Dermatomyositis is a connective tissue disease associated with inflammation of the muscles and skin. The exact cause remains unknown. There is evidence that the disease is autoimmune in origin but may also have components of viral infection and can be drug-induced, as well. Although the presentation is mainly with skin rash and proximal muscle weakness, the disease can affect multiple organs.
Gastrointestinal (GI) symptoms of dermatomyositis include:
Dysphagia, dysmotility, megaesophagus
Nasal regurgitation and nasal speech
Ulceration, perforation, or hemorrhage anywhere along GI tract (rare)
Pancreatitis, cholestasis, and hepatomegaly have been reported in juvenile diabetes mellitus