Abstract
The immune-control hypothesis, as we explained in the Introduction, leads to a very different picture of HIV evolution in vivo than that of traditional population genetics. In this chapter, we compare the explanations for escapes derived from the two approaches.
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Notes
- 1.
If \(R_{\mbox{ eff.}} = 1 + s\) and s is small, then, up to an unimportant factor, ESA = \(1 - 1/(1 + s) \approx s\); see Part II, Chapter 20.
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Wick, W.D., Yang, O.O. (2013). Early and Late Escapes. In: War in the Body. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7294-0_6
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DOI: https://doi.org/10.1007/978-1-4614-7294-0_6
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