Diagnostic Immunohistochemistry in Tumor Metastasis
Immunohistochemistry (IHC) refers to the process of localizing antigens (e.g. proteins) in cells of a tissue section using antibodies that bind specifically to these antigens in bisological tissues Ramos-Vara (Vet Pathol 42:405–426, 2005). Immunohistochemical staining is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors and in metastasis Webster et al. (J Histochem Cytochem 57:753–761, 2009).
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