Cirrhosis: Gastrointestinal Features



Cirrhosis is the end stage of chronic liver disease characterized by the presence of fibrosis and scar tissue. This stage of liver disease is associated with multiple complications and causes poor quality of life, increased risk of infection, and has a poor prognosis. Although the disease is centered in the liver, it has myriad effects in other organ systems. Cirrhosis has a 10-year mortality of 34–66 %. The wide range is due to differences in the various etiologies of disease.

Gastrointestinal (GI) symptoms include:

Increasing abdominal girth from ascites

Upper GI bleeding or rectal bleeding

Clinical signs and findings include:

Development of portal hypertension


Obesity Hepatitis Lactulose Hemochromatosis 


  1. 1.
    Pinzani M, Rosselli M. Liver cirrhosis. Best Pract Res Clin Gastroenterol. 2011;25:281–90.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Internal MedicineUniversity of Connecticut Health CenterFarmingtonUSA
  2. 2.Eastern Connecticut Medical ProfessionalsManchesterUSA
  3. 3.Department of PathologyUniversity of Connecticut Health CenterFarmingtonUSA

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