Transmigration of Leukocytes

  • Brian Stein
  • Yeesim Khew-Goodall
  • Mathew Vadas
Part of the Methods in Physiology Series book series (METHPHYS)


Migration of cells through a vascular endothelial monolayer is an essential step in inflammation, and thus in host defense and healing. Migration of neutrophils is the most studied form, providing basis for understanding the migration of other cell types. Of the series of events involved in transmigration, this chapter will limit its scope to the process of moving across the endothelial monolayer, and refer briefly to events immediately surrounding that process. Other events and mediators, such as endothelial activation and firm adhesion and the selectins, integrins, and chemoattractants, are dealt with elsewhere in this volume.


Transendothelial Migration Endothelial Monolayer Firm Adhesion Endothelial Cell Monolayer Myosin Light Chain Phosphorylation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© American Physiological Society 2001

Authors and Affiliations

  • Brian Stein
  • Yeesim Khew-Goodall
  • Mathew Vadas

There are no affiliations available

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