Abstract
The purpose of this chapter is to describe clinical strategies that parents and professionals can use to improve treatments provided to students on the autism spectrum. The focus of the chapter is to explain the complexity of treatments that may be effective with Asperger students and others on the spectrum.
The content in this chapter should not be considered a substitute for medical or other professional advice. The publisher and the authors intend to offer accurate information that reflects current knowledge of the subject covered. The publisher and authors make no representations as to the accuracy or efficacy of specific medications or dosages presented in this chapter.
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References
Black, J. L., III, O’Kane, D. J., & Mrazek, D. A. (2007). The impact of CYP allelic variation on antidepressant metabolism: A review. Expert Opinion on Drug Metabolism & Toxicology, 3(1), 21–31.
Kim, S., Leventhal, B. L., Koh, Y. J., Fombonne, E., Laska, E., Lim, E. C., et al. (2011). Prevalence of autism spectrum disorders in a total population sample. The American Journal of Psychiatry, 168(9), A54.
Klin, A., Volkmar, F. R., & Sparrow, S. S. (2000). Asperger syndrome psychopharmacological treatment of higher functioning pervasive developmental disorders (p. 219). New York: Guilford Press.
Malhotra, A. K., Goldman, D., & Mazzanti, C. (1998). A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics. Molecular Psychiatry, 3, 328–332.
Malhotra, A. K., Murphy, G. M., & Kennedy, J. L. (2004). Pharmacogenetics of psychotropic drug response. The American Journal of Psychiatry, 161(5), 780–796.
Mattila, M. L., Hurtig, T., Haapsamo, H., Jussila, K., Kuusikko-Gauffin, S., Kielinen, M., et al. (2010). Comorbid psychiatric disorders associated with Asperger syndrome high-functioning autism: A community- and clinic-based study. Journal of Autism and Developmental Disorders, 40(9), 1080–1093.
Mefford, H., & Eichler, E. E. (2009). Duplication hotspots, rare genomic disorders, and common disease. Genetics and Development, 19(3), 196–204.
Mesibov, G. B., Shea, V., & Adams, L. W. (2001). Understanding asperger syndrome and high functioning autism. New York: Kluwer Academic/Plenum.
Mrazek, D. A. (2010). Psychiatric pharmacogenomics (pp. 39–53). New York: Oxford University Press.
National Human Genome Research Institute. (2012). Frequently asked questions about genetic testing. Retrieved October 13, 2011, from http://www.genome.gov/1951656710/13/11.
Ruaño, G., Villagra, D., Rahim, U.-S., Windemuth, A., Kocherla, M., & Bower, B. (2008). Increased carrier prevalence of deficient CYP2C9, CYP2C19 and CYP2D6 alleles in depressed patients referred to a tertiary psychiatric hospital. Personalized Medicine, 5, 579–587.
Ruaño, G., Villagra, D., Szarek, B., Windemuth, A., Kocherla, M., Gorowski, K. (2011). Physiogenomic analysis of CYP450 drug metabolism correlates dyslipidemia with pharmacogenetic functional status in psychiatric patients. Biomarkers in Medicine, 5(4), 439–449.
Salyakina, D., Ma, D. Q., Jaworski, J. M., Konidari, I., Whitehead, P. L., Henson, R., et al. (2010). Variants in several genomic regions associated with asperger disorder. Autism Research, 3(6), 303–310.
Singer, E. (2009a). Interpreting the genome. MIT Technology Review, 112(1), 48–53.
Singer, E. (March/April, 2009b). A hole in the genome. Technology Review. Retrieved September 19, 2012, from http://www.technologyreview.com/review/412209/a-hole-in-the-genome.
Shute, N., & Christie, B. (2010). Desperate for an autism cure. Scientific American, 303(6), 80–85.
Smith, B. L. (2012). Inappropriate prescribing. Monitoring on Psychology, 43(6), 38–40.
The Learning Clinic. (2011). Preliminary findings for TLC applied research: Results of pharmacology-genotyping among TLC students. Retrieved September 19, 2012, from http://www.thelearningclinic.org.
Villagra, D., Goethe, J., Schwartz, H. I., Szarek, B., Kocherla, M., Gorowski, K., et al. (2011) Novel drug metabolism indices for pharmacogenetic functional status based on combinatory genotyping of CYP2C9, CYP2C19 and CYP2D6 genes. Biomarkers in Medicine, 5(4), 427–438.
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DuCharme, R.W., McGrady, K.A., Patel, J.C., Ruaño, G. (2013). Comprehensive Education-Based Mental Health Services for Students Diagnosed on the Autism Spectrum. In: DuCharme, R., Gullotta, T. (eds) Asperger Syndrome. Issues in Children's and Families' Lives. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-7016-8_7
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DOI: https://doi.org/10.1007/978-1-4614-7016-8_7
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