Skip to main content

Nutrition

  • Chapter
  • First Online:

Abstract

Mr. N is a 54-year-old man with a history of hypertension, coronary disease, peripheral vascular disease, gout, dyslipidemia, and chronic kidney disease (CKD) Stage III (MDRD eGFR 35 mL/min) who presents with a 10 kg weight gain over the last 2 months. The patient reports that he has not been very compliant with his diet or exercise program. Gout attacks have been frequent. Physical exam: Height 5′9″; Weight 97 kg, 213 lb; BMI 31. The patient has 7 cm JVD at 30° and 1+ bilateral lower extremity edema. The exam is otherwise unremarkable. Significant labs: creatinine 2.3 mg/dL, triglycerides: 346 mg/dL, serum bicarbonate: 19 mEq/L, potassium: 5.7 mEq/L, phosphorus: 5.5 mg/dL, and PTH: 220 pg/dL. Despite the presence of volume overload, his blood urea nitrogen (BUN) to Cr ratio is 20:1. The patient also has proteinuria (albumin to creatinine ratio: 830 μg/mg).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   179.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   229.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Bailey JL, Franch H. Nutritional considerations in kidney disease: core curriculum 2010. Am J Kidney Dis. 2010;55(6):1146–61.

    Article  PubMed  Google Scholar 

  2. Saab G, Whaley-Connell AT, McCullough PA, Bakris GL. CKD awareness in the United States: the kidney early evaluation. Program (KEEP). Am J Kidney Dis. 2008;52:382–3.

    Article  PubMed  Google Scholar 

  3. Fouque D, Kalantar-Zadeh K, Kopple J, et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int. 2008;73(4):391–8.

    Article  PubMed  CAS  Google Scholar 

  4. Teta D. Weight loss in obese patients with chronic kidney disease: who and how? J Ren Care. 2010;36 Suppl 1:163–71.

    Article  PubMed  Google Scholar 

  5. Navaneethan SD, Yehnert H, Moustarah F, Schreiber MJ, Schauer PR, Beddhu S. Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2009;4(10):1565–74.

    Article  PubMed  Google Scholar 

  6. Chanutin A, Ferris EB. Experimental renal insufficiency produced by partial nephrectomy I. Control diet. Arch Intern Med. 1932;49:767–87.

    Article  CAS  Google Scholar 

  7. Chanutin A, Ludewig S. Experimental renal insufficiency produced by partial nephrectomy. V. Diets containing whole dried meat. Arch Intern Med. 1936;58:60–80.

    Article  CAS  Google Scholar 

  8. Franch HA, Mitch WE. Navigating between the Scylla and Charybdis of prescribing dietary protein for chronic kidney diseases. Annu Rev Nutr. 2009;29:341–64.

    Article  PubMed  CAS  Google Scholar 

  9. Kontessis P, Jones S, Dodds R, et al. Renal, metabolic and hormonal responses to ingestion of animal and vegetable proteins. Kidney Int. 1990;38:136.

    Article  PubMed  CAS  Google Scholar 

  10. Kopple JD. National kidney foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure. Am J Kidney Dis. 2001;37(1 Suppl 2):S66–70.

    Article  PubMed  CAS  Google Scholar 

  11. Kopple JD. Pathophysiology of protein-energy wasting in chronic renal failure. J Nutr. 1999;129(1S Suppl):247–51.

    Google Scholar 

  12. Kaysen GA. Lipid and lipoprotein metabolism in chronic kidney disease. J Ren Nutr. 2009;19(1):73–7.

    Article  PubMed  CAS  Google Scholar 

  13. Beto JA, Bansal VK. Medical nutrition therapy in chronic kidney failure: integrating clinical practice guidelines. J Am Diet Assoc. 2004;104(3):404–9.

    Article  PubMed  Google Scholar 

  14. Axelsson TG, Irving GF, Axelsson J. To eat or not to eat: dietary fat in uremia is the question. Semin Dial. 2010;23(4):383–8.

    Article  PubMed  Google Scholar 

  15. O’Seaghdha CM, Hwang SJ, Muntner P, et al. Serum phosphorus predicts incident chronic kidney disease and end-stage renal disease. Nephrol Dial Transplant. 2011;26(9):2885–90. doi:10.1093/ndt/gfq808.

    Article  PubMed  Google Scholar 

  16. Martin KJ, Gonzalez EA. Prevention and control of phosphate retention/hyperphosphatemia in CKD-MBD: what is normal, when to start, and how to treat? Clin J Am Soc Nephrol. 2011;6(2):440–6.

    Article  PubMed  Google Scholar 

  17. Eknoyan G, Levin A, Levin NW. Bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003;42 Suppl 3:1–201.

    Article  Google Scholar 

  18. Peacock M. Calcium metabolism in health and disease. Clin J Am Soc Nephrol. 2010;5 Suppl 1:S23–30.

    Article  PubMed  CAS  Google Scholar 

  19. Krikken JA, Laverman GD, Navis G. Benefits of dietary sodium restriction in the management of chronic kidney disease. Curr Opin Nephrol Hypertens. 2009;18(6):531–8.

    Article  PubMed  CAS  Google Scholar 

  20. World Health Organization. Reducing salt intake in populations: report of a WHO forum and technical meeting. 2006; Paris, France.

    Google Scholar 

  21. Klaus D, Hoyer J, Middeke M. Salt restriction for the prevention of cardiovascular disease. Dtsch Arztebl Int. 2010;107(26):457–62.

    PubMed  Google Scholar 

  22. Palmer BF. A physiologic-based approach to the evaluation of a patient with hyperkalemia. Am J Kidney Dis. 2010;56(2):387–93.

    Article  PubMed  Google Scholar 

  23. Korgaonkar S, Tilea A, Gillespie BW, et al. Serum potassium and outcomes in CKD: insights from the RRI-CKD cohort study. Clin J Am Soc Nephrol. 2010;5(5):762–9.

    Article  PubMed  CAS  Google Scholar 

  24. Spiegel D. Magnesium in chronic kidney disease: unanswered questions. Blood Purif. 2011;31:172–6.

    Article  PubMed  CAS  Google Scholar 

  25. Lobo JC, Torres JPM, Fouque D, et al. Zinc deficiency in chronic kidney disease: a relationship with adipose tissue and atherosclerosis? Biol Trace Elem Res. 2010;135:16–21.

    Article  PubMed  CAS  Google Scholar 

  26. Oakes EJ, Lyon TD, Duncan A, et al. Acute inflammatory response does not affect erythrocyte concentrations of copper, zinc and selenium. Clin Nutr. 2008;27:115.

    Article  PubMed  CAS  Google Scholar 

  27. Hsieh YY, Shen WS, Lee LY, et al. Long-term changes in trace elements in patients undergoing chronic hemodialysis. Biol Trace Elem Res. 2006;109(2): 115–21.

    Article  PubMed  CAS  Google Scholar 

  28. Handelman GJ, Levin NW. Guidelines for vitamin supplements in chronic kidney disease patients: what is the evidence? J Ren Nutr. 2011;21(1):117–9.

    Article  PubMed  CAS  Google Scholar 

  29. Fissell RB, Bragg-Gresham JL, Gillespie BW, et al. International variation in vitamin prescription and association with mortality in the dialysis outcomes and practice patterns study (DOPPS). Am J Kidney Dis. 2004;44:293–9.

    Article  PubMed  CAS  Google Scholar 

  30. Bossola M, Tazza L, Giungi S, et al. Anorexia in hemodialysis patients: an update. Kidney Int. 2006;70:417–22.

    PubMed  CAS  Google Scholar 

  31. Akpele L, Bailey JL. Nutrition counseling impacts serum albumin levels. J Ren Nutr. 2004;14:143–8.

    Article  PubMed  Google Scholar 

  32. American Heart Association Nutrition Committee, Lichtenstein AH, Appel LJ, et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation. 2006;114(1):82–96.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sejal P. Sarolia M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this chapter

Cite this chapter

Sarolia, S.P., Franch, H.A. (2013). Nutrition. In: Lerma, E., Rosner, M. (eds) Clinical Decisions in Nephrology, Hypertension and Kidney Transplantation. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4454-1_27

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-4454-1_27

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-4453-4

  • Online ISBN: 978-1-4614-4454-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics