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Acute Kidney Injury After Liver Transplantation

  • Raymond M. Planinsic
  • Tetsuro Sakai
  • Ibtesam A. Hilmi
Chapter

Abstract

The incidence of postoperative renal insufficiency and acute kidney injury (AKI) in patients undergoing liver transplantation ranges from 20 % up to 90 % [1] and more than 80 % of these episodes occur within the first 2 postoperative days. Earlier studies found that mortality at 30 days was 50 % in patients who developed AKI and 29 % in non-AKI patients [2]. AKI necessitating renal replacement therapy has been associated with mortality rates from 55 to 90 % [3]. Risk factors for the development of AKI in these patients include preoperative renal dysfunction represented with a higher preoperative serum creatinine (SCrea), greater requirements for intraoperative blood transfusion, more frequent episodes of intraoperative hypotension, and other preexisting comorbidities [2].

Keywords

Liver Transplantation Renal Replacement Therapy Acute Kidney Injury Renal Injury Hemolytic Uremic Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Raymond M. Planinsic
    • 1
  • Tetsuro Sakai
    • 2
  • Ibtesam A. Hilmi
    • 3
  1. 1.Department of AnesthesiologyUniversity of Pittsburgh Medical CenterPittsburghUSA
  2. 2.Department of AnesthesiologyUniversity of Pittsburgh School of MedicinePittsburghUSA
  3. 3.Department of AnesthesiologyUPMC PresbyterianPittsburghUSA

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