The uveal tract comprises the iris, the ciliary body, and the choroid, each of which has distinct histological features.
A significant component of uveal tract pathology derives from its population of indigenous melanocytes. The majority of the eyes enucleated for a uveal lesion that you are likely to see on the surgical pathology bench are malignant melanoma.
This chapter will focus on uveal melanoma and two other less common tumors: ciliary body medulloepithelioma and melanocytoma (also known as the magnocellular nevus).
A few other lesions that enter the differential diagnosis will also be introduced.