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High-Resolution Electron Crystallography of Membrane Proteins

  • Werner Kühlbrandt
Part of the Methods in Physiology Series book series (METHPHYS)

Abstract

For the foreseeable future, progress in determining high-resolution structures of membrane proteins will depend on crystallographic techniques. Until recently, x-ray crystallography seemed to be the only promising method. Progress with this technique, however, has not been as rapid as originally hoped because it is difficult to grow large and sufficiently well-ordered three-dimensional crystals. Electron crystallography of two-dimensional crystals is now a viable alternative that is particularly suitable for structural studies of membrane proteins because of their natural propensity to form two-dimensional arrays.

Keywords

Purple Membrane Tilt Axis Incident Electron Beam Dimensional Crystal Electron Crystallography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© American Physiological Society 1994

Authors and Affiliations

  • Werner Kühlbrandt

There are no affiliations available

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