Fate and Localization of Iodine-Labelled HCG in Mice

  • Aliza Eshkol
  • B. Lunenfeld
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 2)


It has been shown in the past that labelling of human chorionic gonadotropin (HCG) with 1 – 2 atoms of radioactive iodine does not affect the biological, immunological and physicochemical behaviour of the hormone. (1). Furthermore, it has been established that the ovary, more than any other organ, has a capacity to concentrate HCG, and this is specific for the gonadotropic hormone. Labelled albumin or iodide were not concentrated by the ovary even when the animals were stimulated simultaneously with unlabelled HCG (1, 2).


Human Chorionic Gona Specific Period Radioactive Iodine Follicular Development Theca Cell 


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  1. 1.
    Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165Google Scholar
  2. 2.
    Eshkol, A. In: Recent Research on Gonadotropinc Hormones, eds. E.T. Bell and J. A. Loraine, Edinburgh, Livingstone (1967), p. 202.Google Scholar
  3. 3.
    Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967)6:4.Google Scholar

Copyright information

© Springer Science+Business Media New York 1968

Authors and Affiliations

  • Aliza Eshkol
    • 1
  • B. Lunenfeld
    • 1
  1. 1.Institute of EndocrinologyTel-Hashomer Government, HospitalIsrael

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