Infectious Disease Modeling

  • Angela R. McLeanEmail author


Infectious disease models are mathematical descriptions of the spread of infection. The majority of infectious disease models consider the spread of infection from one host to another and are sometimes grouped together as “mathematical epidemiology.” A growing body of work considers the spread of infection within an individual, often with a particular focus on interactions between the infectious agent and the host’s immune responses. Such models are sometimes grouped together as “within-host models.” Most recently, new models have been developed that consider host–pathogen interactions at two levels simultaneously: both within-host dynamics and between-host transmissions. Infectious disease models vary widely in their complexity, in their attempts to refer to data from real-life infections and in their focus on problems of an applied or more fundamental nature. This entry will focus on simpler models tightly tied to data and aimed at addressing well-defined practical problems.


Secondary Case Escape Mutant Capita Rate Basic Reproductive Number Rubella Vaccination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Basic reproductive number

A summary parameter that encapsulates the infectiousness of an infectious agent circulating in a population of hosts.


An organism that acts as the environment within which an infectious agent replicates.

Infectious agent

A microorganism that replicates inside another organism.


An infectious agent that damages its host.


One of several types of an infectious agent, often closely related to and sometimes evolved from other variants under consideration.


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Books and Reviews

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Zoology Department, Institute of Emerging InfectionsUniversity of OxfordOxfordUK

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