Abstract
Azoospermia refers to the clinical finding that sperm are not detectable in the ejaculate after centrifugation and microscopic analysis of two semen samples. This condition affects approximately 1 % of the general male population and 15 % of subfertile men. Azoospermia is generally indicative of either complete bilateral obstruction of the male excurrent ductal system (obstructive azoospermia) or severely impaired sperm production (nonobstructive azoospermia). Fertility is only possible in affected men through medical or surgical intervention. The goals of the diagnostic evaluation are to identify underlying etiologies that are of medical or prognostic significance, to identify genetic abnormalities that may affect the patient’s offspring, and to guide the selection of medical or surgical therapy. The differential diagnosis of azoospermia is listed in Table 3.1.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Carpi A, Sabanegh E, Mechanick J. Controversies in the management of non-obstructive azoospermia. Fertil Steril. 2009;91(4):963–70.
Goldstein M, Tanrikut C. Microsurgical management of male infertility. Nat Clin Pract Urol. 2006;3(7):381–9.
Jarow JP, Espeland MA, Lipshultz LI. Evaluation of the azoospermic patient. J Urol. 1989;142(1):62–5.
Male Infertility Best Practice Policy Committee of the American Urological Association, and Practice Committee of the American Society for Reproductive Medicine. Report on evaluation of the azoospermic male. Fertil Steril. 2006;86(5 Suppl 1):S210–5.
Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Male Reproduction and Urology. The management of infertility due to obstructive azoospermia. Fertil Steril. 2008;90(5 Suppl):S121–4.
Schlegel PN. Non-obstructive azoospermia: a revolutionary surgical approach and results. Semin Reprod Med. 2009;27(2):165–70.
Stahl PJ, Schlegel PN. Genetic evaluation of the azoospermic or severely oligozoospermic male. Curr Opin Obstet Gynecol. 2012;24(4):221–8.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Mulhall, J.P., Stahl, P.J., Stember, D.S. (2014). Azoospermia. In: Clinical Care Pathways in Andrology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6693-2_3
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6693-2_3
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-6692-5
Online ISBN: 978-1-4614-6693-2
eBook Packages: MedicineMedicine (R0)