Pain on the Plane

Fatal Forty DDI: ginseng, warfarin, CYP2C9
  • Lei Wu
  • Kirk Lalwani


This case discusses a pharmacokinetic interaction between warfarin and ginseng resulting in the decreased anticoagulant effect of warfarin. Warfarin is a cytochrome P450 2C9 substrate and ginseng is a 2C9 inducer.


Pharmacokinetic Warfarin Gingseng Panax quinquefolius Cytochrome P450 CYP 2C9 CYP2C9 Induction Ginsenosides 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of RadiologyUSC Medical Center in Los AngelesLos AngelesUSA
  2. 2.Department of Anesthesiology and Perioperative MedicineOregon Health and Science UniversityPortlandUSA

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