Simulating an HIV Infection In Vivo

  • W. David Wick
  • Otto O. Yang
Chapter

Abstract

When the HIV and CTL models are combined, we have gone beyond familiar textbook examples of biological modeling. Although mathematics provides insights into the predictions of the model (described in subsequent chapters), to some extent we must rely on computer simulation.

Keywords

Metaphor 

Bibliography

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    Wick WD, Gilbert PB, Self SG (2006) On modeling HIV and T cells in vivo: assessing casual estimators in vaccine trials. PLoS Comput Biol 2(6). dx.doi.org/10.1371/journal.pcbi.0020064Google Scholar
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    Wick WD, Yang OO, Corey L, Self SG (2005) How many HIV-1 infected target cells can a cytotoxic T-lymphocyte kill? J Virol 79:1379–1386CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • W. David Wick
    • 1
  • Otto O. Yang
    • 2
  1. 1.SeattleUSA
  2. 2.Geffen School of Medicine, Department of MedicineUCLA Medical CenterLos AngelesUSA

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