Drug Eruptions

  • Rita V. Patel
  • Gary Goldenberg


Cutaneous reactions are the most frequently occurring adverse reactions to drugs. These reactions can range from mild (two-thirds of cases) to life-threatening (one-third of cases) in the hospital setting [1, 2]. Distinguishing a mild versus a life-threatening reaction is challenging, yet critical, in the management of drug allergies. Cutaneous manifestations are frequently the earliest signs of a systemic drug allergy and can provide information on the severity and prognosis of an allergic reaction [3]. Numerous risk factors predispose patients to severe cutaneous drug reactions, including immunosuppression (especially infection with human immunodeficiency virus) [4] or mononucleosis [5], female gender [6], number of drugs being taken, and elderly age [7].


Toxic Epidermal Necrolysis Drug Eruption Erythema Multiforme Serum Sickness Pustular Psoriasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of DermatolgoyMount Sinai School of MedicineNew YorkUSA

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