Skip to main content

Quantitative Magnetic Resonance Analysis in the Assessment of Cardiac Diseases

  • Chapter
  • First Online:
Multi-Modality Atherosclerosis Imaging and Diagnosis

Abstract

Cardiac magnetic resonance (CMR) offers several acquisition techniques for accurate and highly reproducible quantitative assessment of global and regional ventricular function, blood flow, myocardial perfusion at rest and stress, necrotic and scarred myocardium, and heart iron load.

The ongoing clinical need for objective and accurate assessment of myocardial function and recent advances in CMR hardware and automated and semi-automated image analysis software resulted in significant improvements in image quality and a reduction in imaging time.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Pennell DJ, Sechtem UP, Higgins CB et al (2004) Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J 25:1940–1965

    Article  PubMed  Google Scholar 

  2. Shapiro EP, Rogers WJ, Beyar R et al (1989) Determination of left ventricular mass by magnetic resonance imaging in hearts deformed by acute infarction. Circulation 79:706–711

    Article  PubMed  CAS  Google Scholar 

  3. Barkhausen J, Ruehm SG, Goyen M et al (2001) MR evaluation of ventricular function: true fast imaging with steady-state precession versus fast low angle shot cine MR imaging-feasibility study. Radiology 219:264–269

    PubMed  CAS  Google Scholar 

  4. Plein S, Bloomer TN, Ridgway JP et al (2001) Steady state free precession magnetic resonance imaging of the heart: comparison with segmented k-space gradient-echo imaging. J Magn Reson Imaging 14:230–236

    Article  PubMed  CAS  Google Scholar 

  5. Kondo C, Caputo GR, Semelka R et al (1991) Right and left ventricular stroke volume measurements with velocity-encoded cine MR imaging: in vitro and in vivo validation. AJR Am J Roentgenol 157:9–16

    Article  PubMed  CAS  Google Scholar 

  6. Azhari H, Sideman S, Weiss JL et al (1990) Three-dimensional mapping of acute ischemic regions using MRI: wall thickening versus motion analysis. Am J Physiol 259:H1492–H1503

    PubMed  CAS  Google Scholar 

  7. Weintraub WS, Agarwal JB, Seeclaus PA et al (1983) Segmental wall motion score as a predictor of survival in coronary artery disease. Circulation 68:111–114

    Google Scholar 

  8. Lieberman AN, Weiss JL, Jugdutt BI et al (1981) Two dimensional echocardiography and infarct size: relationship of regional wall motion and thickening to the extent of myocardial infarction in the dog. Circulation 63:739–746

    Article  PubMed  CAS  Google Scholar 

  9. San Román JA, Candell-Riera J, Arnold R et al (2009) Quantitative analysis of left ventricular function as a tool in clinical research. Theoretical basis and methodology. Rev Esp Cardiol 62(5):535–551

    Article  PubMed  Google Scholar 

  10. Picano E, Lattanzi F, Orlandini A et al (1991) Stress echocardiography and the human factor: the importance of being expert. J Am Coll Cardiol 17:666–669

    Article  PubMed  CAS  Google Scholar 

  11. Nagel E, Lehmkuhl HB, Bocksch W et al (1999) Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress MRI: comparison with dobutamine stress echocardiography. Circulation 99:763–770

    Article  PubMed  CAS  Google Scholar 

  12. McVeigh ER, Zerhouni EA (1991) Noninvasive measurement of transmural gradients in myocardial strain with MR imaging. Radiology 180:677–683

    PubMed  CAS  Google Scholar 

  13. Bogaert J, Dymarkowski S, Taylor AM (2005) Clinical cardiac MRI. 1. Springer, Berlin

    Book  Google Scholar 

  14. Meier D, Maier S, Boesiger P (1988) Quantitative flow measurements on phantoms and on blood vessels with MR. Magn Reson Med 8:25–34

    Article  PubMed  CAS  Google Scholar 

  15. Sechtem U, Pflugfelder PW, Cassidy MM et al (1988) Mitral and aortic regurgitation: quantification of regurgitant volumes with cine MR imaging. Radiology 167:425–430

    PubMed  CAS  Google Scholar 

  16. Longmore DB, Klipstein RH, Underwood SR (1985) Dimensional accuracy of magnetic resonance studies of the heart. Lancet 1:1360–1362

    Article  PubMed  CAS  Google Scholar 

  17. Kondo C, Caputo GR, Semelka R et al (1991) Right and left ventricular stroke volume measurements with velocity encoded cine NMR imaging: in vivo and in vitro evaluation. AJR Am J Roentgenol 157:9–16

    Article  PubMed  CAS  Google Scholar 

  18. Gallagher KP, Osakada G, Matsuzaki M et al (1982) Myocardial blood flow and function with critical coronary stenosis in exercising dogs. Am J Physiol 243(5):698–707

    Google Scholar 

  19. Schwitter J, Nanz D, Kneifel S et al (2001) Assessment of myocardial perfusion in coronary artery disease by magnetic resonance. A comparison with positron emission tomography and coronary angiography. Circulation 103:2230–2235

    Article  PubMed  CAS  Google Scholar 

  20. Nagel E, Klein C, Paetsch I et al (2003) Magnetic resonance perfusion measurements for the noninvasive detection of coronary artery disease. Circulation 108:432–437

    Article  PubMed  Google Scholar 

  21. Nandalur KR, Dwamena BA, Choudhri AF et al (2007) Diagnostic performance of stress cardiac magnetic resonance imaging in the detection of coronary artery disease: a meta-analysis. J Am Coll Cardiol 50:1343–1353

    Article  PubMed  Google Scholar 

  22. Milles J, Van der Geest RJ, Jerosch-Herold M et al (2008) Fully automated motion correction in first-pass myocardial perfusion MR image sequences. IEEE Trans Med Imaging 27:1611–1621

    Article  PubMed  Google Scholar 

  23. Lee DC, Johnson NP (2009) Quantification of absolute myocardial blood flow by magnetic resonance perfusion imaging. JACC Cardiovasc Imaging 2:761–770

    Article  PubMed  Google Scholar 

  24. Kim RJ, Fieno DS, Parrish TB et al (1999) Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 100:1992–2002

    Article  PubMed  CAS  Google Scholar 

  25. Kim RJ, Wu E, Rafael A et al (2000) The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 343:1445–1453

    Article  PubMed  CAS  Google Scholar 

  26. Wu E, Ortiz JT, Tejedor P et al (2008) Infarct size by contrast enhanced cardiac magnetic resonance is a stronger predictor of outcomes than left ventricular ejection fraction or end-systolic volume index: prospective cohort study. Heart 94:730–736

    Article  PubMed  CAS  Google Scholar 

  27. Thomson LEJ, Kim RJ, Judd RM (2004) Magnetic resonance imaging for the assessment of myocardial viability. J Magn Reson Imaging 19:771–788

    Article  PubMed  Google Scholar 

  28. Masci PG, Ganame J, Strata E et al (2010) Myocardial salvage by CMR correlates with LV remodeling and early ST-segment resolution in acute myocardial infarction. JACC Cardiovasc Imaging 3(1):45–51

    Article  PubMed  Google Scholar 

  29. Liu P, Olivieri N (1994) Iron overload cardiomyopathies: new insights into an old disease. Cardiovasc Drugs Ther 8:101–110

    Article  PubMed  CAS  Google Scholar 

  30. Wood JC (2007) Magnetic resonance imaging measurement of iron overload. Curr Opin Hematol 14:183–190

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Filippo Cademartiri .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Maffei, E. et al. (2014). Quantitative Magnetic Resonance Analysis in the Assessment of Cardiac Diseases. In: Saba, L., Sanches, J., Pedro, L., Suri, J. (eds) Multi-Modality Atherosclerosis Imaging and Diagnosis. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7425-8_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-7425-8_6

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-7424-1

  • Online ISBN: 978-1-4614-7425-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics