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Proteins and Macromolecular X-Ray Analysis

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Structure Determination by X-ray Crystallography

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Abstract

In this chapter, we take a more detailed look at methods of X-ray analysis that are particularly applicable to large biological molecules. It will involve some useful reiteration of concepts and ideas discussed in previous chapters. We would also remind readers that although there are definite distinctions between large and small molecules in the crystallographic arena, there is no reason to exclude one from the other, and in fact, there are many advantages in being familiar with both. The major differences should become clearer as we progress through this chapter. It follows that while we deal mainly with macromolecules here, much of the information provided in this chapter is applicable to all areas of crystal structure analysis.

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Author information

Authors and Affiliations

  1. University of Surrey, Guildford, England

    Mark Ladd (Formerly Head of Chemical Physics)

  2. Birkbeck College, University of London, London, England

    Rex Palmer (Reader Emeritus in Structural Crystallography, Visiting Professor in X-ray Crystallography, Senior Visiting Research Fellow)

  3. University of Greenwich, London, England

    Rex Palmer (Reader Emeritus in Structural Crystallography, Visiting Professor in X-ray Crystallography, Senior Visiting Research Fellow)

  4. Christ Church University, Canterbury, England

    Rex Palmer (Reader Emeritus in Structural Crystallography, Visiting Professor in X-ray Crystallography, Senior Visiting Research Fellow)

Authors
  1. Mark Ladd
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  2. Rex Palmer
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Ladd, M., Palmer, R. (2013). Proteins and Macromolecular X-Ray Analysis. In: Structure Determination by X-ray Crystallography. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-3954-7_10

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