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Head and Neck Cancer

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60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center

Abstract

Head and neck cancer (HNC) is a devastating disease that affects some of the most basic daily functions such as breathing, speaking, and swallowing. Because of its visible nature, HNC is also associated with significant disfigurement. The combined effect of disability and disfigurement and the added toxicity of treatment greatly increase symptom burden and reduce physical, emotional, and social functioning. Since its inception, the Head and Neck Oncology Program at MD Anderson Cancer Center has pioneered multidisciplinary care with the main goal of improving survival and reducing suffering in patients with HNC. Over the past 60 years, significant advances have been made in the treatment and rehabilitation of patients with HNC, resulting in improved disease control, survival, and organ preservation. The purpose of this chapter is to highlight some of the advances in treatment and improvements in outcome of patients with HNC treated in the Head and Neck Multidisciplinary Care Center at MD Anderson.

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Author information

Authors and Affiliations

  1. Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77025, USA

    Ehab Hanna & Randal Weber

  2. Department of Thoracic Head and Neck Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Bonnie Glisson

  3. Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Kian Ang

Authors
  1. Ehab Hanna
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  2. Bonnie Glisson
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  3. Kian Ang
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  4. Randal Weber
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Corresponding author

Correspondence to Ehab Hanna .

Editor information

Editors and Affiliations

  1. Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    M. Alma Rodriguez

  2. Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    Ronald S. Walters

  3. Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    Thomas W. Burke

Appendix

Appendix

See Figs. 25.8 through 25.27.

Fig. 25.8
figure 00258

Survival rates for patients with local (SEER stage) cancer of the head and neck with oral cavity primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

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Fig. 25.9
figure 00259

Survival rates for patients with regional (SEER stage) cancer of the head and neck with oral cavity primary sites (1944–2004) (P  =  0.001, log-rank test for trend).

Full size image
Fig. 25.10
figure 002510

Survival rates for patients with distant (SEER stage) cancer of the head and neck with oral cavity primary sites (1944–2004) (P  =  0.062, log-rank test for trend).

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Fig. 25.11
figure 002511

Survival rates for patients with local (SEER stage) cancer of the head and neck with oropharyngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

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Fig. 25.12
figure 002512

Survival rates for patients with regional (SEER stage) cancer of the head and neck with oropharyngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

Full size image
Fig. 25.13
figure 002513

Survival rates for patients with distant (SEER stage) cancer of the head and neck with oropharyngeal primary sites (1944–2004) (P  <  0.159, log-rank test for trend). Because of the very small number of individuals with distant cancer of the head and neck with oropharyngeal primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

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Fig. 25.14
figure 002514

Survival rates for patients with local (SEER stage) cancer of the head and neck with laryngeal primary sites (1944–2004) (P  =  0.645, log-rank test for trend).

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Fig. 25.15
figure 002515

Survival rates for patients with regional (SEER stage) cancer of the head and neck with laryngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

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Fig. 25.16
figure 002516

Survival rates for patients with distant (SEER stage) cancer of the head and neck with laryngeal primary sites (1944–2004) (P  =  0.027, log-rank test for trend). Because of the very small number of individuals with distant cancer of the head and neck with laryngeal primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

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Fig. 25.17
figure 002517

Survival rates for patients with local (SEER stage) cancer of the head and neck with paranasal sinus and nasal cavity primary sites (1944–2004) (P  =  0.166, log-rank test for trend). Because of the very small number of individuals with local cancer of the head and neck with paranasal sinus and nasal cavity primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

Full size image
Fig. 25.18
figure 002518

Survival rates for patients with regional (SEER stage) cancer of the head and neck with paranasal sinus and nasal cavity primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

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Fig. 25.19
figure 002519

Survival rates for patients with distant (SEER stage) cancer of the head and neck with paranasal sinus and nasal cavity primary sites (1944–2004) (P  =  0.001, log-rank test for trend). Because of the very small number of individuals with distant cancer of the head and neck with paranasal sinus and nasal cavity primary sites seen from 1944 to 1954 and from 1955 to 1964, data from these periods were excluded. N.A. not applicable.

Full size image
Fig. 25.20
figure 002520

Overall rates for patients with cancer of the head and neck with nasopharyngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

Full size image
Fig. 25.21
figure 002521

Survival rates for patients with local (SEER stage) cancer of the head and neck with nasopharyngeal primary sites (1944–2004) (P  =  0.153, log-rank test for trend). Because of the very small number of individuals with local cancer of the head and neck with nasopharyngeal primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

Full size image
Fig. 25.22
figure 002522

Survival rates for patients with regional (SEER stage) cancer of the head and neck with nasopharyngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend).

Full size image
Fig. 25.23
figure 002523

Survival rates for patients with distant (SEER stage) cancer of the head and neck with nasopharyngeal primary sites (1944–2004) (P  <  0.0001, log-rank test for trend). Because of the very small number of individuals with distant cancer of the head and neck with nasopharyngeal primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

Full size image
Fig. 25.24
figure 002524

Overall rates for patients with cancer of the head and neck with hypopharyngeal primary sites (1944–2004) (P  =  0.020, log-rank test for trend).

Full size image
Fig. 25.25
figure 002525

Survival rates for patients with local (SEER stage) cancer of the head and neck with hypopharyngeal primary sites (1944–2004) (P  =  0.375, log-rank test for trend). Because of the very small number of individuals with local cancer of the head and neck with hypopharyngeal primary sites seen from 1944 to 1954, from 1955 to 1964, from 1965 to 1974, and from 1995 to 2004, data from these periods were excluded. N.A. not applicable.

Full size image
Fig. 25.26
figure 002526

Survival rates for patients with regional (SEER stage) cancer of the head and neck with hypopharyngeal primary sites (1944–2004) (P  =  0.246, log-rank test for trend).

Full size image
Fig. 25.27
figure 002527

Survival rates for patients with distant (SEER stage) cancer of the head and neck with hypopharyngeal primary sites (1944–2004) (P  =  0.358, log-rank test for trend). Because of the very small number of individuals with distant cancer of the head and neck with hypopharyngeal primary sites seen from 1944 to 1954, data from this period were excluded. N.A. not applicable.

Full size image

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Hanna, E., Glisson, B., Ang, K., Weber, R. (2013). Head and Neck Cancer. In: Rodriguez, M., Walters, R., Burke, T. (eds) 60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5197-6_25

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  • DOI: https://doi.org/10.1007/978-1-4614-5197-6_25

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