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Behçet’s Syndrome: Gastrointestinal Features

Chapter

Abstract

Behçet’s syndrome causes gastrointestinal (GI) manifestations in 3–26 % of patients and is more common in patients from Asia than from the Middle East or the Mediterranean region.

GI features include:

Anorexia, diarrhea, abdominal pain, bloody stools, abdominal masses, small bowel obstructive symptoms

More severe: intestinal stenosis, perforation, persistent bleeding

Clinical signs and findings in Behçet’s Syndrome include:

Punched-out ulcers are the most common GI finding, found most often in the ileum, then the cecum, then the rest of colon ileocecal ulcers have a tendency to perforate

Hallmark is recurrent aphthous ulcers; also skin findings of genital ulcers, papulopustular acne-like rash, nodular rashes (erythema nodosum-like and superficial thrombosis)

Keywords

Genital Ulcer Bloody Stool Persistent Bleeding Intestinal Stenosis Skin Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Mendes D, Correia M, Barbedo M, et al. Behçets disease: a contemporary review. J Autoimmunity. 2009;32:178–88.CrossRefGoogle Scholar
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    Hassard PV, Binder SW, Nelson V, Vasiliauskas EA. Anti-tumor necrosis factor monoclonal antibody therapy for gastrointestinal Behçet’s disease: a case report. Gastroenterology. 2001;120:995–9.PubMedCrossRefGoogle Scholar
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    Kram MT, May LD, Goodman S, et al. Behçet’s ileocolitis: successful treatment with tumor necrosis factor-alpha antibody (infliximab) therapy: report of a case. Dis Colon Rectum. 2003;46:118–21.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Yale Department of Internal MedicineYale New Haven HospitalNew HavenUSA

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