Taurine 8 pp 179-187 | Cite as

Additional Effects of Taurine on the Benefits of BCAA Intake for the Delayed-Onset Muscle Soreness and Muscle Damage Induced by High-Intensity Eccentric Exercise

  • Song-Gyu Ra
  • Teruo Miyazaki
  • Keisuke Ishikura
  • Hisashi Nagayama
  • Takafumi Suzuki
  • Seiji Maeda
  • Masaharu Ito
  • Yasushi Matsuzaki
  • Hajime Ohmori
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 776)

Abstract

Taurine (TAU) has a lot of the biological, physiological, and pharmocological functions including anti-inflammatory and anti-oxidative stress. Although previous studies have appreciated the effectiveness of branched-chain amino acids (BCAA) on the delayed-onset muscle soreness (DOMS), consistent finding has not still convinced. The aim of this study was to examine the additional effect of TAU with BCAA on the DOMS and muscle damages after eccentric exercise. Thirty-six untrained male volunteers were equally divided into four groups, and ingested a combination with 2.0 g TAU (or placebo) and 3.2 g BCAA (or placebo), thrice a day, 2 weeks prior to and 4 days after elbow flexion eccentric exercise. Following the period after eccentric exercise, the physiological and blood biochemical markers for DOMS and muscle damage showed improvement in the combination of TAU and BCAA supplementation rather than in the single or placebo supplementations. In conclusion, additional supplement of TAU with BCAA would be a useful way to attenuate DOMS and muscle damages induced by high-intensity exercise.

References

  1. Fridén J, Kjörell U, Thornell LE (1984) Delayed muscle soreness and cytoskeletal alterations: an immunocytological study in man. Int J Sports Med 5:15–18PubMedCrossRefGoogle Scholar
  2. Ishikura K, Miyakawa S, Yatabe Y, Takekoshi K, Ohmori H (2008) Effect of taurine supplementation on blood glucose concentration during prolonged exercise. Jpn J Phys Fit Sport 57:475–484CrossRefGoogle Scholar
  3. Ishikura K, Miyazaki T, Ra S-G, Endo S, Nakamura Y, Matsuzaka T, Miyakawa S, Ohmori H (2011) Effect of taurine supplementation on the alterations in amino acid content in skeletal muscle with exercise in rat. J Sports Sci Med 10:306–314Google Scholar
  4. Jackman SR, Witard OC, Jeukendrup AE, Tipton KD (2010) Branched-chain amino acid ingestion can ameliorate soreness from eccentric exercise. Med Sci Sports Exerc 42:962–970PubMedCrossRefGoogle Scholar
  5. Jacobsen JG, Smith LH (1968) Biochemistry and physiology of taurine and taurine derivatives. Physiol Rev 48:424–511PubMedGoogle Scholar
  6. Lavender A, Nosaka K (2008) Changes in markers of muscle damage of middle-aged and young men following eccentric exercise of the elbow flexors. J Sci Med Sport 11:124–131PubMedCrossRefGoogle Scholar
  7. Miyazaki T, Matsuzaki Y, Ikegami T, Miyakawa S, Doy M, Tanaka N, Bouscarel B (2004a) Optimal and effective oral dose of taurine to prolong exercise performance in rat. Amino Acids 27:291–298PubMedCrossRefGoogle Scholar
  8. Miyazaki T, Matsuzaki Y, Ikegami T, Miyakawa S, Doy M, Tanaka N, Bouscarel B (2004b) The harmful effect of exercise on reducing taurine concentration in the tissues of rats treated with CCl4 administration. J Gastroenterol 39:557–562PubMedGoogle Scholar
  9. Miyazaki T, Karube M, Matsuzaki Y, Ikegami T, Doy M, Tanaka N, Bouscarel B (2005) Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis. J Hepatol 43:117–125PubMedCrossRefGoogle Scholar
  10. Nosaka K, Sacco P, Mawatari K (2006) Effects of amino acid supplementation on muscle soreness and damage. Int J Sport Nutr Exerc Metab 16:620–635PubMedGoogle Scholar
  11. Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N, Kobayashi H, Mawatari K (2006) Nutraceutical effects of branched-chain amino acids on skeletal muscle. J Nutr 136:529S–532SPubMedGoogle Scholar
  12. Shimomura Y, Inaguma A, Watanabe S, Yamamoto Y, Muramatsu Y, Bajotto G, Sato J, Shimomura N, Kobayashi H, Mawatari K (2010) Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness. Int J Sport Nutr Exerc Metab 20:236–244PubMedGoogle Scholar
  13. Silva LA, Silveira PC, Ronsani MM, Souza PS, Scheffer D, Vieira LC, Benetti M, De Souza CT, Pinho RA (2011) Taurine supplementation decreases oxidative stress in skeletal muscle after eccentric exercise. Cell Biochem Funct 29:43–49PubMedCrossRefGoogle Scholar
  14. White JP, Wilson JM, Austin KG, Greer BK, St John N, Panton LB (2008) Effect of carbohydrate-protein supplement timing on acute exercise-induced muscle damage. J Int Soc Sports Nutr 5:5PubMedCrossRefGoogle Scholar
  15. Yatabe Y, Miyakawa S, Miyazaki T, Matsuzaki Y, Ochiai N (2003) Effects of taurine administration in rat skeletal muscles on exercise. J Orthop Sci 8:415–419PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Song-Gyu Ra
    • 1
  • Teruo Miyazaki
    • 2
  • Keisuke Ishikura
    • 3
  • Hisashi Nagayama
    • 4
  • Takafumi Suzuki
    • 1
  • Seiji Maeda
    • 1
  • Masaharu Ito
    • 5
  • Yasushi Matsuzaki
    • 6
  • Hajime Ohmori
    • 1
  1. 1.Graduate School of Comprehensive Human SciencesUniversity of TsukubaTsukubaJapan
  2. 2.Joint Research CenterTokyo Medical University Ibaraki Medical CenterAmiJapan
  3. 3.Sports Research and Development CoreUniversity of TsukubaTsukubaJapan
  4. 4.School of Health and Physical EducationUniversity of TsukubaTsukubaJapan
  5. 5.Livence Co. Inc.ChuoJapan
  6. 6.Division of Gastroenterology and Hepatology, Department of Internal MedicineTokyo Medical University Ibaraki Medical CenterAmiJapan

Personalised recommendations