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Conductive Polymer-Based Materials for Medical Electroanalytic Applications

  • Vessela Tsakova
Chapter
Part of the Modern Aspects of Electrochemistry book series (MAOE, volume 56)

Abstract

Since the discovery of high electrical conductivity in doped polyacetylene in 1977 [1], the investigations in the field of conducting polymers (CPs) have expanded rapidly in number, scope of research, and importance. The 2000 Nobel Prize in Chemistry was awarded to A. J. Heeger, A. McDiarmid, and H. Shirakawa for the discovery and development of electrically conductive polymers. The choice of the Nobel Committee was motivated by the important scientific position that the field has achieved and the consequences in terms of practical applications and of interdisciplinary development between chemistry and physics [2]. In the last decade the field of CPs and various CP-based materials has advanced further into new areas of research and technological developments. One of these intensively progressing areas is the involvement of CP-based materials in electrocatalytical applications, with a strong emphasis set on chemical and biochemical sensing. The electroanalytical response of CPs and CP-based composites was studied for a great number of compounds that are involved in the human metabolism, present medications, or harmful chemicals for humans. The large amount of publications on medical electroanalytical applications of CP-based materials are scattered over a number of specialized journals with main scopes in electroanalytical and analytical chemistry, sensing and biosensing, polymer science, medical studies, etc. Due to the highly spread and abundant literature it is nowadays difficult to get a general idea in this specific field of research. The present chapter attempts to outline the state of the art and hopefully to provoke further effort in this challenging scientific area with practical importance for medical diagnostics and medical treatments.

Keywords

Ascorbic Acid Uric Acid Redox Mediator NADH Oxidation PANI Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

AA

Ascorbic acid

ABSA

Aminobenzenesulfonic acid

CA

Chronoamperometry

CP

Conducting polymers

CPE

Carbon paste electrode

CNT

Carbon nanotubes

CV

Cyclic voltammetry

DA

Dopamine

DPV

Differential pulse voltammetry

EPI

Epinephrine

FIA

Flow injection analysis

LbL

Layer-by-layer

LOD

Limit of detection

MIP

Molecularly imprented polymer

MSE

Mercury sulfate electrode

MWCNT

Multiwalled carbon nanotubes

NAD+

Nicotinamide adenine dinucleotide

NOREPI

Norepinephrine

NPs

Nanoparticles

P3MT

Poly(3-methylthiophene)

PAA

Polyacrilic acid

PAMPSA

Poly(2-acryalamido-2-methyl-1-propane-sulfonic acid)

PANI

Polyaniline

PEDOT

Poly(3,4-ethylenedioxythiophene)

POMA

Poly(o-methoxyaniline)

PPY

Polypyrrole

PSS

Polysterenesulfonate

PTHI

Polythiophene

PVS

Polyvinylsulfonate

RDE

Rotating disc electrode

SCE

Standard calomel electrode

SDS

Sodium dodecylsulfate

SHE

Standard hydrogen electrode

SWCNT

Single-walled carbon nanotubes

SWV

Square wave voltammetry

UA

Uric acid

Notes

Acknowledgments

Financial support of project DTK 02/25 with National Science Fund of Bulgaria is gratefully acknowledged.

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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Institute of Physical Chemistry, Bulgarian Academy of SciencesSofiaBulgaria

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