Abstract
Acquired diffuse hyperpigmentation in children secondary to metabolic disorders can be divided into nutritional diseases, endocrinological disorders, and metabolic causes. Although pigmentation is categorized as diffuse, it is often accentuated in some areas. Adequate approach of diffuse hyperpigmentation may lead to the early diagnosis of a specific disease. The initial and most prominent sign can be in the skin and thus the dermatologist is the first physician consulted.
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Orozco-Covarrubias, L., Sáez-de-Ocariz, M. (2015). Metabolic Hyperpigmentation: Carotenemia, Pernicious Anemia, Acromegaly, Addison’s Disease, Diabetes mellitus, and Hemochromatosis. In: Silverberg, N., Durán-McKinster, C., Tay, YK. (eds) Pediatric Skin of Color. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6654-3_13
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