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Afterword: The RV144 Trial and the Current Status of HIV Vaccine Research

  • W. David Wick
  • Otto O. Yang
Chapter

Abstract

The long history of vaccine development, starting with observations about cowpox and smallpox, has been mainly empirical. The two biggest pioneers of modern vaccines, Salk and Sabin, were proponents of two competing strategies: kill or weaken the pathogen, and mimic infection without disease.

Keywords

Pretest Probability Uninfected Person Compete Strategy Modern Vaccine RV144 Trial 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Bibliography

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    Ioannidis JPA (2005) Why most published research findings are false. PLoS Med 2(8):e124. doi:10.137/journal/pmed.0020124Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • W. David Wick
    • 1
  • Otto O. Yang
    • 2
  1. 1.SeattleUSA
  2. 2.Geffen School of Medicine, Department of MedicineUCLA Medical CenterLos AngelesUSA

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