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Introduction

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Book cover Hepatitis A Virus in Food

Part of the book series: SpringerBriefs in Food, Health, and Nutrition ((BRIEFSFOOD))

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Abstract

Hepatitis A infection is the leading cause of viral hepatitis throughout the world. According to the World Health Organization, there are more than 1.4 million new cases of hepatitis A worldwide every year, and the cost of foodborne illness caused by hepatitis A in the USA is now estimated to be up to 36,000 US dollars, according to an analysis by Ohio State University (Scharff 2012).

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References

  • Abad FX, Pinto RM, Gajardo R, Bosch A (1997) Viruses in mussels: public health implications and depuration. J Food Prot 60:677–681

    Google Scholar 

  • Advisory Committee on the Microbiological Safety of Food (1998) Report on foodborne viral infections. HMSO, London

    Google Scholar 

  • Aragonès L, Bosch A, Pintó RM (2008) Hepatitis A virus mutant spectra under the selective pressure of monoclonal antibodies: codon usage constraints limit capsid variability. J Virol 82(4):1688–1700. doi:10.1128/jvi.01842-07

    Google Scholar 

  • Benabbes L, Ollivier J, Schaeffer J, Parnaudeau S, Rhaissi H, Nourlil J, Guyader F (2012) Norovirus and other human enteric viruses in Moroccan shellfish. Food Environ Virol:1–6. doi:10.1007/s12560-012-9095-8

  • Bosch A, Sánchez G, Le Guyader F, Vanaclocha H, Haugarreau L, Pinto RM (2001) Human enteric viruses in Coquina clams associated with a large hepatitis A outbreak. Water Sci Technol 43(12):61–65

    Google Scholar 

  • Bostock AD, Mepham P, Phillips S, Skidmore S, Hambling MH (1979) Hepatitis A infection associated with the consumption of mussels. J Infect 1(2):171–177. doi:10.1016/s0163-4453(79)80010-9

    Google Scholar 

  • Boxman ILA, te Loeke NAJM, Klunder K, Hägele G, Jansen CCC (2011) Surveillance study of hepatitis A virus RNA on fig and date samples. Appl Environ Microbiol. doi:10.1128/aem.06574-11

  • Calder L, Simmons G, Thornley C, Taylor P, Pritchard K, Greening G, Bishop J (2003) An outbreak of hepatitis A associated with consumption of raw blueberries. Epidemiol Infect 131(1):745–751

    Google Scholar 

  • CDC (2003) Hepatitis A outbreak associated with green onions at a restaurant–Monaca, Pennsylvania, 2003. MMWR Morb Mortal Wkly Rep 52(47):1155–1157

    Google Scholar 

  • Costafreda MI, Bosch A, Pinto RM (2006) Development, evaluation and standardization of a real-time TaqMan reverse transcription-PCR assay for the quantification of hepatitis A virus in clinical and shellfish samples. Appl Environ Microbiol 72:3846–3855

    Google Scholar 

  • Costa-Mattioli M, Monpoeho S, Schvoerer C, Besse B, Aleman MH, Billaudel S, Cristina J, Ferre V (2001) Genetic analysis of hepatitis A virus outbreak in France confirms the co-circulation of subgenotypes Ia, Ib and reveals a new genetic lineage. J Med Virol 65(2):233–240

    Google Scholar 

  • Costa-Mattioli M, Cristina J, Romero H, Perez-Bercof R, Casane D, Colina R, Garcia L, Vega I, Glikman G, Romanowsky V, Castello A, Nicand E, Gassin M, Billaudel S, Ferré V (2002a) Molecular evolution of hepatitis A virus: a new classification based on the complete VP1 protein. J Virol 76:9516–9525

    Google Scholar 

  • Dagan R, Leventhal A, Anis E, Slater P, Ashur Y, Shouval D (2005) Incidence of hepatitis a in israel following universal immunization of toddlers. JAMA 294(2):202–210. doi:10.1001/jama.294.2.202

    Google Scholar 

  • Dentinger CM, Bower WA, Nainan OV, Cotter SM, Myers G, Dubusky LM, Fowler S, Salehi ED, Bell BP (2001) An outbreak of hepatitis A associated with green onions. J Infect Dis 183(8):1273–1276

    Google Scholar 

  • Domínguez A, Oviedo M, Carmona G, Batalla J, Bruguera M, Salleras L, Plasència A (2008) Impact and effectiveness of a mass hepatitis A vaccination programme of preadolescents seven years after introduction. Vaccine 26(14):1737–1741, doi:http://dx.doi.org/10.1016/j.vaccine.2008.01.048

    Google Scholar 

  • Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (2005) Virus taxonomy: the eighth report of the International Committee on Taxonomy of Viruses. Elsevier Academic Press, Amsterdam

    Google Scholar 

  • Felix-Valenzuela L, Resendiz-Sandoval M, Burgara-Estrella A, Hernández J, Mata-Haro V (2012) Quantitative detection of hepatitis A, rotavirus and genogroup I norovirus by RT-qPCR in fresh produce from packinghouse facilities. J Food Saf 32(4):467–473

    Google Scholar 

  • Fiore AE (2004) Hepatitis A transmitted by food. Clin Infect Dis 38:705–715

    Google Scholar 

  • Franco E, Vitiello G (2003) Vaccination strategies against hepatitis A in southern Europe. Vaccine 21(7–8):696–697, doi:http://dx.doi.org/10.1016/S0264-410X(02)00582-0

    Google Scholar 

  • Frank C, Walter J, Muehlen M, Jansen A, van Treeck U, Hauri AM, Zoellner I, Rakha M, Hoehne M, Hamouda O, Schreier E, Stark K (2007) Major outbreak of hepatitis A associated with orange juice among tourists, Egypt, 2004. Emerg Infect Dis 13(1):156–158. doi:10.3201/eid1301.060487

    Google Scholar 

  • Furuta T, Akiyama M, Kato Y, Nishio O (2003) A food poisoning outbreak caused by purple Washington clam contaminated with norovirus (Norwalk-like virus) and hepatitis A virus. Kansenshogaku Zasshi 77:89–94

    Google Scholar 

  • Gallot C, Grout L, Roque-Afonso AM, Couturier E, Carrillo-Santisteve P, Pouey J, Letort MJ, Hoppe S, Capdepon P, Saint-Martin S, De Valk H, Vaillant V (2011) Hepatitis A associated with semidried tomatoes, France, 2010. Emerg Infect Dis 17(3):566–567. doi:10.3201/eid1703.101479

  • Goh KT, Chan L, Ding JL, Oon CJ (1984) An epidemic of cockles-associated hepatitis A in Singapore. Bull World Health Organ 62(6):893–897

    Google Scholar 

  • Halliday ML, Kang L-Y, Zhou T-K, Hu M-D, Pan Q-C, Fu T-Y, Huang Y-S, Hu S-L (1991) An epidemic of hepatitis A attributable to the ingestion of raw clams in Shanghai, China. J Infect Dis 164(5):852–859. doi:10.2307/30111993

    Google Scholar 

  • Hazards EPoB (2011) Scientific Opinion on an update on the present knowledge on the occurrence and control of foodborne viruses. EFSA J 9:2190. doi:10.2903/j.efsa.2011.2190

  • Hutin YJ, Pool V, Cramer EH, Nainan OV, Weth J, Williams IT, Goldstein ST, Gensheimer KF, Bell BP, Shapiro CN, Alter MJ, Margolis HS (1999) A multistate, foodborne outbreak of hepatitis A. N Engl J Med 340(8):595–602

    Google Scholar 

  • Lemon SM, Binn LN (1983) Antigenic relatedness of two strains of hepatitis A virus determined by cross-neutralization. Infect Immun 42(1):418–420

    Google Scholar 

  • Lu L, Ching KZ, De Paula VS, Nakano T, Siegl G, Weitz M, Robertson BH (2004) Characterization of the complete genomic sequence of genotype II hepatitis A virus (CF53/Berne isolate). J Gen Virol 85:2943–2952

    Google Scholar 

  • Mackowiak PA, Caraway CT, Portnoy BL (1976) Oyster-associated hepatitis: lessons from the louisiana experience. Am J Epidemiol 103(2):181–191

    Google Scholar 

  • Milazzo L, Vale S (2005) Hepatitis A associated with green onions. New Engl J Med 353(21):2300–2301

    Google Scholar 

  • Nainan OV, Xia G, Vaughan G, Margolis HS (2006) Diagnosis of hepatitis A virus infection: a molecular approach. Clin Microbiol Rev 19(1):63–79

    Google Scholar 

  • Niu MT, Polish LB, Robertson BH, Khanna BK, Woodruff BA, Shapiro CN, Miller MA, Smith JD, Gedrose JK, Alter MJ, Margolis HS (1992) Multistate outbreak of hepatitis A associated with frozen strawberries. J Infect Dis 166(3):518–524

    Google Scholar 

  • Noble RC, Kane MA, Reeves SA, Roeckel I (1984) Posttransfusion hepatitis A in a neonatal intensive care unit. JAMA 252(19):2711–2725

    Google Scholar 

  • Pérez-Sautu U, Costafreda MI, Lite J, Sala R, Barrabeig I, Bosch A, Pintó RM (2011) Molecular epidemiology of hepatitis A virus infections in Catalonia, Spain, 2005–2009: circulation of newly emerging strains. J Clin Virol 52(2):98–102. doi:10.1016/j.jcv.2011.06.011

    Google Scholar 

  • Petrignani M, Harms M, Verhoef L, van Hunen R, Swaan C, van Steenbergen J, Boxman I, Sala RPI, Ober HJ, Vennema H, Koopmans M, van Pelt W (2010) Update: a food-borne outbreak of hepatitis a in the Netherlands related to semi-dried tomatoes in oil, January-February 2010. Eurosurveillance 15(20)

    Google Scholar 

  • Pinto RM, Costafreda MI, Bosch A (2009) Risk assessment in shellfish-borne outbreaks of hepatitis A. Appl Environ Microbiol 75(23):7350–7355

    Google Scholar 

  • Prato R, Martinelli D, Tafuri S, Barbuti G, Quarto M, Germinario CA, Chironna M (in press) Safety of shellfish and epidemiological pattern of enterically transmitted diseases in Italy. Int J Food Microbiol. doi:http://dx.doi.org/10.1016/j.ijfoodmicro.2012.12.025

  • Ramsay CN, Upton PA (1989) Hepatitis A and frozen raspberries. Lancet 1(8628):43–44

    Google Scholar 

  • Reid TM, Robinson HG (1987) Frozen raspberries and hepatitis A. Epidemiol Infect 98(1):109–112

    Google Scholar 

  • Robertson BH, Jansen RW, Khanna B, Tosuka A, Nainan OV, Siegl G, Widell A, Margolis HS, Isomura S, Ito K, Ishizu T, Moritsugu Y, Lemon SM (1992) Genetic relatedness of hepatitis A virus strains recovered from different geographical regions. J Gen Virol 73:1365–1377

    Google Scholar 

  • Robesyn E, De Schrijver K, Wollants E, Top G, Verbeeck J, Van Ranst M (2009) An outbreak of hepatitis A associated with the consumption of raw beef. J Clin Virol 44(3):207–210. doi:10.1016/j.jcv.2008.12.012

    Google Scholar 

  • Rosenblum LS, Mirkin IR, Allen DT, Safford S, Hadler SC (1990) A multifocal outbreak of hepatitis A traced to commercially distributed lettuce. Am J Public Health 80(9):1075–1079

    Google Scholar 

  • Sánchez G, Pinto RM, Vanaclocha H, Bosch A (2002) Molecular characterization of hepatitis a virus isolates from a transcontinental shellfish-borne outbreak. J Clin Microbiol 40:4148–4155

    Google Scholar 

  • Sánchez G, Bosch A, Gomez-Mariano G, Domingo E, Pinto RM (2003a) Evidence for quasispecies distributions in the human hepatitis A virus genome. Virology 315(1):34–42

    Google Scholar 

  • Sánchez G, Bosch A, Pinto RM (2003b) Genome variability and capsid structural constraints of hepatitis a virus. J Virol 77(1):452–459

    Google Scholar 

  • Scharff RL (2012) Economic burden from health losses due to foodborne illness in the United States. J Food Prot 75(1):123–131. doi:10.4315/0362-028x.jfp-11-058

  • Schmid D, Fretz R, Buchner G, König C, Perner H, Sollak R, Tratter A, Hell M, Maass M, Strasser M, Allerberger F (2009) Foodborne outbreak of hepatitis A, November 2007–January 2008, Austria. Eur J Clin Microbiol Infect Dis 28(4):385–391. doi:10.1007/s10096-008-0633-0

    Google Scholar 

  • Shieh YC, Khudyakov YE, Xia G, Ganova-Raeva LM, Khambaty FM, Woods JW, Veazey JE, Motes ML, Glatzer MB, Bialek SR, Fiore AE (2007) Molecular confirmation of oysters as the vector for hepatitis A in a 2005 multistate outbreak. J Food Prot 70(1):145–150

    Google Scholar 

  • Van Boxstael S, Habib I, Jacxsens L, De Vocht M, Baert L, Van De Perre E, Rajkovic A, Lopez-Galvez F, Sampers I, Spanoghe P, De Meulenaer B, Uyttendaele M (2013) Food safety issues in fresh produce: bacterial pathogens, viruses and pesticide residues indicated as major concerns by stakeholders in the fresh produce chain. Food Control 32:190–197

    Google Scholar 

  • Wang MJ, Moran GJ (2004) Hepatitis A outbreak associated with green onions at a restaurant – Monaca, Pennsylvania, 2003. Ann Emerg Med 43(5):660–663

    Google Scholar 

  • Wasley A, Samandari T, Bell BP (2005) Incidence of hepatitis a in the united states in the era of vaccination. JAMA 294(2):194–201. doi:10.1001/jama.294.2.194

    Google Scholar 

  • Weltman AC, Bennett NM, Ackman DA, Misage JH, Campana JJ, Fine LS, Doniger AS, Balzano GJ, Birkhead GS (1996) An outbreak of hepatitis A associated with a bakery, New York, 1994: the 1968 ‘West branch, Michigan’ outbreak repeated. Epidemiol Infect 117(2):333–341

    Google Scholar 

  • Wheeler C, Vogt TM, Armstrong GL, Vaughan G, Weltman A, Nainan OV, Dato V, Xia G, Waller K, Amon J, Lee TM, Highbaugh-Battle A, Hembree C, Evenson S, Ruta MA, Williams IT, Fiore AE, Bell BP (2005) An outbreak of hepatitis A associated with green onions. N Engl J Med 353(9):890–897

    Google Scholar 

  • Yezli S, Otter J (2011) Minimum infective dose of the major human respiratory and enteric viruses transmitted through food and the environment. Food Environ Virol 3(1):1–30. doi:10.1007/s12560-011-9056-7

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  1. IATA-CSIC, Novel Materials, Nanotechnology, Institute of Agrochemistry and Food Technology, Valencia, Spain

    Gloria Sánchez

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  1. Gloria Sánchez
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© 2013 Gloria Sanchez

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Sánchez, G. (2013). Introduction. In: Hepatitis A Virus in Food. SpringerBriefs in Food, Health, and Nutrition. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7104-2_1

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