It now is recognized that a hemangiopericytic vascular pattern characterized by irregularly shaped, dilated, thin-walled blood vessels is a nonspecific finding in a wide range of neoplasms. Most tumors previously diagnosed as hemangiopericytomas are categorized as specific entities, such as synovial sarcoma, and many CD34-positive examples are interpreted as solitary fibrous tumors.
Pericytes form a single layer of cells around some capillary vessels and can manifest glomus-like or smooth muscle–like (myopericytomatous) features. True tumors of pericytes are uncommon and include myopericytomas and glomangiopericytomas. There is overlap with myofibroma. In such cases, the hemangiopericytomatous vascular pattern remains an adventitious phenomenon rather than being a specific lineage-related feature.
Public Health Smooth Muscle Blood Vessel Single Layer Synovial Sarcoma
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.
Dictor M, Elner A, Andersson T, Ferno M. Myofibromatosis-like hemangiopericytoma metastasizing as differentiated vascular smooth muscle and myosarcoma. Myopericytes as a subset of “myofibroblasts”. Am J Surg Pathol. 1992;16:1239–47.PubMedCrossRefGoogle Scholar
Folpe AL, Fanburg-Smith JC, Miettinen M, Weiss SW. Atypical and malignant glomus tumors: analysis of 52 cases, with a proposal for the reclassification of glomus tumors. Am J Surg Pathol. 2001;25:1–12.PubMedCrossRefGoogle Scholar
Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998;22:513–25.PubMedCrossRefGoogle Scholar
McMenamin ME, Fletcher CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology. 2002;41:450–60.PubMedCrossRefGoogle Scholar
Mentzel T, Dei Tos AP, Sapi Z, Kutzner H. Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol. 2006;30:104–13.PubMedCrossRefGoogle Scholar
Miettinen M, Paal E, Lasota J, Sobin LH. Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 2002;26:301–11.PubMedCrossRefGoogle Scholar
Nappi O, Ritter JH, Pettinato G, Wick MR. Hemangiopericytoma: histopathological pattern or clinicopathologic entity? Semin Diagn Pathol. 1995;12:221–32.PubMedGoogle Scholar
Thompson LD, Miettinen M, Wenig BM. Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol. 2003;27:737–49.PubMedCrossRefGoogle Scholar