Abstract
Cowden’s syndrome is a rare hereditary condition affecting about one per 200,000 people in the United States In terms of gastrointestinal (GI) symptoms, most individuals are asymptomatic and pathology is found incidentally.
When present, the most common GI signs and findings are:
Polyps, predominantly in the colon, but also in the stomach, small bowel, and esophagus
Forty percent of individuals have GI findings, but this is likely an underestimate as asymptomatic individuals rarely get a full work up. Some studies have estimated up to 85 % of individuals have GI involvement
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Zakko, L. (2013). Cowden’s Syndrome: Gastrointestinal Features. In: Wu, G., Selsky, N., Grant-Kels, J. (eds) Atlas of Dermatological Manifestations of Gastrointestinal Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6191-3_37
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DOI: https://doi.org/10.1007/978-1-4614-6191-3_37
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