Tumors of Adipose Tissue
Tumors of adipose tissue are the most frequently encountered benign or malignant soft tissue tumors. Lipomas may occur at almost any site and represent the most common benign soft tissue neoplasm. Liposarcoma has a high incidence among malignant soft tissue tumors, but the term includes several distinct lipogenic tumor types that vary clinically, histogenetically, and genetically. These include tumors with increased copy numbers (gene amplification), specific translocations, or complex karyotypes, but there are no significant predisposing factors.
Lipoblasts are a distinctive feature of some liposarcomas, but their presence is not necessary for the microscopic diagnosis of well-differentiated liposarcomas or myxoid liposarcomas.
KeywordsComplex Karyotype Increase Copy Number Myxoid Liposarcomas Deep Soft Tissue Lipomatous Tumor
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