Fat: Beyond Energy Storage

  • Milind Watve


The rapidly increasing epidemic of obesity has stimulated substantial research focused on fat metabolism. For the alternative model of T2D and related disorders that this book is developing, obesity is not as important and essential as the classical model presumes. By now the new argument is sufficiently clear on its stand on the relationship between obesity and T2D although a part of it is yet to be discussed. In the new emerging picture obesity is not causal to insulin resistance and T2D, but the behavioral factors that cause obesity and those that cause insulin resistance are largely overlapping. Therefore the association between obesity and insulin resistance leading to T2D is not surprising. But it is also not obligate. Physiologically it is possible (and also common in some populations) to be insulin resistant and eventually diabetic without ever being obese. Similarly it is also possible to be obese and still insulin sensitive. The two are independent but largely overlapping etho-physiological states. We will now examine this statement more elaborately starting for the basic functions of fat and why fat metabolism is linked with a diversity of other functions in the body.


Insulin Resistance Food Intake Physical Aggression Basal Metabolic Rate Energy Balance Equation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Milind Watve
    • 1
  1. 1.Indian Institute of Science Education and Research Pune (IISER-P)PuneIndia

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