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Taurine 8 pp 347–355Cite as

Taurine Enhances the Sexual Response and Mating Ability in Aged Male Rats

Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 776)


It has been demonstrated that taurine is abundant in male reproductive organs, and can be biosynthesized by testis, but the taurine concentration will reduce with aging. The levels of serum LH, T, NOS, and NO were found to be obviously increased by taurine supplementation in aged rats in our previous study. In addition, aging will result in a significant decline in sexual response and function, which may be attributed to the androgen deficiency. Furthermore, NO has been proposed as a crucial mediator of penile erection. That makes us hypothesize that there is potential relationship between taurine decline and erection dysfunction in aged males. So the primary aim of the present study was to investigate the effect of taurine on male sexuality in rats. Taurine was offered in water to male aged (20 months old) rats for 110 days. The effects of taurine on the sexual response, mating ability, levels of serum reproductive hormones, and penile NOS and NO levels were investigated. The results showed that taurine can significantly reduce the EL and ML; obviously increase the ERF, MF, IF, and EJF; stimulate the secretion of GnRH, LH, and T; and elevate penis NOS and NO level in aged rats. The results indicated that taurine can enhance the sexual response and mating ability in aged male rats by increasing the level of testosterone and NO, but the exact mechanism of which needs to be further investigated.


  • Nitric Oxide
  • Luteinizing Hormone
  • Sexual Response
  • Penile Erection
  • Taurine Supplement

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  • DOI: 10.1007/978-1-4614-6093-0_32
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Fig. 32.1
Fig. 32.2
Fig. 32.3
Fig. 32.4
Fig. 32.5
Fig. 32.6



Luteinizing hormone




Nitric oxide synthase


Nitric oxide


Control group


Taurine group


β-Alanine group


Erection latency


Erection frequency


Mount latency


Mount frequency


Intromission frequency


Ejaculation frequency


Gonadotropin-releasing hormone


Follicle-stimulating hormone




Luteinizing hormone


Total protein


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This work was supported by the National Natural Science Foundation of China (Grant No. 31001042), the Doctor Initial Foundation of Liaoning Province (Grant No. 20081065), and the Program for Shenyang Agricultural University Excellent Talents.

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Correspondence to Jianmin Hu .

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Yang, J., Lin, S., Feng, Y., Wu, G., Hu, J. (2013). Taurine Enhances the Sexual Response and Mating Ability in Aged Male Rats. In: El Idrissi, A., L'Amoreaux, W. (eds) Taurine 8. Advances in Experimental Medicine and Biology, vol 776. Springer, New York, NY.

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