., Youngstrom, E., Birmaher, B. (2008). Accuracy of brief and full forms of the Child Mania Rating Scale. Journal of Clinical Psychology, 64, 368–381. doi: 10.1002/jclp.20464.PubMedGoogle Scholar
  141. Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., Calabrese, J. R., Flynn, L., Keck, P. E., ... Zajecka, J. (2000). Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire. American Journal of Psychiatry, 157, 1873–1875. doi: 10.1176/appi.ajp.157.11.1873.PubMedGoogle Scholar
  142. Hirschfeld, R. M., Lewis, L., & Vornik, L. A. (2003). Perceptions and impact of bipolar disorder: How far have we really come? Results of the National Depressive and Manic-Depressive Association 2000 survey of individuals with bipolar disorder. The Journal of Clinical Psychiatry, 64, 161–174. doi: 10.4088/JCP.v64n0209.PubMedGoogle Scholar
  143. Hirschfeld, R. M. A., Holzer, C., Calabrese, J. R., Weissman, M., Reed, M., Davies, M., ... Hazard, E. (2003). Validity of the Mood Disorder Questionnaire: A general population study. American Journal of Psychiatry, 160, 178–180. doi: 10.1176/appi.ajp.160.1.178.PubMedGoogle Scholar
  144. Hlastala, S. A., Kotler, J. S., McClellan, J. M., & McCauley, E. A. (2010). Interpersonal and social rhythm therapy for adolescents with bipolar disorder: Treatment development and results from an open trial. Depression and Anxiety, 27, 457–464. doi: 10.1002/da.20668.PubMedGoogle Scholar
  145. Holtmann, M., Bölte, S., Goth, K., Döpfner, M., Plück, J., Huss, M., et al. (2007). Prevalence of the CBCL-pediatric bipolar disorder phenotype in a German general population sample. Bipolar Disorders, 9, 895–900. doi: 10.1111/j.1399-5618.2007.00463.x.PubMedGoogle Scholar
  146. Horn, K., Roessner, V., & Holtmann, M. (2011). Neurocognitive performance in children and adolescents with bipolar disorder: A review. European Child & Adolescent Psychiatry, 20, 433–450. doi: 10.1007/s00787-011-0209-x.Google Scholar
  147. Houston, J. E., Shevlin, M., Adamson, G., & Murphy, J. (2011). A person-centred approach to modelling population experiences of trauma and mental illness. Social Psychiatry and Psychiatric Epidemiology, 46, 149–157. doi: 10.1007/s00127-009-0176-4.PubMedGoogle Scholar
  148. Hua, L. L., Wilens, T. E., Martelon, M., Wong, P., Wozniak, J., & Biederman, J. (2010). Psychosocial functioning, familiarity, and psychiatric comorbidity in bipolar youth with and without psychotic features. The Journal of Clinical Psychiatry, 72, 397–405. doi: 10.4088/JCP.10m06025yel.Google Scholar
  149. Hughes, C. W., Emslie, G. J., Wohlfahrt, H., Winslow, R., Kashner, R. M., & Rush, A. J. (2005). Effect of structured interviews on evaluation time in pediatric community mental health settings. Psychiatric Services, 56, 1098–1103. doi: 10.1176/appi.ps.56.9.1098.PubMedGoogle Scholar
  150. Huxley, N., & Baldessarini, R. J. (2007). Disability and its treatment in bipolar disorder patients. Bipolar Disorders, 9, 183–196. doi: 10.1111/j.1399-5618.2007.00430.x.PubMedGoogle Scholar
  151. Individuals with Disabilities Education Improvement Act. (2004). Retrieved from www.ed.gov/about/offices/list/osers/osep/index.html
  152. Jaeger, J., Berns, S., Loftus, S., Gonzalez, C., & Czobor, P. (2007). Neurocognitive test performance predicts functional recovery from acute exacerbation leading to hospitalization in bipolar disorder. Bipolar Disorders, 9, 93–102. doi: 10.1111/j.1399-5618.2007.00427.x.PubMedGoogle Scholar
  153. Jairam, R., Srinath, S., Girimaji, S. C., & Seshadri, S. P. (2004). A prospective 4–5 year follow-up of juvenile onset bipolar disorder. Bipolar Disorders, 6, 386–394. doi: 10.1111/j.1399-5618.2004.00149.x.PubMedGoogle Scholar
  154. Jensen, P. S., Buitelaar, J., Pandina, G. J., Binder, C., & Haas, M. (2007). Management of psychiatric disorders in children and adolescents with atypical antipsychotics: A systematic review of published clinical trials. European Child & Adolescent Psychiatry, 16, 104–120. doi: 10.1007/s00787-006-0580-1.Google Scholar
  155. Jerrell, J. M., McIntyre, R. S., & Tripathi, A. (2010). A cohort study of the prevalence and impact of comorbid medical conditions in pediatric bipolar disorder. The Journal of Clinical Psychiatry, 71, 1518–1525. doi: 10.4088/JCP.09m05585ora.PubMedGoogle Scholar
  156. Jerrell, J. M., McIntyre, R. S., & Tripathi, A. (2011). Childhood treatment with psychotropic medication and development of comorbid medical conditions in adolescent-onset bipolar disorder. Human Psychopharmacology: Clinical and Experimental, 26, 451–459. doi: 10.1002/hup.1227.Google Scholar
  157. Jerrell, J. M., & Prewette, E. D. (2008). Outcomes for youths with early- and very-early-onset bipolar I disorder. The Journal of Behavioral Health Services and Research, 35, 52–59. doi: 10.1007/s11414-007-9081-3.PubMedGoogle Scholar
  158. Jerrell, J. M., & Shugart, M. A. (2004). Community-based care for youths with early and very-early onset bipolar I disorder. Bipolar Disorders, 6, 299–304. doi: 10.1111/j.1399-5618.2004.00129.x.PubMedGoogle Scholar
  159. Jolin, E. M., Weller, E. B., & Weller, R. A. (2008a). Anxiety symptoms and syndromes in bipolar children and adolescents. Current Psychiatry Reports, 10, 123–129. doi: 10.1007/s11920-008-0022-5.PubMedGoogle Scholar
  160. Jones, S. H., & Bentall, R. P. (2008). A review of potential cognitive and environmental risk markers in children of bipolar parents. Clinical Psychology Review, 28, 1083–1095. doi: 10.1016/j.cpr.2008.03.002.PubMedGoogle Scholar
  161. Joseph, M. F., Frazier, T. W., Youngstrom, E. A., & Soares, J. C. (2008). A quantitative and qualitative review of neurocognitive performance in pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 18, 595–605. doi: 10.1089/cap.2008.064.PubMedGoogle Scholar
  162. Joshi, G. G., & Wilens, T. (2009). Comorbidity in pediatric bipolar disorder. Child and Adolescent Psychiatric Clinics of North America, 18, 291–319. doi: 10.1016/j.chc.2008.12.005.PubMedGoogle Scholar
  163. Joshi, P. T., & Robb, A. S. (2008). Polycystic ovary syndrome. In B. Geller & M. P. DelBello (Eds.), Treatment of bipolar disorder in children and adolescents (pp. 333–360). New York, NY: Guilford Press.Google Scholar
  164. Judd, L. L., & Akiskal, H. S. (2003). The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases. Journal of Affective Disorders, 73, 123–131. doi: 10.1016/S0165-0327(02)00332-4.PubMedGoogle Scholar
  165. Judd, L. L., Akiskal, H. S., Schettler, P. J., Coryell, W., Maser, J., Rice, J. A., et al. (2003). The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: A clinical spectrum or distinct disorders? Journal of Affective Disorders, 73, 19–32. doi: 10.1016/S0165-0327(02)00324-5.PubMedGoogle Scholar
  166. Judd, L. L., Akiskal, H. S., Schettler, P. J., Endicott, J., Leon, A. C., Solomon, D. A., et al. (2005). Psychosocial disability in the course of bipolar I and II disorders. Archives of General Psychiatry, 62, 1322–1330. doi: 10.1001/archpsyc.62.12.1322.PubMedGoogle Scholar
  167. Kato, T. (2008). Molecular neurobiology of bipolar disorder: A disease of ‘mood-stabilizing nuerons’? Trends in Neurosciences, 31, 495–503. doi: 10.1016/j.tins.2008.07.007.PubMedGoogle Scholar
  168. Kamphaus, R. W., & Reynolds, C. R. (2007). The behavioral and emotional screening system. Autsin, TX: Pearson Assessment.Google Scholar
  169. Kamphaus, R. W., Thorpe, J., Winsor, A. P., Kroncke, A., Dowdy, E., & VanDeventer, M. (2007). Development and predictive validity of a teacher screener for child behavioral and emotional problems at school. Educational and Psychological Measurement, 67, 342–356. doi: 10.1177/00131644070670021001.PubMedGoogle Scholar
  170. Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for Affective Disorders and Schizophrenia for School-Age Children—Present and Lifetime Version (KSADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 980–988. doi: 10.1097/00004583-199707000-00021.PubMedGoogle Scholar
  171. Keenan-Miller, D., & Miklowitz, D. J. (2011). Interpersonal functioning in pediatric bipolar disorder. Clinical Psychology: Science and Practice, 18, 342–356. doi: 10.1111/j.1468-2850.2011.01266.x.Google Scholar
  172. Kempton, M. (2008). Bipolar disorder neuroimaging database (BiND). Retrieved June 4, 2008, from http://sites.google.com/site/bipolardatabase/
  173. Kempton, M., Geddes, J. R., Ettinger, U., Williams, S. C. R., & Grasby, P. M. (2008). Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder. Archives of General Psychiatry, 65, 1017–1032. doi: 10.1001/archpsyc.65.9.1017.PubMedGoogle Scholar
  174. Kerner, B., Lambert, C. G., & Muthén, B. O. (2011). Genome-wide association study in bipolar patients stratified by co-morbidity. PLoS One, 6, 1–10. doi: 10.1371/journal.pone.0028477.Google Scholar
  175. Kessler, R. C., Adler, L., Barkley, R., Biederman, J., Conners, C. K., Demler, O., et al. (2006). The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication. The American Journal of Psychiatry, 163, 716–723. doi: 10.1176/appi.ajp.163.4.716.PubMedGoogle Scholar
  176. Kilbourne, A. M., Cornelius, J. R., Han, X., Pincus, H. A., Shad, M., Salloum, I., et al. (2004). Burden of general medical conditions among individuals with bipolar disorder. Bipolar Disorders, 6, 368–373. doi: 10.1111/j.1399-5618.2004.00138.x.PubMedGoogle Scholar
  177. Kim, E. Y., & Miklowitz, D. J. (2002). Childhood mania, attention deficit hyperactivity disorder and conduct disorder: A critical review of diagnostic dilemmas. Bipolar Disorders, 4, 215–225. doi: 10.1034/j.1399-5618.2002.01191.x.PubMedGoogle Scholar
  178. Knowles, S., & Shear, N. H. (2009). Clinical risk management of Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum. Dermatologic Therapy, 22, 441–451. doi: 10.1111/j.1529-8019.2009.01260.x.PubMedGoogle Scholar
  179. Kovacs, M., Kovacs, M., & Pollack, M. (1995). Bipolar disorder and comorbid conduct disorder in childhood and adolescence. Journal of the American Academy of Children and Adolescent Psychiatry, 34, 526–529. www.jaacap.com.Google Scholar
  180. Kowatch, R. A. (2008). Mood stabilizers. In B. Geller & M. P. DelBello (Eds.), Treatment of bipolar disorder in children and adolescents (pp. 109–125). New York, NY: Guilford Press.Google Scholar
  181. Kowatch, R. A., Youngstrom, E. A., Danielyan, A., & Findling, R. L. (2005). Review and meta-analysis of the phenomenology and clinical characteristics of mania in children and adolescents. Bipolar Disorders, 7, 483–496. doi: 10.1111/j.1399-5618.2005.00261.x.PubMedGoogle Scholar
  182. Krishnan, K. R. R. (2005). Psychiatric and medical comorbidities of bipolar disorder. Psychosomatic Medicine, 67, 1–8. doi: 10.1097/01.psy.0000151489.36347.18.PubMedGoogle Scholar
  183. Kupka, R. W., Luckenbaugh, D. A., Post, R. M., Suppes, T., Altshuler, L. L., Keck, P. E., et al. (2005). Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. The American Journal of Psychiatry, 162, 1273–1280. doi: 10.1176/appi.ajp.162.7.1273.PubMedGoogle Scholar
  184. Kutcher, S., Robertson, H. A., & Bird, D. (1998). Premorbid functioning in adolescent onset bipolar I disorder: A preliminary report from an ongoing study. Journal of Affective Disorders, 51, 137–144. doi: 10.1016/S0165-0327(98)00212-2.PubMedGoogle Scholar
  185. Kwapil, T. R., Miller, M. B., Zinser, M. C., Chapman, L. J., Chapman, J., & Eckblad, M. (2000). A longitudinal study of high scorers on the hypomanic personality scale. Journal of Abnormal Psychology, 109, 222–226. doi: 10.1037/0021-843X.109.2.222.PubMedGoogle Scholar
  186. Labbe, C. (2007, September 1). Studies refine understanding of treatments for bipolar disorder. Retrieved from http://www.nimh.nih.gov/press/miklowitz_golbergstep.cfm
  187. Labbe, C. (2007, September 6). Global survey reveals significant gap in meeting worlds mental health care needs. Retrieved from http://www.nimh.nih.gov/press/wang_globalhealth.cfm
  188. Lacerda, L. T., Keshavan, M. S., Hardan, A. Y., Yorbik, O., Brambilla, P., Sassi, R. B., et al. (2004). Anatomic evaluation of the orbitofrontal cortex in major depressive disorder. Biological Psychiatry, 55, 353–358. doi: 10.1016/j.biopsych.2003.08.021.PubMedGoogle Scholar
  189. Lachman, H. M., Papolos, D. F., Saito, T., Yu, Y. M., Szumlanski, C. L., & Weinshilboum, R. M. (1996). Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6, 243–250. Retrieved from http://journals.lww.com/jpharmacogenetics/pages/default.aspx.Google Scholar
  190. Lagace, D. C., & Kutcher, S. P. (2005). Academic performance of adolescents with bipolar disorder. Directions in Psychiatry, 25, 111–117. doi.Google Scholar
  191. Lam, D. H., Watkins, E. R., Hayward, P., Bright, J., Wright, K., Kerr, N., et al. (2003). A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: Outcome of the first year. Archives of General Psychiatry, 60, 145–152. doi: 10.1001/archpsyc.60.2.145.PubMedGoogle Scholar
  192. Lasky, T., Krieger, A., Elixhauser, A., & Vitiello, B. (2011). Children’s hospitalizations with a mood disorder diagnosis in general hospitals in the United States 2000–2006. Child and Adolescent Psychiatry and Mental Health, 5, 27–35. doi: 10.1186/1753-2000-5-27.PubMedGoogle Scholar
  193. Leahy, R. L. (2007). Bipolar disorder: Causes, contexts, and treatments. Journal of Clinical Psychology: In Session, 83, 417–424. doi: 10.1002/jclp.20360.Google Scholar
  194. LeBuffe, P.A., & Naglieri, J.A. (2003). The Devereux Early Childhood Assessment Clinical Form (DECA-C): A measure of behaviors related to risk and resilience in preschool children. Lewisville, NC: Kaplan Press.Google Scholar
  195. Leibenluft, E. (2011). Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths. The American Journal of Psychiatry, 168, 129–142. doi: 10.1176/appi.ajp.2010.10050766.PubMedGoogle Scholar
  196. Leibenluft, E., Charney, D. S., Towbin, K. E., Bhangoo, R. K., & Pine, D. S. (2003). Defining clinical phenotypes of juvenile mania. The American Journal of Psychiatry, 160, 430–437. doi: 10.1176/appi.ajp.160.3.430.PubMedGoogle Scholar
  197. Leibenluft, E., Rich, B. A., Vinton, D. T., Nelson, E. E., Fromm, S. J., Berghorst, L. H., et al. (2007). Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder. The American Journal of Psychiatry, 164, 52–60. doi: 10.1176/appi.ajp.164.1.52.PubMedGoogle Scholar
  198. Levine, J., Chengappa, K. N. R., Brar, J. S., Gershon, S., & Kupfer, D. J. (2001). Illness characteristics and their association with prescription patterns for bipolar I disorder. Bipolar Disorders, 3, 41–49. doi: 10.1034/j.1399-5618.2001.030106.x.PubMedGoogle Scholar
  199. Lewinsohn, P. M., Klein, D. N., & Seeley, J. R. (1995). Bipolar disorders in a community sample of older adolescents: Prevalence, phenomenology, comorbidity and course. Journal of the American Academy of Child and Adolescent Psychiatry, 34, 454–463. doi: 10.1097/00004583-199504000-00012.PubMedGoogle Scholar
  200. Lewinsohn, P. M., Seeley, J. R., & Klein, D. N. (2003). Bipolar disorder in adolescents: Epidemiology and suicidal behavior. In B. Geller & M. P. DelBello (Eds.), Bipolar disorder in childhood and early adolescence (pp. 7–24). New York, NY: Guilford Press.Google Scholar
  201. Lofthouse, N., Fristad, M., Splaingard, M., & Kelleher, K. (2007). Parent and child reports of sleep problems associated with early-onset bipolar spectrum disorders. Journal of Family Psychology, 21, 114–123. doi: 10.1037/0893-3200.21.1.114.PubMedGoogle Scholar
  202. Lorberg, B., Wilens, T. E., Martelon, M., Wong, P., & Parcell, T. (2010). Reasons for substance use among adolescents with bipolar disorder. The American Journal on Addictions, 19, 474–480. doi: 10.1111/j.1521-0391.2010.00077.x.PubMedGoogle Scholar
  203. Luby, J., & Belden, A. (2006). Defining and validating bipolar disorder in the preschool period. Development and Psychopathology, 18, 971–988. doi: 10.1017/S0954579406060482.PubMedGoogle Scholar
  204. Luckenbaugh, D. A., Findling, R. L., Leverich, G. S., Pizzarello, S. M., & Post, R. M. (2009). Earliest symptoms discriminating juvenile-onset bipolar illness from ADHD. Bipolar Disorders, 11, 441–451. doi: 10.1111/j.1399-5618.2009.00684.x.PubMedGoogle Scholar
  205. Maayan, L., & Correll, C. U. (2011). Weight gain and metabolic risks associated with antipsychotic medications in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 21, 517–535. doi: 10.1089/cap.2011.0015.PubMedGoogle Scholar
  206. Manning, J. S. (2005). Burden of illness in bipolar depression. The Primary Care Companion to The Journal of Clinical Psychiatry, 7(6), 259–267. doi: 10.4088/PCC.v07n0601.Google Scholar
  207. Martínez-Arán, A., Vieta, E., Reinares, M., Colom, F., Torrent, C., Sánchez-Moreno, J., et al. (2004). Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. The American Journal of Psychiatry, 161, 262–270. doi: 10.1176/appi.ajp.161.2.262.PubMedGoogle Scholar
  208. Masi, G., Perugi, G., Toni, C., Millepiedi, S., Mucci, M., Bertini, N., et al. (2006). Attention-deficit hyperactivity disorder—bipolar comorbidity in children and adolescents. Bipolar Disorders, 8, 373–381. doi: 10.1111/j.1399-5618.2006.00342.x.PubMedGoogle Scholar
  209. Masi, G., Perugi, G., Millepiedi, S., Mucci, M., Toni, C., Bertini, N., et al. (2006). Developmental differences according to age at onset in juvenile bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 16, 679–685. doi: 10.1089/cap.2006.16.679.PubMedGoogle Scholar
  210. McClellan, J., Kowatch, R., Findling, R. L., Bernet, W., Bukstein, O., Beithchman, J., et al. (2007). Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 107–125. doi: 10.1016/j.jaac.2011.09.019.PubMedGoogle Scholar
  211. McClure-Tone, E. B. (2010). Social cognition and cognitive flexibility in BD. In D. J. Miklowitz & D. Cicchetti (Eds.), Understanding bipolar disorder: A developmental psychopathology perspective (pp. 331–369). New York, NY: Guilford Press.Google Scholar
  212. McClure, E. B., Treland, J. E., Snow, J., Schmajuk, M., Dickstein, D. P., Towbin, K. E., et al. (2005). Deficits in social cognition and response flexibility in pediatric bipolar disorder. The American Journal of Psychiatry, 162, 1644–1651. doi: 10.1176/appi.ajp.162.9.1644.PubMedGoogle Scholar
  213. McCombs, J. S., Ahn, J., Tencer, T., & Shi, L. (2007). The impact of unrecognized bipolar disorders among patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) program: A 6-year retrospective analysis. Journal of Affective Disorders, 97, 171–179. doi: 10.1016/j.jad.2006.06.018.PubMedGoogle Scholar
  214. McConaughy, S. H., & Ritter, D. R. (2008). Best practices in multimethod assessment of emotional and behavioral disorders. In A. Thomas & J. Grimes (Eds.), Best practices in school psychology V (Vol. 2, pp. 697–715). Bethesda, MD: National Association of School Psychologists.Google Scholar
  215. McElroy, S. L., Kotwal, R., & Keck, P. E. (2006). Comorbidity of eating disorders with bipolar disorder and treatment implications. Bipolar Disorders, 8, 686–695. doi: 10.1111/j.1399-5618.2006.00401.x.PubMedGoogle Scholar
  216. McGuffin, P., Rijsdijk, F., Andrew, M., Sham, P., Katz, R., & Cardno, A. (2003). The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Archives of General Psychiatry, 60, 497–502. doi: 10.1001/archpsyc.60.5.497.PubMedGoogle Scholar
  217. McIntyre, R. S., Soczynska, J. K., Bottas, A., Bordbar, K., Konarski, J. Z., & Kennedy, S. H. (2006). Anxiety disorders and bipolar disorder: A review. Bipolar Disorders, 8, 665–676. doi: 10.1111/j.1399-5618.2006.00355.x.PubMedGoogle Scholar
  218. McTavish, S. F., McPherson, M. H., Harmer, C. J., Clark, L., Sharp, T., Goodwin, G. M., et al. (2001). Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness. The British Journal of Psychiatry, 179, 356–360. doi: 10.1192/bjp.179.4.356.PubMedGoogle Scholar
  219. Mennuti, R. B., Christner, R. W., & Freeman, A. (Eds.). (2012). Cognitive-behavioral interventions in educational settings: A handbook for practice––second edition. New York, NY: Routledge.Google Scholar
  220. Merikangas, K. R., Jin, R., He, J.–. P., Kessler, R. C., Lee, S., Sampson, N. A., et al. (2011). Prevalence and correlates of bipolar spectrum disorder in the World Mental Health survey initiative. Archives of General Psychiatry, 68, 241–251. doi: 10.1001/archgenpsychiatry.2011.12.PubMedGoogle Scholar
  221. Merikangas, K. R., & Pato, M. (2009). Recent developments in the epidemiology of bipolar disorder in adults and children: Magnitude, correlates, and future directions. Clinical Psychology: Science and Practice, 16, 121–133. doi: 10.1111/j.1468-2850.2009.01152.x.Google Scholar
  222. Merrell, K. W. (2008). Behavioral, social, and emotional assessment of children and adolescents (3rd ed.). New York, NY: Lawrence Erlbaum Associates.Google Scholar
  223. Meyer, S. E., & Carlson, G. A. (2010). Development, age of onset, and phenomenology in bipolar disorder. In D. J. Miklowitz & D. Cicchetti (Eds.), Understanding bipolar disorder: A developmental psychopathology perspective (pp. 35–66). New York, NY: Guilford Press.Google Scholar
  224. Mick, E., Biederman, J., Pandina, G., & Faraone, S. V. (2003). A preliminary meta-analysis of the Child Behavior Checklist in pediatric bipolar disorder. Biological Psychiatry, 53, 1021–1027. doi: 10.1016/S0006-3223(03)00234-8.PubMedGoogle Scholar
  225. Miklowitz, D. J. (2008). Bipolar disorder: A family-focused treatment approach. New York, NY: Guilford Press.Google Scholar
  226. Miklowitz, D. J., Axelson, D. A., Birmaher, B., George, E. L., Taylor, D. O., Schneck, C. D., et al. (2008). Family-focused treatment for adolescents with bipolar disorder: Results of a 2-year randomized trial. Archives of General Psychiatry, 65, 1053–1061. doi: 10.1001/archpsyc.65.9.1053.PubMedGoogle Scholar
  227. Miklowitz, D. J., Chang, K. D., Taylor, D. O., George, E. L., Singh, M. K., Schneck, C. D., et al. (2011). Early psychosocial intervention for youth at risk for bipolar I or II disorder: A one-year treatment development trial. Bipolar Disorders, 13, 67–75. doi: 10.1111/j.1399-5618.2011.00890.x.PubMedGoogle Scholar
  228. Miklowitz, D. J., George, E. L., Richards, J. A., Simoneau, T. L., & Suddath, R. L. (2003). A randomized study of family-focused psychoeducation and pharmacotherapy in the outpatient management of bipolar disorder. Archives of General Psychiatry, 60, 904–912. doi: 10.1001/archpsyc.60.9.904.PubMedGoogle Scholar
  229. Miklowitz, D. J., Goodwin, G. M., Bauer, M. S., & Geddes, J. R. (2008). Common and specific elements of psychosocial treatments for bipolar disorder: A survey of clinicians participating in randomized trials. Journal of Psychiatric Practice, 14, 77–85. doi: 10.1097/01.pra.0000314314.94791.c9.PubMedGoogle Scholar
  230. Miklowitz, D. J., & Johnson, S. L. (2009). Social and familial factors in the course of bipolar disorder: Basic processes and relevant interventions. Clinical Psychology: Science and Practice, 16, 281–296. doi: 10.1111/j.1468-2850.2009.01166.x.Google Scholar
  231. Miklowitz, D. J., Otto, M. W., Frank, E., Reilly-Harrington, N. A., Wisniewski, S. R., Kogan, J. N., et al. (2007). Psychosocial treatments for bipolar depression: A 1-year randomized trial from the Systematic Treatment Enhancement Program. Archives of General Psychiatry, 64, 419–427. doi: 10.1001/archpsyc.64.4.419.PubMedGoogle Scholar
  232. Miller, I. W., Uebelacker, L. A., Keitner, G. I., Ryan, C. E., & Solomon, D. A. (2004). Longitudinal course of bipolar I disorder. Comprehensive Psychiatry, 45, 431–440. doi: 10.1016/j.comppsych.2004.07.005.PubMedGoogle Scholar
  233. Mockenhaupht, M., Viboud, C., Dunant, A., Naldi, L., Halevy, S., Bavinck, J. N. B., et al. (2008). Stevens-Johnson syndrome and toxic epidermal necrolysis: Assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. Journal of Investigative Dermatology, 128, 35–44. doi: 10.1038/sj.jiid.5701033.Google Scholar
  234. Mondimore, F. M. (2006). Bipolar disorder: A guide for patients and families (2nd ed.). Baltimore, MD: Johns Hopkins Press Health.Google Scholar
  235. Moor, S., Crowe, M., Luty, S., Carter, J., & Joyce, P. R. (2012). Effects of comorbidity and early age of onset in young people with bipolar disorder on self harming behavior and suicide attempts. Journal of Affective Disorders, 136, 1212–1215. doi: 10.1016/j.jad.2011.10.018.PubMedGoogle Scholar
  236. Moreno, C., Laje, G., Blanco, C., Jiang, H., Schmidt, A. B., & Olfson, M. (2007). National trends in the outpatient diagnosis and treatment of bipolar disorder in youth. Archives of General Psychiatry, 64, 1032–1039. doi: 10.1001/archpsyc.64.9.1032.PubMedGoogle Scholar
  237. Morgan, V. A., Mitchell, P. B., & Jablensky, A. V. (2005). The epidemiology of bipolar disorder: Sociodemographic, disability and service utilization data from the Australian National Study of Low Prevalence (Psychotic) Disorders. Bipolar Disorders, 7, 326–337. doi: 10.1111/j.1399-5618.2005.00229.x.PubMedGoogle Scholar
  238. Morris, C. D., Miklowitz, D. J., & Waxmonsky, J. A. (2007). Family-focused treatment for bipolar disorder in adults and youth. Journal of Clinical Psychology: In Session, 63, 433–445. doi: 10.1002/jclp.20359.PubMedGoogle Scholar
  239. Morris, R. J., & Mather, N. (Eds.). (2008). Evidence-based interventions for students with learning and behavioral challenges. Mahwah, NJ: Lawrence Erlbaum and Associates.PubMedGoogle Scholar
  240. Morriss, R., Scott, J., Paykel, E., Bentall, R., Hayhurst, H., & Johnson, T. (2007). Social adjustment based on reported behaviour in bipolar affective disorder. Bipolar Disorders, 9, 53–62. doi: 10.1111/j.1399-5618.2007.00343.x.PubMedGoogle Scholar
  241. Mortensen, P. B., Pedersen, C. B., Melbye, M., Mors, O., & Ewald, H. (2003). Individual and familial risk factors for bipolar affective disorders in Denmark. Archives of General Psychiatry, 60, 1209–1215. doi: 10.1001/archpsyc.60.12.1209.PubMedGoogle Scholar
  242. Mundo, E., Cattaneo, E., Russo, M., & Altamura, A. C. (2006). Clinical variables related to antidepressant-induced mania in bipolar disorder. Journal of Affective Disorders, 92, 227–230. doi: 10.1016/j.jad.2006.01.028.PubMedGoogle Scholar
  243. Narrow, W. E., Rae, D. S., Robins, L. N., & Regier, D. A. (2002). Revised prevalence estimates of mental disorders in the United States: Using a clinical significance criterion to reconcile 2 surveys’ estimates. Archives of General Psychiatry, 59, 115–123. doi: 10.1001/archpsyc.59.2.115.PubMedGoogle Scholar
  244. National Institute of Mental Health. (2001). National Institute of Mental Health research roundtable on prepubertal bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 871–878. doi: 10.1097/00004583-200108000-00007.Google Scholar
  245. National Institute of Mental Health. (2008). Bipolar disorder. Bethesda, MD: Author. Retrieved April 26, 2009, from http://www.nimh.nih.gov/health/publications/bipolar-disorder/complete-index.shtml#pub15
  246. Nery-Fernandes, F., Quarantini, L. C., Guimarães, J. L., de Oliveira, I. R., Koenen, K. C., Kapczinski, F., et al. (2012). Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder? Journal of Affective Disorders, 136, 1082–1087. doi: 10.1016/j.jad.2011.10.046.PubMedGoogle Scholar
  247. Nieto, R. G., & Castellanos, F. X. (2011). A meta-analysis of neuropsychological functioning in patients with early onset schizophrenia and pediatric bipolar disorder. Journal of Clinical Child and Adolescent Psychology, 40, 266–280. doi: 10.1080/15374416.2011.546049.PubMedGoogle Scholar
  248. Nivoli, A. M. A., Colom, F., Murru, A., Pacchiarotti, I., Castro-Loli, P., Gonález-Pinto, A., et al. (2010). New treatment guidelines for acute bipolar depression: A systematic review. Journal of Affective Disorders, 129, 14–26. doi: 10.1016/j.jad2010.05.018.PubMedGoogle Scholar
  249. Novick, D. M., Swartz, H. A., & Frank, E. (2010). Suicide attempts in bipolar I and bipolar II disorder: A review and meta-analysis of the evidence. Bipolar Disorders, 12, 1–9. doi: 10.1111/j.1399-5618.2009.00786.x.PubMedGoogle Scholar
  250. O’Neill, R. E., Horner, R. H., Albin, R. W., Sprague, J. R., Storey, K., & Newton, J. S. (1997). Functional assessment and program development for problem behavior: A practical handbook (2nd ed.). Pacific Grove, CA: Brooks/Cole.Google Scholar
  251. Öngür, D., Jensen, J. E., Prescot, A. P., Caitlin, S., Lundy, M., Cohen, B. M., et al. (2008). Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biological Psychiatry, 64, 718–726. doi: 10.1016/j.biopsych.2008.05.014.PubMedGoogle Scholar
  252. Papolos, J., Hatton, M. J., Norelli, S., Garcia, C. E., & Smith, A. M. (2002). The educational issues of students with bipolar disorder. Retrieved from www.bipolarchild.com
  253. Papolos, D., Hennen, J., & Cockerham, M. S. (2005). Factors associated with parent-reported suicide threats by children and adolescents with community-diagnosed bipolar disorder. Journal of Affective Disorders, 86, 267–275. doi: 10.1016/j.jad.2005.02.012.PubMedGoogle Scholar
  254. Papolos, D., Hennen, J., Cockerham, M. S., & Lachman, H. (2007). A strategy for identifying phenotypic subtypes: Concordance of symptom dimensions between sibling pairs who met screening criteria for a genetic linkage study of childhood-onset bipolar disorder using the Child Bipolar Questionnaire. Journal of Affective Disorders, 99, 27–36. doi: 10.1016/j.jad.2006.08.014.PubMedGoogle Scholar
  255. Papolos, D., Hennen, J., Cockerham, M. S., Thode, H. C., & Youngstrom, E. (2006). The child bipolar questionnaire: A dimensional approach to screening for pediatric bipolar disorder. Journal of Affective Disorders, 95, 149–158. doi: 10.1016/j.jad.2006.03.026.PubMedGoogle Scholar
  256. Papolos, D., Mattis, S., Golshan, S., & Molay, F. (2009). Fear of harm, a possible phenotype of pediatric bipolar disorder: A dimensional approach to diagnosis for genotyping psychiatric syndromes. Journal of Affective Disorders, 118, 28–38. doi: 10.1016/j.jad.2009.06.016.PubMedGoogle Scholar
  257. Papolos, D., & Papolos, J. (2006). The bipolar child: The definitive and reassuring guide to childhood’s most misunderstood disorder. New York, NY: Broadway.Google Scholar
  258. Patel, N. C., DelBello, M. P., Keck, P. E., & Strakowski, S. M. (2006a). Phenomenology associated with age at onset in patients with bipolar disorder at their first psychiatric hospitalization. Bipolar Disorders, 8, 91–94. doi: 10.1111/j.1399-5618.2006.00247.x.PubMedGoogle Scholar
  259. Patel, N. C., DelBello, M. P., Keck, P. E., & Strakowski, S. M. (2005). Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 15, 938–946. doi: 10.1089/cap.2005.15.938.PubMedGoogle Scholar
  260. Patel, N. C., DelBello, M. P., Keck, P. E., & Strakowski, S. M. (2006b). Ethnic differences in symptom presentation of youths with bipolar disorder. Bipolar Disorders, 8, 95–99. doi: 10.1111/j.1399-5618.2006.00279.x.PubMedGoogle Scholar
  261. Pavuluri, M. N. (2008). What works for bipolar kids: Help and hope for parents. New York, NY: Guilford Press.Google Scholar
  262. Pavuluri, M. N., Birmaher, B., & Naylor, M. W. (2005). Pediatric bipolar disorder: A review of the past 10 years. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 846–871. doi: 10.1097/01.chi.0000170554.23422.c1.PubMedGoogle Scholar
  263. Pavuluri, M. N., Graczyk, P. A., Henry, D. B., Carbray, J. A., Heidenreich, J., & Miklowitz, D. J. (2004a). Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: Development and preliminary results. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 528–537. doi: 10.1097/00004583-200405000-00006.PubMedGoogle Scholar
  264. Pavuluri, M. N., Graczyk, P. A., Henry, D. B., et al. (2004b). RAINBOW: Two programs combined may be better than one for pediatric BD. The Brown University Child and Adolescent Behavior Letter, 20(7), 5–7.Google Scholar
  265. Pavuluri, M. N., Henry, D. B., Moss, M., Mohammed, T., Carbray, J. A., & Sweeney, J. A. (2009). Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 19, 75–82. doi: 10.1089/cap.2008.0107.PubMedGoogle Scholar
  266. Pavuluri, M. N., Henry, D., Devineni, B., Carbray, J., & Birmaher, B. (2006). Child mania rating scale: Development, reliability and validity. Journal of American Academy of Child and Adolescent Psychiatry, 45, 550–560. doi: 10.1097/01.chi.0000205700.40700.50.PubMedGoogle Scholar
  267. Pavuluri, M. N., Henry, D. B., Nadimpalli, S. S., O’Connor, M. M., & Sweeney, J. A. (2006). Biological risk factors in pediatric bipolar disorder. Biological Psychiatry, 60, 936–941. doi: 10.1016/j.biopsych.2006.04.002.PubMedGoogle Scholar
  268. Pavuluri, M. N., Herbener, E. S., & Sweeney, J. A. (2004). Psychotic symptoms in pediatric bipolar disorder. Journal of Affective Disorders, 80, 19–28. doi: 10.1016/S0165-0327(03)00053-3.PubMedGoogle Scholar
  269. Pavuluri, M. N., O’Connor, M. M., Harral, E. M., Moss, M., & Sweeney, J. A. (2006). Impact of neurocognitive function on academic difficulties in pediatric bipolar disorder: A clinical translation. Biological Psychiatry, 60, 951–956. doi: 10.1016/j.biopsych.2006.03.027.PubMedGoogle Scholar
  270. Pavuluri, M. N., Schenkel, L. S., Aryal, S., Harral, E. M., Hill, S. K., Herbener, E. S., et al. (2006). Neurocognitive function in unmedicated manic and medicated euthymic pediatric bipolar patients. The American Journal of Psychiatry, 163, 286–293. doi: 10.1176/appi.ajp.163.2.286.PubMedGoogle Scholar
  271. Pavuluri, M. N., West, A., Hill, S. K., Jindal, K., & Sweeney, J. A. (2009). Neurocognitive function in pediatric bipolar disorder: 3-year follow-up shows cognitive development lagging behind healthy youths. Journal of the American Child and Adolescent Psychiatry, 48, 299–307. doi: 10.1097/CHI.0b013e318196b907.Google Scholar
  272. Pfeifer, J. C., Kowatch, R. A., & DelBello, M. P. (2010). Pharmacotherapy of bipolar disorder in children and adolescents: Recent progress. CNS Drugs, 24, 575–593. doi: 10.2165/11533110-000000000-00000.PubMedGoogle Scholar
  273. Pfeifer, J. C., Welge, J., Strakowski, S. M., Adler, C. M., & DelBello, M. P. (2008). Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 1289–1298. doi:10.1097/CHI.0b013e318185d299.PubMedGoogle Scholar
  274. Pichot, P. (2006). Tracing the origins of bipolar disorder: From Falret to DSM-IV and ICD-10. Journal of Affective Disorders, 96, 145–148. doi: 10.1016/j.jad.2006.05.031.PubMedGoogle Scholar
  275. Pini, S., de Queiroz, V., Pagnin, D., Pezawas, L., Angst, J., Cassano, G. B., et al. (2005). Prevalence and burden of bipolar disorders in European countries. European Neuropsychopharmacology, 15, 425–434. doi: 10.1016/j.euroneuro.2005.04.011.PubMedGoogle Scholar
  276. Plante, D. T., & Winkelman, J. W. (2008). Sleep disturbance in bipolar disorder: Therapeutic implications. The American Journal of Psychiatry, 165, 830–843. doi: 10.1176/appi.ajp.2008.08010077.PubMedGoogle Scholar
  277. Pope, M., Dudley, R., & Scott, J. (2007). Determinants of social functioning in bipolar disorder. Bipolar Disorders, 9, 38–44. doi: 10.1111/j.1399-5618.2007.00323.x.PubMedGoogle Scholar
  278. Post, R. M.(1992). Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. The American Journal of Psychiatry, 149, 999–1010. Retrieved from http://ajp.psychiatryonline.org.PubMedGoogle Scholar
  279. Post, R. M., & Leverich, G. S. (2006). The role of psychosocial stress in the onset and progression of bipolar disorder and its comorbidities: The need for earlier and alternative modes of therapeutic intervention. Development and Psychopathology, 18, 1181–1211. doi: 10.1017/S0954579406060573.PubMedGoogle Scholar
  280. Post, R. M., Leverich, G. S., Kupka, R. W., Keck, P. E., McElroy, S., Altshuler, L. L., et al. (2010). Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. The Journal of Clinical Psychiatry, 71, 864–872. doi: 10.4088/JCP.08m04994yel.PubMedGoogle Scholar
  281. Powell, S. B., Young, J. W., Ong, J. C., Caron, M. G., & Geyer, M. A. (2008). Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behavioural Pharmacology, 19, 562–565. doi: 10.1097/FBP.0b013e32830dc110.PubMedGoogle Scholar
  282. Preston, J., & Johnson, J. (2008). Clinical psychopharmacology made ridiculously simple (5th ed.). Miami, FL: MedMaster.Google Scholar
  283. Quanbeck, C. D., Stone, D. C., Scott, C. L., McDermott, B. E., Altshuler, L. L., & Frye, M. A. (2004). Clinical and legal correlates of inmates with bipolar disorder at time of criminal arrest. The Journal of Clinical Psychiatry, 65, 198–203. doi: 10.4088/JCP.v65n0209.PubMedGoogle Scholar
  284. Raman, R. P. B., Shesadri, S. P., Reddy, Y. C. J., Girimaji, S. C., Srinath, S., & Raghunandan, V. N. G. P. (2007). Is bipolar II disorder misdiagnosed as major depressive disorder in children? Journal of Affective Disorders, 98, 263–266. doi: 10.1016/j.jad.2006.08.006.Google Scholar
  285. Reichart, C. G., & Nolen, W. A. (2004). Earlier onset of bipolar disorder in children by antidepressants or stimulants? An hypothesis. Journal of Affective Disorders, 78, 81–84. doi: 10.1016/S0165-0327(02)00180-5.PubMedGoogle Scholar
  286. Reichart, C. G., van der Ende, J., Hillegers, M. H. J., Wals, M., Bongers, I. L., Nolen, W. A., et al. (2007). Perceived parental rearing of bipolar offspring. Acta Psychiatrica Scandinavica, 115, 21–28. doi: 10.1111/j.1600-0447.2006.00838.x.PubMedGoogle Scholar
  287. Reichart, C. G., van der Ende, J., Wals, M., Hillegers, M. H. J., Nolen, W. A., Ormel, J., et al. (2007). Social functioning of bipolar offspring. Journal of Affective Disorders, 98, 207–213. doi: 10.1016/j.jad.2006.07.018.PubMedGoogle Scholar
  288. Reikert, K. A., & Drotar, D. (2000). Adherence to medical treatment in pediatric chronic illness: Critical issues and unanswered questions. In D. Drotar (Ed.), Promoting adherence to treatment in pediatric chronic illness: Concepts, methods, and interventions (pp. 201–231). Mahwah, NJ: Erlbaum.Google Scholar
  289. Renou, S., Hergueta, T., Flament, M., Mouren-Simeoni, M. C., & Lecrubier, Y. (2004). Diagnostic structured interviews in child and adolescent’s psychiatry. Encephale, 30, 122–134. doi: 10.1016/S0013-7006(04)95422-X.PubMedGoogle Scholar
  290. Rich, B. A., Fromm, S. J., Berghorst, L. H., Dickstein, D. P., Brotman, M. A., Pine, D. S., et al. (2008). Neural connectivity in children with bipolar disorder: Impairment in the face emotion processing circuit. Journal of Child Psychology and Psychiatry, 49, 88–96. doi: 10.1111/j.1469-7610.2007.01819.x.PubMedGoogle Scholar
  291. Rich, B. A., Vinton, D. T., Roberson-Nay, R., Hommer, R. E., Berghorst, L. H., McClure, E. B., et al. (2006). Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder. PNAS, 103(23), 8900–8905. doi: 10.1073/pnas.0603246103.PubMedGoogle Scholar
  292. Robins, L., & Price, R. (1991). Adult disorders predicted by childhood conduct problems: Results for the NIMH epidemiologic catchment area project. Psychiatry, 54, 116–132. http://ajp.psychiatryonline.org/journal.aspx?journalid=13.PubMedGoogle Scholar
  293. Romero, S., Birmaher, B., Axelson, D., Goldstein, T., Goldstein, B. I., Gill, M. K., et al. (2009). Prevalence and correlates of physical and sexual abuse in children and adolescents with bipolar disorder. Journal of Affective Disorders, 112, 144–150. doi: 10.1016/j.jad.2008.04.005.PubMedGoogle Scholar
  294. Roybal, D. J., Chang, K. D., Chen, M. C., Howe, M. E., Gotlib, I. H., & Singh, M. K. (2011). Characterization and factors associated with sleep quality in adolescents with bipolar I disorder. Child Psychiatry and Human Development, 42, 724–740. doi: 10.1007/s10578-011-0239-0.PubMedGoogle Scholar
  295. Sachs, G. S., Baldassano, C. F., Truman, C. J., & Guille, C. (2000). Comorbidity of attention deficit hyperactivity disorder with early- and late-onset bipolar disorder. The American Journal of Psychiatry, 157, 466–468. doi: 10.1176/appi.ajp.157.3.466.PubMedGoogle Scholar
  296. Sakai, T., Oshima, A., Nozaki, Y., Ida, I., Haga, C., Akiyama, H., et al. (2008). Changes in density of calcium-binding-protein-immunoreactive GABAergic neurons in prefrontal cortex in schizophrenia and bipolar disorder. Neuropathology, 28, 143–150. doi: 10.1111/j.1440-1789.2007.00867.x.PubMedGoogle Scholar
  297. Sala, R., Axelson, D. A., Castro-Fornieles, J., Goldstein, T. R., Ha, W., Liao, F., et al. (2010). Comorbid anxiety in children and adolescents with bipolar spectrum disorders: Prevalence and clinical correlates. The Journal of Clinical Psychiatry, 71, 1344–1350. doi: 10.4088/JCP.09m05845gre.PubMedGoogle Scholar
  298. Schenkel, L. S., Marlow-O’Connor, M., Moss, M., Sweeney, J. A., & Pavuluri, M. N. (2008). Theory of mind and social inference in children and adolescents with bipolar disorder. Psychological Medicine, 38, 791–800. doi: 10.1017/S0033291707002541.PubMedGoogle Scholar
  299. Serene, J. A., Ashtari, M., Szeszko, P. R., & Kumra, S. (2007). Neuroimaging studies of children with serious emotional disturbances: A selected review. The Canadian Journal of Psychiatry/La Revue Canadienne de Psychiatrie, 52, 135–145. http://publications.cpa-apc.org/browse/sections/0.Google Scholar
  300. Serretti, A., & Mandelli, L. (2008). The genetics of bipolar disorder: Genome ‘hot regions,’ genes, new potential candidates and future directions. Molecular Psychiatry, 13, 742–771. doi: 10.1038/mp.2008.29.PubMedGoogle Scholar
  301. Shen, G. H. C., Alloy, L. B., Abramson, L. Y., & Sylvia, L. G. (2008). Social rhythm regularity and the onset of affective episodes in bipolar spectrum individuals. Bipolar Disorders, 10, 520–529. doi: 10.1111/j.1399-5618.2008.00583.x.PubMedGoogle Scholar
  302. Silverstone, T. (1985). Dopamine in manic depressive illness. A pharmacological synthesis. Journal of Affective Disorders, 8, 225–231. doi: 10.1016/0165-0327(85)90020-5.PubMedGoogle Scholar
  303. Singh, M. K., Pfeifer, J. C., Barzman, D., Kowatch, R. A., & DelBello, M. P. (2007). Pharmacotherapy for child and adolescent mood disorder. Psychiatric Annals, 37, 465–476. http://www.healio.com/psychiatry.Google Scholar
  304. Smarty, S., & Findling, R. L. (2007). Psychopharmacology of pediatric bipolar disorder: A review. Psychopharmacology, 191, 39–54. doi: 10.1007/s00213-006-0569-y.PubMedGoogle Scholar
  305. Somanath, C. P., Jain, S., & Reddy, Y. C. J. (2002). A family study of early-onset bipolar I disorder. Journal of Affective Disorders, 70, 91–94. doi: 10.1016/S0165-0327(00)00372-4.PubMedGoogle Scholar
  306. Sopko, K. M. (2006). School mental health services in the United States. InForum, 1–9. http://www.projectforum.org
  307. Soutullo, C. A., Chang, K. D., Díez-Suárez, A., Figueroa-Quintana, A., Escamilla-Canales, I., Rapado-Castro, M., et al. (2005). Bipolar disorder in children and adolescents: International perspective on epidemiology and phenomenology. Bipolar Disorders, 7, 497–506. doi: 10.1111/j.1399-5618.2005.00262.x.PubMedGoogle Scholar
  308. Squires, J. Bricker, D. & Twombly, E. (2002). Ages and Stages Questionnaires: Social and Emotional. Baltimore, MD: Brookes Publishing.PubMedGoogle Scholar
  309. Staton, D., Volness, L. J., & Beatty, W. W. (2008). Diagnosis and classification of pediatric bipolar disorder. Journal of Affective Disorders, 105, 205–212. doi: 10.1016/j.jad.2007.05.015.PubMedGoogle Scholar
  310. Stoddard-Dare, P., Mallett, C. A., & Boitel, C. (2011). Association between mental health disorders and juveniles’ detention for a personal crime. Child and Adolescent Mental Health, 16, 208–213. doi: 10.1111/j.1475-3588.2011.00599.x.Google Scholar
  311. Strawn, J. R., Adler, C. M., Fleck, D. E., Hanseman, D., Maue, D. K., Bitter, S., et al. (2010). Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder. Early Intervention in Psychiatry, 4, 169–173. doi: 10.1111/j.1751-7893.2010.00173.x.PubMedGoogle Scholar
  312. Sublette, M. E., Oquendo, M. A., & Mann, J. J. (2006). Rational approaches to neurobiologic study of youth at risk for bipolar disorder and suicide. Bipolar Disorders, 8, 526–542. doi: 10.1111/j.1399.5618.2006.00372.x.Google Scholar
  313. Sullivan, A. E., & Miklowitz, D. J. (2010). Family functioning among adolescents with bipolar disorder. Journal of Family Psychology, 24, 60–67. doi: 10.1037/a001813.PubMedGoogle Scholar
  314. Tillman, R., & Geller, B. (2006). Controlled study of switching from attention-deficit/hyperactivity disorder to a prepubertal and early adolescent bipolar I disorder phenotype during 6-year prospective follow-up: Rate, risk, and predictors. Development and Psychopathology, 18, 1037–1053. doi: 10.1017/S095457940606051.PubMedGoogle Scholar
  315. Townsend, L. D., Demeter, C. A., Youngstrom, E., Drotar, D., & Findling, R. L. (2007). Family conflict moderates response to pharmacological intervention in pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 17, 843–851. doi: 10.1089/cap.2007.0046.PubMedGoogle Scholar
  316. Tsuang, M. T., & Faraone, S. V. (1990). The genetics of mood disorders. Baltimore, MD: John Hopkins University Press.Google Scholar
  317. U.S. Department of Education. (2006). 34 C. F. R. Parts 300 and 301: Assistance to states for the education of children with disabilities; Final rule. Federal Register, 71, 46540–46845. www.federalregister.gov.Google Scholar
  318. Valtonen, H. M., Suominen, K., Mantere, O., Lappämäki, S., Arvilommi, P., & Isometsä, E. (2007). Suicidal behaviour during different phases of bipolar disorder. Journal of Affective Disorders, 97, 101–107. doi: 10.1016/j.jad.2006.05.033.PubMedGoogle Scholar
  319. Van Meter, A. R., Moreira, A. L. R., & Youngstrom, E. A. (2011). Meta-analysis of epidemiologic studies of pediatric bipolar disorder. The Journal of Clinical Psychiatry, 72, 1250–1256. doi: 10.4088/JCP.10m06290.PubMedGoogle Scholar
  320. Van Meter, A., Youngstrom, E. A., Youngstrom, J. K., Feeny, N. C., & Findling, R. L. (2011). Examining the validity of cyclothymic disorder in a youth sample. Journal of Affective Disorders, 132, 55–63. doi: 10.1016/j.jad.2011.02.004.PubMedGoogle Scholar
  321. West, A. E., Henry, D. B., & Pavuluri, M. N. (2007). Maintenance model of integrated psychosocial treatment in pediatric bipolar disorder: A pilot feasibility study. Journal of the American Academy of Child and Adolescent Psychiatry, 46, 205–212. doi: 10.1097/01.chi.0000246068.85577.d7.PubMedGoogle Scholar
  322. West, A. E., Jacobs, R. H., Westerholm, R., Adabel, L., Carbray, J., Heidenreich, J., et al. (2009). Child and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: Pilot study of group treatment format. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 18, 239–246. www.cacap-acpea.org/.PubMedGoogle Scholar
  323. West, A. E., Weinstein, S. M., Celio, C. I., Henry, D., & Pavuluri, M. N. (2011). Co-morbid disruptive behavior disorder and aggression predict functional outcomes and differential response to risperidone versus divalproex in pharmacotherapy for pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 21, 545–553. doi: 10.1089/cap.2010.0140.PubMedGoogle Scholar
  324. Wilens, T. E., Biederman, J., Adamson, J. J., Henin, A., Sgambati, S., Gignac, M., et al. (2008). Further evidence of an association between adolescent bipolar disorder with smoking and substance use disorders: A controlled study. Drug and Alcohol Dependence, 95, 188–198. doi: 10.1016/j.drugalcdep.2007.12.016.PubMedGoogle Scholar
  325. Wiste, A. K., Arango, V., Ellis, S. P., Mann, J. J., & Underwood, M. D. (2008). Norepinephrine and serotonin imbalance in the locus coeruleus in bipolar disorder. Bipolar Disorders, 10, 349–359. doi: 10.1111/j.1399.5618.2007.00528.x.PubMedGoogle Scholar
  326. World Health Organization. (2001). The World Health Report 2001. Mental health: New understanding, new hope. Geneva, Switzerland: Author. http://www.who.int/whr/2001/en/.
  327. Wozniak, J., Biederman, J., Faraone, S. V., Blier, H., & Monuteaux, M. C. (2001). Heterogeneity of childhood conduct disorder: Further evidence of a subtype of conduct disorder linked to bipolar disorder. Journal of Affective Disorders, 64, 121–131. doi: 10.1016/S0165-0327(00)00217-2.Google Scholar
  328. Wozniak, J., Biederman, J., Mick, E., Waxmonsky, J., Hantsoo, L., Best, C., et al. (2007). Omega-3 fatty acid monotherapy for pediatric bipolar disorder: A prospective open-label trial. European Neuropsychopharmacology, 17, 440–447. doi: 10.1016/j.euroneuro.2006.11.006.PubMedGoogle Scholar
  329. Wozniak, J., Petty, C. R., Schreck, M., Moses, A., Faraone, S. V., & Biederman, J. (2011). High level of persistence of pediatric bipolar-I disorder from childhood onto adolescent years: A four year prospective longitudinal follow-up study. Journal of Psychiatric Research, 45, 1273–1282. doi: 10.1016/j.jpsychires.2010.10.006.PubMedGoogle Scholar
  330. Wozniak, J., Spencer, T., Biederman, J., Kwon, A., Monuteaux, M., Rettew, J., et al. (2004). The clinical characteristics of unipolar vs. bipolar major depression in ADHD youth. Journal of Affective Disorders, 82(suppl), 59–69.  10.1016/j.jad.2004.05.013.Google Scholar
  331. Yatham, L. N., Liddle, P. F., Lam, R. W., Shiah, I. S., Lane, C., Stoessl, A. J., et al. (2002). PET study of the effects of valproate on dopamine D(2) receptors in neuroleptic- and mood-stabilizer-naive patients with nonpsychotic mania. The American Journal of Psychiatry, 159, 1718–1723. doi: 10.1176/appi.ajp.159.10.1718.PubMedGoogle Scholar
  332. Yen, C.-F., Chen, C.-S., Ko, C.-H., Yen, J.-Y., & Huang, C.-F. (2007). Changes in insight among patients with bipolar I disorder: A 2-year prospective study. Bipolar Disorders, 9, 238–242. doi: 10.1111/j.1399-5618.2007.00407.x.PubMedGoogle Scholar
  333. Yerevanian, B., Koek, R. J., & Mintz, J. (2007). Bipolar pharmacotherapy and suicidal behavior part 1: Lithium, divalproex and carbamazepine. Journal of Affective Disorders, 103, 5–11. doi: 10.1016/j.jad.2007.05.019.PubMedGoogle Scholar
  334. Yerevanian, B., Koek, R. J., Mintz, J., & Akiskal, H. S. (2007). Bipolar pharmacolotherapy and suicidal behavior part 2: The impact of antidepressants. Journal of Affective Disorders, 103, 13–21. doi: 10.1016/j.jad.2007.05.017.PubMedGoogle Scholar
  335. Young, M. E., & Fristad, M. A. (2007). Evidence based treatments for bipolar disorder in children and adolescents. Journal of Contemporary Psychotherapy, 37, 157–164. doi: 10.1007/s10879-007-9050-4.Google Scholar
  336. Youngstrom, E. A., Findling, R. L., Danielson, C. K., & Calabrese, J. R. (2001). Discriminative validity of parent report of hypomanic and depressive symtpoms on the General Behavior Inventory. Psychological Assessment, 13, 267–276. doi: 10.1037/1040-3590.13.2.267.PubMedGoogle Scholar
  337. Youngstrom, E. A., Findling, R. L., Calabrese, J. R., Gracious, B. L., Demeter, C., Bedoya, D. D., et al. (2004). Comparing the diagnostic accuracy of six potential screening instruments for bipolar disorder in youths aged 5 to 17 years. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 847–858. doi: 10.1097/01.chi.0000125091.35109.1e.PubMedGoogle Scholar
  338. Youngstrom, E. A., Findling, R. L., Youngstrom, J. K., & Calabrese, J. R. (2005). Toward an evidence-based assessment of pediatric bipolar disorder. Journal of Clinical Child and Adolescent Psychology, 34, 433–448. doi: 10.1207/s15374424jccp3403_4.PubMedGoogle Scholar
  339. Youngstrom, E. A., Birmaher, B., & Findling, R. L. (2008). Pediatric bipolar disorder: Validity, phenomenology, and recommendations for diagnosis. Bipolar Disorders, 10, 194–214. doi: 10.1111/j.1399-5618.2007.00563.x.PubMedGoogle Scholar
  340. Youngstrom, E. A., Frazier, T. W., Demeter, C., Calabrese, J. R., & Findling, R. L. (2008). Developing a 10-item mania scale from the Parent General Behavior Inventory for Children and Adolescents. The Journal of Clinical Psychiatry, 69, 831–839. doi: 10.4088/JCP.v69n0517.PubMedGoogle Scholar
  341. Youngstrom, E., Meyers, O., Demeter, C., Youngstrom, J., Morello, L., Piiparinen, R., et al. (2005). Comparing diagnostic checklists for pediatric bipolar disorder in academic and community mental health settings. Bipolar Disorders, 7, 507–517. doi: 10.1111/j.1399-5618.2005.00269.x.PubMedGoogle Scholar
  342. Youngstrom, E., Youngstrom, J. K., & Starr, M. (2005). Bipolar diagnoses in community mental health: Achenbach Child Behavior Checklist profiles and patterns of comorbidity. Biological Psychiatry, 58, 569–575. doi: 10.1016/j.biopsych.2005.04.004.PubMedGoogle Scholar
  343. Zito, J. M., Derivan, A. T., Kratochvil, C. J., Safer, D. J., Fegert, J. M., & Greenhill, L. L. (2008). Off-label psychopharmacologic prescribing for children: History supports close clinical monitoring. Child and Adolescent Psychiatry and Mental Health, 2, 24–35. doi: 10.1186/1753-2000-2-24.PubMedGoogle Scholar
  344. Zuckerman, M. (1999). Vulnerability to psychopathology: A biosocial model. Washington, DC: American Psychological Association.Google Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Shelley R. Hart
    • 1
  • Stephen E. Brock
    • 2
  • Ida Jeltova
    • 3
  1. 1.Bloomberg School of Public Health Department of Mental HealthJohns Hopkins UniversityBaltimoreUSA
  2. 2.Department of Special Education, RehabilitationSchool Psychology and Deaf Studies California State University, SacramentoSacramentoUSA
  3. 3.Graduate CenterCity University of New YorkNew YorkUSA

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