Myoepithelial Tumors

  • Cyril Fisher
Part of the Atlas of Anatomic Pathology book series (AAP)


Soft tissue neoplasms that display myoepithelial differentiation have a range of appearances similar to those arising in the salivary glands, with fascicular or trabecular architecture and epithelioid, clear cell, plasmacytoid, or spindled cytomorphology. Mixed tumors are defined by additionally having ductules or chondroid stroma. This category now includes tumors formerly termed parachordoma, although there are subtle differences between the two entities, and possibly some occurrences of ectomesenchymal chondromyxoid tumor, a very rare lesion of the anterior tongue. Ectopic hamartomatous thymoma (see Chap. 15) also has some features suggestive of myoepithelial differentiation.


Public Health Soft Tissue Tissue Neoplasm Salivary Gland Clear Cell 
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Suggested Reading

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  6. Mentzel T, Requena L, Kaddu S, Soares de Aleida LM, Sangueza OP, Kutzner H. Cutaneous myoepithelial neoplasms: clinicopathologic and immunohistochemical study of 20 cases suggesting a continuous spectrum ranging from benign mixed tumor of the skin to cutaneous myoepithelioma and myoepithelial carcinoma. J Cutan Pathol. 2003;30:294–302.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Cyril Fisher
    • 1
  1. 1.Department of HistopathologyThe Royal Marsden HospitalLondonUK

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