Morphologic Observations on Experimental Atherosclerosis in SEA Japanese Quail
The Japanese quail has been considered useful for the study of experimental atherosclerosis since the original reports of Ojerio et al. (1) and of Smith and Hilker (2). However, in the use of these not selectively bred animals the appearance of gross lesions was not uniform or took up to 28 months for their production. Furthermore, microscopic examination of the lesions was totally or practically neglected.
KeywordsCholesterol Migration Foam Citrate Luminal
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- 1.Ojerio, A.D., G.J. Pucak, T.B. Clarkson and B.C. Bullock. 1972. Diet-induced atherosclerosis and myocardial infarction in Japanese quail. Lab. Animal Sci. 22:33–39.Google Scholar
- 3.Chapman, K.P., W.W. Stafford and C.E. Day. 1976. Animal model for experimental atherosclerosis produced by selective breeding of Japanese quail. In: Atherosclerosis Drug Discovery, ed. by C.E. Day, Plenum Press, New York. pp. 347–356.Google Scholar
- 4.McGill, H.C., Jr. and J.C. Geer. 1963. The human lesion, fine structure. In: Evolution of the Atherosclerotic Plaque, ed. by R.J. Jones, University of Chicago Press, Chicago, pp. 65–76.Google Scholar
- 8.Geer, J.C. and M.D. Haust. 1972. Smooth Muscle Cells in Atherosclerosis. S. Karger, Basel.Google Scholar