Abstract
Commensal and opportunistic pathogens that populate the respiratory tract evolve within the host in response to the innate and adaptive immune clearance mechanisms. Pseudomonas aeruginosa, an opportunist, is not normally a component of the airway flora but is ubiquitous in the environment and especially common in health care-associated facilities (Crit Care Med 27:887ā892, 1999; Chest 119:373Sā384S, 2001). Although the focus of this review is not upon the pathogenesis of P. aeruginosa infection in cystic fibrosis (CF), there are substantial data examining host innate immune signaling in response to this organism in CF as compared to normal cells
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Cohen, T.S. (2013). Pseudomonas aeruginosa and Mucosal Defenses in the Lung. In: Prince, A. (eds) Mucosal Immunology of Acute Bacterial Pneumonia. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5326-0_11
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