Behçet’s Syndrome: Gastrointestinal Features



Behçet’s syndrome causes gastrointestinal (GI) manifestations in 3–26 % of patients and is more common in patients from Asia than from the Middle East or the Mediterranean region.

GI features include:

Anorexia, diarrhea, abdominal pain, bloody stools, abdominal masses, small bowel obstructive symptoms

More severe: intestinal stenosis, perforation, persistent bleeding

Clinical signs and findings in Behçet’s Syndrome include:

Punched-out ulcers are the most common GI finding, found most often in the ileum, then the cecum, then the rest of colon ileocecal ulcers have a tendency to perforate

Hallmark is recurrent aphthous ulcers; also skin findings of genital ulcers, papulopustular acne-like rash, nodular rashes (erythema nodosum-like and superficial thrombosis)


Genital Ulcer Bloody Stool Persistent Bleeding Intestinal Stenosis Skin Finding 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Yale Department of Internal MedicineYale New Haven HospitalNew HavenUSA

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