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MSCs for Induction of Solid Organ Allograft Acceptance

  • Marc Dahlke
  • Philipp Renner
  • Elke Eggenhofer
Chapter
Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Abstract

Over the past four decades, the transplantation of solid organs (liver, kidney, heart, pancreas, and lung) has become standard clinical therapy. Despite its overall success, the shortage of donor organs and the need for lifelong immunosuppression continue to pose major challenges that need to be addressed. This chapter summarizes the preclinical efforts undertaken to investigate the potential use of mesenchymal stromal cells in the field of solid organ transplantation and presents insights into the concepts of ongoing early clinical studies.

Keywords

Graft Survival Mesenchymal Stromal Cell Solid Organ Transplantation Allograft Survival Multipotent Adult Progenitor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of SurgeryUniversity Medical Center RegensburgRegensburgGermany

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