Dermatomyositis: Gastrointestinal Features

  • Laura Nieves


Dermatomyositis is a connective tissue disease associated with inflammation of the muscles and skin. The exact cause remains unknown. There is evidence that the disease is autoimmune in origin but may also have components of viral infection and can be drug-induced, as well. Although the presentation is mainly with skin rash and proximal muscle weakness, the disease can affect multiple organs.

Gastrointestinal (GI) symptoms of dermatomyositis include:

Dysphagia, dysmotility, megaesophagus

Nasal regurgitation and nasal speech



Ulceration, perforation, or hemorrhage anywhere along GI tract (rare)

Pancreatitis, cholestasis, and hepatomegaly have been reported in juvenile diabetes mellitus


Creatine Kinase Connective Tissue Disease Mycophenolate Mofetil Inclusion Body Myositis Polymyalgia Rheumatica 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Internal MedicineUniversity of Connecticut Health CenterFarmingtonUSA

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