Abstract
Perhaps one of the most important topics in splenic pathology is lymphoid neoplasms. A wide variety of lymphomas can be seen in the spleen. These can be divided in several ways including cell derivation (T versus B), pattern of involvement (red pulp, white pulp, mixed, masses), or as predominantly diagnosed in spleen versus manifestations of systemic lymphomas. Lymphomas that predominantly involve the white pulp illustrated are splenic marginal zone lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, lymphoplasmacytic lymphoma, follicular lymphoma, mantle cell lymphoma, and plasma cell disorders. Lymphomas presenting in red pulp that are illustrated include hairy cell leukemia, hairy cell leukemia-variant, splenic diffuse red pulp B-cell lymphoma, B-cell prolymphocytic leukemia/lymphoma, acute lymphoblastic leukemia/lymphoma, hepatosplenic T-cell lymphoma, T-cell large granular lymphocytic leukemia, and other T cell lymphomas. In addition, other lymphomas illustrated include diffuse large B-cell lymphoma and variants, classical Hodgkin lymphoma, and nodular lymphocyte-predominant Hodgkin lymphoma. When appropriate, immunohistochemical staining, gross images and other sites of presentation (peripheral blood, bone marrow) are illustrated.
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© 2013 Springer Science+Business Media New York
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O’Malley, D.P. (2013). Lymphoid Neoplasms. In: Atlas of Spleen Pathology. Atlas of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4672-9_3
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DOI: https://doi.org/10.1007/978-1-4614-4672-9_3
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