Abstract
This case discusses the pharmacokinetic interaction between cyclosporine and St. John’s wort, resulting in renal failure. Cyclosporine is a cytochrome P450 3A4 and P-glycoprotein substrate and St. John’s wort is a 3A4 and P-glycoprotein inducer.
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Norvelle, H., Koerner, I.P. (2015). St. John: Not Such a Saint. In: Marcucci, C., et al. A Case Approach to Perioperative Drug-Drug Interactions. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7495-1_219
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DOI: https://doi.org/10.1007/978-1-4614-7495-1_219
Publisher Name: Springer, New York, NY
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