Fortification of Human Milk for Preterm Infants

  • Luigi CorvagliaEmail author
  • Elena Legnani
  • Arianna Aceti
  • Elisa Mariani
  • Giacomo Faldella
Part of the Nutrition and Health book series (NH)


Human milk is the best feeding choice for preterm infants, as it offers protection against sepsis and other infections (particularly diarrhoea and acute otitis media) [1] and against necrotizing enterocolitis (NEC) [2], thanks to its various bioactive and immunomodulatory components. Furthermore, human milk feeding is related to long-term improved neurocognitive development [3]. It has a beneficial role in facilitating and improving adaptation to extrauterine life; its components also have the effect of promoting psychomotor and behavioural development [4].


Preterm infants Nutrition Human milk Fortification Protein intake Growth 



American Academy of Pediatrics


Appropriate for gestational age


Arachidonic acid


Blood urea nitrogen


Docosahexaenoic acid


European Society of Pediatric Gastroenterology, Hepatology and Nutrition


Gestational age


Gastroesophageal reflux


Human milk fortifier


Low birth weight


Long-chain polyunsatured fatty acid


Medium-chain triglyceride


Necrotizing enterocolitis


Neonatal intensive care unit




Randomized controlled trial


Small for gestational age


Very low birth weight


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Luigi Corvaglia
    • 1
    Email author
  • Elena Legnani
    • 1
  • Arianna Aceti
    • 1
  • Elisa Mariani
    • 1
  • Giacomo Faldella
    • 1
  1. 1.Neonatology and Intensive Care Unit-Sant’Orsola-Malpighi HospitalUniversity of BolognaBolognaItaly

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