Plummer-Vinson Syndrome: Gastrointestinal Features



Plummer-Vinson syndrome consists of the triad of dysphagia, esophagitis, and iron deficiency anemia. The disease is more common in women than in men and often occurs in the menopausal period after age 50. The gastrointestinal symptoms associated with this disease are:

Intermittent dysphagia to solids that progresses over years

Occasionally weight loss

The classic clinical signs and findings include:

Triad of dysphagia, iron deficiency anemia, upper esophageal webs

Signs and symptoms of iron deficiency often predominate

Esophageal webs are smooth, thin, and gray with a central lumen. Usually extend from the anterior wall laterally and are found in the proximal part of the esophagus


Anemia Barium Triad Esophagitis Scleroderma 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Yale Department of Internal MedicineYale New Haven HospitalNew HavenUSA

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