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Nanotechnology to Enhance Electron Transfer

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Bio/CMOS Interfaces and Co-Design

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Abstract

We saw in Chap. 4 how different macromolecules interact with each other due to their specific functions in biology. Chapter 7 showed how to translate their interactions into an electrical signal for biosensing of DNA. In this chapter, we see how to translate the specific interactions into an electrical signal for biosensing with enzyme-based detection. We also saw in Chap. 6 how to use nanotechnology to decrease electrical signals coming from nonspecific interactions occurring at an interface. In this chapter, we will see how to use nanotechnology to increase the electrical signals coming from specific interactions at the Bio/CMOS interface between enzymes and their substrates.

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Further Reading

  1. Bard AJ, Faulkner LR (2011) Electrochemical methods – fundamentals and applications, 2nd edn. Wiley, New York

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  2. Carrara S (2011) Nano-bio-sensing. Springer, New York

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  3. Mose CC, Kesek JM, Warncke K, Farid RS, Dutton PL (1992) Nature of biological electron transfer. Nature 355:796–812

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  4. Gooding JJ (2005) Nanostructuring electrodes with carbon nanotubes: a review on electrochemistry and applications for sensing. Electrochim Acta 50:3049–3060

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  5. Carrara S, Bavastrello V, Ricci D, Stura E, Nicolini C (2005) Improved nanocomposite materials for biosensor applications investigated by impedance spectroscopy. Sensor Actuator B Chem 109:221–226

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  6. Carrara S, Shumyantseva VV, Archakov AI, Samorì B (2008) Screen-printed electrodes based on carbon nanotubes and cytochrome p450scc for highly-sensitive cholesterol biosensors. Biosens Bioelectron 24:148–150

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  7. Boero C, Carrara S, Del Vecchio G, Calzà L, De Micheli G (2011) Highly-sensitive carbon nanotubes-based sensing for glucose and lactate monitoring in cell culture. IEEE Trans Nanobiology 10:59–67

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Authors and Affiliations

  1. Faculties Sciences et Techniques de l’Ingénieur and Informatique et Communications Labo. Systèmes Intégrés (LSI), Lausanne, Switzerland

    Sandro Carrara

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  1. Sandro Carrara
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© 2013 Springer Science+Business Media New York

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Carrara, S. (2013). Nanotechnology to Enhance Electron Transfer. In: Bio/CMOS Interfaces and Co-Design. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4690-3_8

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  • DOI: https://doi.org/10.1007/978-1-4614-4690-3_8

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-4689-7

  • Online ISBN: 978-1-4614-4690-3

  • eBook Packages: EngineeringEngineering (R0)

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