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Biology of Bone Cancer Pain

  • Chapter
Metastatic Bone Disease

Abstract

Bone cancer pain is a complex process with many potential targets for therapeutic intervention. As pain is the most common presenting symptom in patients with skeletal metastases and is directly proportional to the patient’s quality of life, clinical advancements in the treatment of bone cancer pain are of the utmost importance. Research targeting pain-related cytokines, anti-osteoclastic medications, and ion channels has shown significant clinical progress in the treatment of cancer-related bone pain. With continued efforts into these and other therapeutic strategies, we hope to continue to improve the quality of life of those patients suffering with bone cancer pain.

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Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, University of Kentucky, 740 S. Limestone Ave., Lexington, KY, 40536, USA

    Patrick W. O’Donnell MD, PhD

  2. Department of Orthopaedic Surgery and Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

    Denis R. Clohisy MD

Authors
  1. Patrick W. O’Donnell MD, PhD
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  2. Denis R. Clohisy MD
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Corresponding author

Correspondence to Patrick W. O’Donnell MD, PhD .

Editor information

Editors and Affiliations

  1. Huntsman Cancer Institute, The University of Utah, Salt Lake City, Utah, USA

    R. Lor Randall

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© 2016 Springer Science+Business Media New York

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O’Donnell, P.W., Clohisy, D.R. (2016). Biology of Bone Cancer Pain. In: Randall, R. (eds) Metastatic Bone Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5662-9_3

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  • DOI: https://doi.org/10.1007/978-1-4614-5662-9_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-5661-2

  • Online ISBN: 978-1-4614-5662-9

  • eBook Packages: MedicineMedicine (R0)

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