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Hematogenous Dissemination

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Abstract

The changes in the ECM composition induced by the invading tumor cells have been discussed in previous chapters. We now focus on the following step of the metastatic cascade, the access of malignant cells to the host’s bloodstream. The importance of understanding this early step of disease progression is crucial because most cancer patients die from metastases rather than from their primary tumors.

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Authors and Affiliations

  1. Department of Ophthalmology & Pathology, Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Canada

    Bruno F. Fernandes MD, PhD

Authors
  1. Bruno F. Fernandes MD, PhD
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Correspondence to Bruno F. Fernandes MD, PhD .

Editor information

Editors and Affiliations

  1. Centre for Genomic Regulation, N/A, Barcelona, N/A, Spain

    Julia V. Burnier

  2. , Ophthalmology, Pathology, Medicine & Onc, McGill University Health Centre, University Street 3775, Montreal, H3A 2B4, Québec, Canada

    Miguel N. Burnier, Jr.

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Fernandes, B. (2013). Hematogenous Dissemination. In: Burnier, J., Burnier, Jr., M. (eds) Experimental and Clinical Metastasis. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3685-0_13

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