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Episodic and Semantic Memory Disorders

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Handbook on the Neuropsychology of Aging and Dementia

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Abstract

In its most pure form, the human amnesic syndrome involves a disabling impairment in new learning accompanied by some degree of impairment in aspects of remote memory in the context of relatively normal intellectual ability, language, and attention span. Neuropsychological research has clearly shown that lesions within the brain’s extended memory system (medial temporal lobe, diencephalon, and basal forebrain) produce anterograde amnesia while leaving other aspects of memory (retrieval of general knowledge, vocabulary, names) relatively intact. The episodic–semantic distinction has been useful in explaining key characteristics of the human amnesic syndrome. This chapter provides a framework for characterizing the distinction between “episodic” and “semantic” memory, and discusses the clinical features and assessment of disordered function in each of these two domains.

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References

  1. James W. The principles of psychology. New York: Dover; 1890.

    Google Scholar 

  2. Hebb DO. The organization of behavior: a neuropsychological theory. New York: Wiley; 1949.

    Google Scholar 

  3. Tulving E. Episodic and semantic memory. In: Tulving E, Donaldson W, editors. Organization of memory. New York: Academic; 1972. p. 381–403.

    Google Scholar 

  4. Cermak LS. The episodic-semantic distinction in amnesia. In: Squire L, Butters N, editors. Neuropsychology of memory. New York: Guilford Press; 1984. p. 55–62.

    Google Scholar 

  5. Kinsbourne M, Wood F. Short-term memory processes and the amnesic syndrome. In: Deutsch D, Deutsch JA, editors. Short-term memory. New York: Academic; 1975. p. 258–91.

    Google Scholar 

  6. Weingartner H, Grafman J, Boutelle W, Kaye W, Martin P. Forms of cognitive failure. Science. 1983;221:380–2.

    PubMed  Google Scholar 

  7. Bauer R, Reckess G, Kumar A, Valenstein E. Amnesic disorders. In: Heilman KM, Valenstein E, editors. Clinical neuropsychology. 5th ed. New York: Oxford University Press; 2011.

    Google Scholar 

  8. Moscotitch M, Rosenbaum RS, Gilboa A, Addis DR, Westmacott R, Grady CL, et al. Functional neuroanatomy of remote episodic, semantic, and spatial memory: A unified account based on multiple trace theory. Journal of Anatomy. 2005;207:35–66.

    Google Scholar 

  9. Steinvorth S, Levine B, Corkin S. Medial temporal lobe structures are needed to re-experience remote autobiographical memories: Evidence from H.M. & W.R. Neuropsychologia. 2005;43:479–96.

    Google Scholar 

  10. De Renzi E, Liotti M, Nichelli P. Semantic amnesia with preservation of autobiographic memory. A case report. Cortex. 1987;23(4):575–97.

    PubMed  Google Scholar 

  11. Grossi D, Trojano L, Grasso A, Orsini A. Selective “semantic amnesia” after closed-head injury. A case report. Cortex. 1988;24(3):457–64.

    PubMed  Google Scholar 

  12. Yasuda K, Watanabe O, Ono Y. Dissociation between semantic and autobiographic memory: a case report. Cortex. 1997;33(4):623–38.

    PubMed  Google Scholar 

  13. Carlesimo GA, Sabbadini M, Loasses A, Caltagirone C. Analysis of the memory impairment in a post-encephalitic patient with focal retrograde amnesia. Cortex. 1998;34(3):449–60.

    PubMed  Google Scholar 

  14. Hodges JR, McCarthy RA. Loss of remote memory: a cognitive neuropsychological perspective. Curr Opin Neurobiol. 1995;5(2):178–83.

    PubMed  Google Scholar 

  15. Hunkin NM, Parkin AJ, Bradley VA, Burrows EH, Aldrich FK, Jansari A, Burdon-Cooper C. Focal retrograde amnesia following closed head injury: a case study and theoretical account. Neuropsychologia. 1995;33(4):509–23.

    PubMed  Google Scholar 

  16. Kapur N, Ellison D, Smith MP, McLellan DL, Burrows EH. Focal retrograde amnesia following bilateral temporal lobe pathology. A neuropsychological and magnetic resonance study. Brain. 1992;115(Pt 1):73–85.

    PubMed  Google Scholar 

  17. Kapur N, Young A, Bateman D, Kennedy P. Focal retrograde amnesia: a long term clinical and neuropsychological follow-up. Cortex. 1989;25(3):387–402.

    PubMed  Google Scholar 

  18. Markowitsch HJ, Calabrese P, Neufeld H, Gehlen W, Durwen HF. Retrograde amnesia for world knowledge and preserved memory for autobiographic events. A case report. Cortex. 1999;35(2):243–52.

    PubMed  Google Scholar 

  19. O’Connor M, Butters N, Miliotis P, Eslinger P, Cermak LS. The dissociation of anterograde and retrograde amnesia in a patient with herpes encephalitis. J Clin Exp Neuropsychol. 1992;14(2):159–78.

    PubMed  Google Scholar 

  20. Kapur N. Syndromes of retrograde amnesia: a conceptual and empirical synthesis. Psychol Bull. 1999;125(6):800–25.

    PubMed  Google Scholar 

  21. Vargha-Khadem F, Gadian DG, Watkins KE, Connelly A, Van Paesschen W, Mishkin M. Differential effects of early hippocampal pathology on episodic and semantic memory. Science. 1997;277(5324):376–80.

    PubMed  Google Scholar 

  22. Butters N, Granholm E, Salmon E, Grant I, Wolfe J. Episodic and semantic memory: a comparison of amnesic and demented patients. J Exp Clin Neuropsychol. 1987;9:479–97.

    Google Scholar 

  23. Cermak LS, Reale L, Baker E. Alcoholic Korsakoff patients’ retrieval from semantic memory. Brain Lang. 1978;5:215–26.

    PubMed  Google Scholar 

  24. Squire LR, Zola SM. Episodic memory, semantic memory, and amnesia. Hippocampus. 1998;8(3):205–11.

    PubMed  Google Scholar 

  25. Verfaellie M, Cermak LS. Acquisition of generic memory in amnesia. Cortex. 1994;30(2):293–303.

    PubMed  Google Scholar 

  26. Zola-Morgan S, Cohen NJ, Squire LR. Recall of remote episodic memory in amnesia. Neuropsychologia. 1983;21:487–500.

    PubMed  Google Scholar 

  27. Schacter DL, Wagner AD, Buckner RL. Memory systems of 1999. In: Tulving E, Craik FIM, editors. The Oxford handbook of memory. New York: Oxford University Press; 2000. p. 627–43.

    Google Scholar 

  28. Loftus EF, Cole W. Retrieving attribute and name information from semantic memory. J Exp Psychol. 1974;102:1116–22.

    Google Scholar 

  29. Petersen RC, Stevens J, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST. Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56:1133–42.

    PubMed  Google Scholar 

  30. Petersen RC. Mild cognitive impairment: aging to Alzheimer’s disease. New York: Oxford University Press; 2004.

    Google Scholar 

  31. Petersen RC. Mild cognitive impairment: transition between aging and Alzheimer’s disease. Neurologia. 2000;15:93–101.

    PubMed  Google Scholar 

  32. Devanand DP, Liu X, Tabert MH, Pradhaban G, Cuasay K, Bell K,et al. Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer’s disease. Biol Psychiatry. 2008;64:871–79.

    PubMed  Google Scholar 

  33. Monastero R, Mangialasche F, Camarda C, Ercolani S, Camarda R. A systematic review of neuropsychiatric symptoms in mild cognitive impairment. J Alzheimers Dis. 2009;18:11–30.

    PubMed  Google Scholar 

  34. Damasio AR, Tranel D, Damasio H. Amnesia caused by herpes simplex encephalitis, infarctions in basal forebrain, Alzheimer’s disease, and anoxia/ischemia. In: Boller F, Grafman J, editors. Handbook of neuropsychology. Amsterdam: Elsevier; 1989. p. 149–66.

    Google Scholar 

  35. Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL. Cell specific pathology isolates the hippocampal formation in Alzheimer’s disease. Science. 1984;225:1168–70.

    PubMed  Google Scholar 

  36. Jack CR, Petersen RC, Xu Y, O’Brien PC, Smith GE, Ivnik RJ, et al. Rate of medial temporal lobe atrophy in typical aging and Alzheimer’s disease. Neurology. 1998;51:993–9.

    PubMed  Google Scholar 

  37. Scott SA, DeKosky ST, Scheff SW. Volumetric atrophy of the amygdala in Alzheimer’s disease: quantitative serial reconstruction. Neurology. 1991;41:351–6.

    PubMed  Google Scholar 

  38. Whitehouse PJ, Price DL, Clark AW, Coyle JT, DeLong MR. Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus baslis. Ann Neurol. 1981;10:122–6.

    PubMed  Google Scholar 

  39. Xuereb JH, Perry RH, Candy JM, Perry EK, Marshall E, Bonham JR. Nerve cell loss in the thalamus in Alzheimer’s disease and Parkinson’s disease. Brain. 1991;114:1363–79.

    PubMed  Google Scholar 

  40. Adlam A-L, Patterson K, Bozeat S, Hodges JR. The Cambridge Semantic Memory Test Battery: detection of semantic deficits in semantic dementia and Alzheimer’s disease. Neurocase. 2010;16:193–207.

    PubMed  Google Scholar 

  41. Bozeat S, Lambon Ralph MA, Patterson K, Garrard P, Hodges JR. Non-verbal semantic impairment in semantic dementia. Neuropsychologia. 2000;38:1207–15.

    PubMed  Google Scholar 

  42. Davies RR, Halliday GM, Xuereb JH, Kril JJ, Hodges JR. The neural basis of semantic memory: evidence from semantic dementia. Neurobiol Aging. 2009;30(12):2043–52.

    PubMed  Google Scholar 

  43. Drachman DA, Leavitt J. Human memory and the cholinergic system. A relationship to aging? Arch Neurol. 1974;30:113–21.

    PubMed  Google Scholar 

  44. Womack KB, Heilman KM. Tolterodine and memory: dry but forgetful. Arch Neurol. 2003;60:771–3.

    PubMed  Google Scholar 

  45. Benson DF, Marsden CD, Meadows JC. The amnesic syndrome of posterior cerebral artery occlusion. Acta Neurol Scand. 1974;50:133–45.

    PubMed  Google Scholar 

  46. Graff-Radford NR, Tranel D, Van Hoesen GW, Brandt JP. Diencephalic amnesia. Brain. 1990;113:1–25.

    PubMed  Google Scholar 

  47. Volpe BT, Hirst W. Amnesia following the rupture and repair of an anterior communicating artery aneurysm. J Neurol Neurosurg Psychiatry. 1983;46:704–9.

    PubMed  Google Scholar 

  48. Part SA, Hahn JH, Kim JI, Na DL, Huh K. Memory deficits after bilateral anterior fornix infarction. Neurology. 2000;54:1379–82.

    PubMed  Google Scholar 

  49. Renou P, Ducreux D, Batouche F, Denier C. Pure and acute Korsakoff syndrome due to a bilateral anterior fornix infarction: A diffusion tensor tractography study. Arch Neurol. 2008;65:1252–53.

    PubMed  Google Scholar 

  50. Zola-Morgan S, Squire LR, Amaral DG. Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J Neurosci. 1986;6:2950–67.

    PubMed  Google Scholar 

  51. Squire LR, Zola SM. Ischemic brain damage and memory impairment: a commentary. Hippocampus. 1996;6(5):546–52.

    PubMed  Google Scholar 

  52. Butters N. Alcoholic Korsakoff’s syndrome: an update. Semin Neurol. 1984;4:226–44.

    Google Scholar 

  53. Butters N, Cermak LS. Alcoholic Korsakoff’s syndrome: an information processing approach to amnesia. New York: Academic; 1980.

    Google Scholar 

  54. Victor M, Adams RD, Collins GH. The Wernicke-Korsakoff Syndrome. Philadelphia: F.A. Davis Co.; 1971.

    Google Scholar 

  55. Becker JT, Furman JMR, Panisset M, Smith C. Characteristics of the memory loss of a patient with Wernicke-Korsakoff’s syndrome without alcoholism. Neuropsychologia. 1990;28:171–9.

    PubMed  Google Scholar 

  56. Newman ME, Adityanjee A, Sobolewski E, Jampala VC. Wernicke-Korsakoff amnestic syndrome secondary to malnutrition in a patient with schizoaffective disorder. Neuropsychiatry Neuropsychol Behav Neurol. 1998;11(4):241–4.

    PubMed  Google Scholar 

  57. Damasio AR, Eslinger PJ, Damasio H, Van Hoesen GW, Cornell S. Multimodal amnesic syndrome following bilateral temporal and basal forebrain damage. Arch Neurol. 1985;42:252–9.

    PubMed  Google Scholar 

  58. Cermak LS. The encoding capacity of a patient with amnesia due to encephalitis. Neuropsychologia. 1976;14(3):11–326.

    Google Scholar 

  59. Cermak LS, O’Connor M. The anterograde and retrograde retrieval ability of a patient with amnesia due to encephalitis. Neuropsychologia. 1983;21:213–34.

    PubMed  Google Scholar 

  60. Fujii T, Yamadori A, Endo K, Suzuki K, Fukatsu R. Disproportionate retrograde amnesia in a patient with herpes simplex encephalitis. Cortex. 1999;35(5):599–614.

    PubMed  Google Scholar 

  61. Tanaka Y, Miyazawa Y, Hashimoto R, Nakano I, Obayashi T. Postencephalitic focal retrograde amnesia after bilateral anterior temporal lobe damage. Neurology. 1999;53(2):344–50.

    PubMed  Google Scholar 

  62. Wainwright MS, Martin PL, Morse RP, Lacaze M, Provenzale JM, Coleman RE, Morgan MA, Hulette C, Kurtzberg J, Bushnell C, Epstein L, Lewis DV. Human herpes virus 6 limbic encephalitis after stem cell transplantation. Ann Neurol. 2001;50:612–9.

    PubMed  Google Scholar 

  63. Hokkanen L, Launes J. Neuropsychological sequelae of acute-onset sporadic viral encephalitis. Neuropsychol Rehabil. 2008;17(4–5):450–77.

    Google Scholar 

  64. Corsellis JA, Goldberg GJ, Norton AR. “Limbic encephalitis” and its association with carcinoma. Brain. 1968;91:481–96.

    PubMed  Google Scholar 

  65. Khan N, Wieser HG. Limbic encephalitis: a case report. Epilepsy Res. 1994;17(2):175–81.

    PubMed  Google Scholar 

  66. Martin RC, Haut MW, Goeta Kreisler K, Blumenthal D. Neuropsychological functioning in a patient with paraneoplastic limbic encephalitis. J Int Neuropsychol Soc. 1996;2(5):460–6.

    PubMed  Google Scholar 

  67. Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J. Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumor association in 50 patients. Brain. 2000;123:1481–94.

    PubMed  Google Scholar 

  68. Bien CG, Schulze-Bonhage A, Deckert M, Urbach H, Helmstaedter C, Grunwalt T, Schaller C, Elger CE. Limbic encephalitis not associated with neoplasm as a cause of temporal lobe epilepsy. Neurology. 2000;55:1823–8.

    PubMed  Google Scholar 

  69. Dalmau J, Bataller L. Clinical and immunological diversity of limbic encephalitis: a model for paraneoplastic neurological disorders. Hematol Oncol Clin North Am. 2006;20:1319–35.

    PubMed  Google Scholar 

  70. Darnell RB, Poser JB. Autoimmune encephalopathy (editorial). Ann Neurol. 2009;66:1–2.

    PubMed  Google Scholar 

  71. Nokura K, Yamamoto H, Okawara Y, Koga H, Osawa H, Sakai K. Reversible limbic encephalitis caused by ovarian teratoma. Acta Neurol Scand. 1997;95:367–73.

    PubMed  Google Scholar 

  72. Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, et al. Anti-NMDA-receptor encephalitis: Case series and analysis of the effects of antibodies. Lancet Neurol. 2008;7:1091–98.

    PubMed  Google Scholar 

  73. Florance NR, Davis RL, Lam C, Szperka C, Zhou L, Ahmad S, Campen CJ, Moss H, Peter N, Gleichman AJ, Glasere CA, Lynch DR, Rosenfeld MR, Dalmau J. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol. 2009;66:11–8.

    PubMed  Google Scholar 

  74. Levite M, Ganor Y. Autoantibodies to glutamate receptors can damage the brain in epilepsy, systemic lupus erythematosus and encephalitis. Expert Rev Neurother. 2008;8:1141–60.

    PubMed  Google Scholar 

  75. Levin HS. Memory deficit after closed head injury. In: Boller F, Grafman J, editors. Handbook of neuropsychology, vol. 3. Amsterdam: Elsevier; 1989. p. 183–207.

    Google Scholar 

  76. Ownsworth T, McKenna K. Investigation of factors related to employment outcome following traumatic brain injury: a critical review and conceptual model. Disabil Rehabil. 2004;26:765–83.

    PubMed  Google Scholar 

  77. Ponsford J, Draper K, Schonberger M. Functional outcome 10 years after traumatic brain injury: Its relationship with demographic, injury severity, and cognitive and emotional status. J Int Neuropsychol Soc. 2008;14:233–42.

    PubMed  Google Scholar 

  78. Ponsford JL, Olver JH, Curran C, Ng K. Prediction of employment status 2 years after traumatic brain injury. Brain Inj. 1995;9:11–20.

    PubMed  Google Scholar 

  79. Russell WR, Nathan PW. Traumatic amnesia. Brain. 1946;69:290–300.

    Google Scholar 

  80. Whitty CD, Zangwill OL, editors. Amnesia. London: Butterworths; 1977.

    Google Scholar 

  81. Vannorsdall TD, Cascella NG, Rao V, Pearlson GD, Gordon B, Schretlen DJ. A morphometric analysis of neuroanatomic abnormalities in traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2010;22:173–81.

    PubMed  Google Scholar 

  82. Caplan LB. Transient global amnesia. In: Frederiks JAM, editor. Handbook of clinical neurology, vol. 1. Amsterdam: Elsevier; 1985. p. 205–18.

    Google Scholar 

  83. Hodges JR, Warlow CP. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry. 1990;53:834–43.

    PubMed  Google Scholar 

  84. Kritchevsky M. Transient global amnesia. In: Boller F, Grafman J, editors. Handbook of neuropsychology, vol. 3. Amsterdam: Elsevier; 1989. p. 167–82.

    Google Scholar 

  85. Kritchevsky M, Squire LR, Zouzounis JA. Transient global amnesia: characterization of anterograde and retrograde amnesia. Neurology. 1988;38:213–9.

    PubMed  Google Scholar 

  86. Bilo L, Meo R, Ruosi P, de Leva MF, Striano S. Transient epileptic amnesia: an emerging late-onset epileptic syndrome. Epilepsia. 2009;50 Suppl 5:58–61.

    PubMed  Google Scholar 

  87. Fisher CM. Transient global amnesia: precipitating activities and other observations. Arch Neurol. 1982;39:605–8.

    PubMed  Google Scholar 

  88. Fisher CM, Adams RD. Transient global amnesia. Trans Am Neurol Assoc. 1958;83:143–5.

    Google Scholar 

  89. Olesen J, Jørgensen MB. Leao’s spreading depression in the hippocampus explains transient global amnesia: a hypothesis. Acta Neurol Scand. 1986;73:219–20.

    PubMed  Google Scholar 

  90. Heathfield KWG, Croft PB, Swash M. The syndrome of transient global amnesia. Brain. 1973;96:729–36.

    PubMed  Google Scholar 

  91. Shuping JR, Rollinson RD, Toole JF. Transient global amnesia. Ann Neurol. 1980;7:281–5.

    PubMed  Google Scholar 

  92. Caplan L, Chedru F, Lhermitte F, Mayman C. Transient global amnesia and migraine. Neurology. 1981;31:1167–70.

    PubMed  Google Scholar 

  93. Schmidtke K, Ehmsen L. Transient global amnesia and migraine. A case control study. European Neurol. 2008;40:9--14.

    PubMed  Google Scholar 

  94. Tosi L, Righetti CA. Transient global amnesia and migraine in young people. Clin Neurol Neurosurg. 1997;99:63–65.

    PubMed  Google Scholar 

  95. Haas DC, Ross GS. Transient global amnesia triggered by mild head trauma. Brain. 1986;109:251–7.

    PubMed  Google Scholar 

  96. Chung C-P, Hsu H-Y, Chao A-C, Chang F-C, Sheng W-Y, Hu H-H. Detection of intracranial venous reflux in patients of transient global amnesia. Neurology. 2006;66:1873–7.

    PubMed  Google Scholar 

  97. Alberici E, Pichiecchio A, Caverzasi E, Farina LM, Persico A, Cavallini A, Bastianello S. Transient global amnesia: hippocampal magnetic resonance imaging abnormalities. Funct Neurol. 2008;23:149–52.

    PubMed  Google Scholar 

  98. Ay H, Furie KL, Yamada K, Koroshetz WJ. Diffusion-weighted MRI characterizes the ischemic lesion in transient global amnesia. Neurology. 1998;51:901–3.

    PubMed  Google Scholar 

  99. Woolfenden AR, O’Brien MW, Schwartzberg RE, Norbash AM, Tong DC. Diffusion-weighted MRI in transient global amnesia precipitated by cerebral angiography. Stroke. 1997;28:2311–4.

    PubMed  Google Scholar 

  100. Bartsch T, Deuschl G. Transient global amnesia: functional anatomy and clinical implications. Lancet Neurol. 2010;9:205–14.

    PubMed  Google Scholar 

  101. Sedlaczek O, Hirsch JG, Grips E, Peters CN, Gass A, Wöhrle J, Hennerici M. Detection of delayed focal MR changes in the lateral hippocampus in transient global amnesia. Neurology. 2004;62:2165–70.

    PubMed  Google Scholar 

  102. Toledo M, Pujadas R, Grivé E, Álvarez-Sabin J, Quintana M, Rovira A. Lack of evidence for arterial ischemia in transient global amnesia. Stroke. 2008;39:476–9.

    PubMed  Google Scholar 

  103. Miller JW, Petersen RC, Metter EJ, Millikan CH, Yanagihara T. Transient global amnesia: clinical characteristics and prognosis. Neurology. 1987;37:733–7.

    PubMed  Google Scholar 

  104. Kapur N. Transient epileptic amnesia—a clinical update and reformulation. J Neurol Neurosurg Psychiatry. 1993;56:1184–90.

    PubMed  Google Scholar 

  105. Butler CR, Zeman A. A case of transient epileptic amnesia with radiological localization. Nat Clin Pract Neurol. 2008;4:516–21.

    PubMed  Google Scholar 

  106. Sackeim HA. The cognitive effects of electroconvulsive therapy. In: Moos WH, Gamzu ER, Thal LJ, editors. Cognitive disorders: pathophysiology and treatment. New York, NY: Marcel Dekker; 1992. p. 183–228.

    Google Scholar 

  107. Semkovska M, McLoughlin DM. Objective cognitive performance associated with electroconvulsive therapy for depression: a systematic review and meta-analysis. Biol Psychiatry. 2010;15:568–77.

    Google Scholar 

  108. Squire LR. A stable impairment in remote memory following electroconvulsive therapy. Neuropsycho­logia. 1975;13:51–8.

    PubMed  Google Scholar 

  109. Squire LR. ECT and memory dysfunction. In: Lerer B, Weiner RD, Belmaker RH, editors. ECT: basic mechanisms. Washington, DC: American Psychiatric Press; 1984. p. 156–63.

    Google Scholar 

  110. Squire LR, Chace PM. Memory functions six to nine months after electroconvulsive therapy. Arch Gen Psychiatry. 1975;32:1157–64.

    Google Scholar 

  111. Squire LR, Slater PC. Electroconvulsive therapy and complaints of memory dysfunction: a prospective three-year follow-up study. Br J Psychiatry. 1983;142:1–8.

    PubMed  Google Scholar 

  112. Squire LR, Chace PM, Slater PC. Retrograde amnesia following electroconvulsive therapy. Nature. 1976;260:775–77.

    PubMed  Google Scholar 

  113. Squire LR, Slater PC, Miller P. Retrograde amnesia following ECT: Long-term follow-up studies. Arch Gen Psychiatry. 1981;38:89–95.

    PubMed  Google Scholar 

  114. Eacott MJ, Crawley RA. Childhood amnesia: on answering questions about very early life events. Memory. 1999;7(3):279–92.

    PubMed  Google Scholar 

  115. Usher JA, Neisser U. Childhood amnesia and the beginnings of memory for four early life events. J Exp Psychol Gen. 1993;122(2):155–65.

    PubMed  Google Scholar 

  116. Wetzler SE, Sweeney JA. Childhood amnesia: a conceptualization in cognitive-psychological terms. J Am Psychoanal Assoc. 1986;34(3):663–85.

    PubMed  Google Scholar 

  117. Roth T, Roehrs T, Zwyghuizen Doorenbos A, Stepanski E, Wittig R. Sleep and memory. Psychopharmacol Ser. 1988;6:140–5.

    PubMed  Google Scholar 

  118. Markowitsch HJ. Functional neuroimaging correlates of functional amnesia. Memory. 1999;7(5–6):561–83.

    PubMed  Google Scholar 

  119. Kessler J, Markowitsch HJ, Huber M, Kalbe E, Weber-Luxenburger G, Kock P. Massive and persistent anterograde amnesia in the absence of detectable brain damage: anterograde psychogenic amnesia or gross reduction in sustained effort? J Clin Exp Neuropsychol. 1997;19(4):604–14.

    PubMed  Google Scholar 

  120. Kopelman MD. Amnesia: organic and psychogenic. Br J Psychiatry. 1987;150:428–42.

    PubMed  Google Scholar 

  121. Kapur N. Amnesia in relation to fugue states—distinguishing a neurological from a psychogenic basis. Br J Psychiatry. 1991;159:872–7.

    PubMed  Google Scholar 

  122. Reinhold N, Markowitsch HJ. Retrograde episodic memory and emotion: a perspective from patients with dissociative amnesia. Neuropsychologia. 2009;47:2197–206.

    PubMed  Google Scholar 

  123. Kihlstron JF, Schacter DL. Functional amnesia. In: Boller F, Grafman J, editors. Handbook of neuropsychology, vol. 2. 2nd ed. Amsterdam: Elsevier; 2000. p. 409–27.

    Google Scholar 

  124. Hodges JR, Patterson K. Semantic dementia: a unique clinicopathological syndrome. Lancet Neurol. 2007;6:1004–14.

    PubMed  Google Scholar 

  125. Warrington EK, Shallice T. Category specific semantic impairments. Brain. 1984;107:829–54.

    PubMed  Google Scholar 

  126. Capitani E, Laiacona M, Mahon B, Caramazza A. What are the facts of semantic category-specific deficits? A critical review of the clinical evidence. Cogn Neuropsychol. 2003;20:213–62.

    PubMed  Google Scholar 

  127. Farah MJ, McClelland JI. A computational model of semantic memory impairment: modality specificity and emergent category specificity. J Exp Psychol. 1991;120:339–57.

    Google Scholar 

  128. Thompson-Schill SL, Aguirre GK, D’Esposito M, Farah MJ. A neural basis for category and modality specificity of semantic knowledge. Neuropsychologia. 1999;37:671–6.

    PubMed  Google Scholar 

  129. Tippett LJ, Meier SL, Blackwood K, Diaz-Asper C. Category specific deficits in Alzheimer’s disease: fact or artifact? Cortex. 2007;43:907–20.

    PubMed  Google Scholar 

  130. Lambon Ralph MA, Lowe C, Rogers TT. Neural basis of category-specific semantic deficits: evidence from semantic dementia, HSVE, and a neural network model. Brain. 2007;130:1127–37.

    PubMed  Google Scholar 

  131. Davies RR, Kipps CM, Mitchell J, Kril JJ, Halliday GM, Hodges JR. Progression in frontotemporal dementia: identifying a benign behavioral variant by magnetic resonance imaging. Arch Neurol. 2006;63:1627–31.

    PubMed  Google Scholar 

  132. Pijnenburg YA, Gillissen F, Jonker C, Scheltens P. Initial complaints in frontotemporal lobar degeneration. Dement Geriatr Cogn Disord. 2004;17:302–6.

    PubMed  Google Scholar 

  133. Thompson SA, Patterson K, Hodges JR. Left/right asymmetry of atrophy in semantic dementia: behavioural cognitive implications. Neurology. 2003;61:1196–203.

    PubMed  Google Scholar 

  134. Hodges JR, Graham KS. Episodic memory: insights from semantic dementia. Phil Trans R Soc Lond: B Biol Sci. 2001;356:1423–34.

    Google Scholar 

  135. Altmann LJ, McClung JS. Effects of semantic impairment on language use in Alzheimer’s disease. Semin Speech Lang. 2008;29:18–31.

    PubMed  Google Scholar 

  136. Cuetos F, Herrera E, Ellis AW. Impaired word recognition in Alzheimer’s disease: the role of age of acquisition. Neuropsychologia. 2010;48:3329–34.

    PubMed  Google Scholar 

  137. Johnston RA, Barry C. Age of acquisition in semantic processing of pictures. Mem Cognit. 2005;33:905–12.

    PubMed  Google Scholar 

  138. Juhasz BJ. Age of acquisition effects in word and picture identification. Psychol Bull. 2005;131:684–712.

    PubMed  Google Scholar 

  139. Venneri A, McGeown WJ, Heitanen H, Guerrini C, Ellis AW, Shanks MF. The anatomical basis of semantic retrieval deficits in early Alzheimer’s disease. Neuropsychologia. 2008;46:497–510.

    PubMed  Google Scholar 

  140. Xie SX, Libon DJ, Wang X, Massimo L, Moore P, et al. Longitudinal patterns of semantic and episodic memory in frontotemporal lobar degeneration and Alzheimer’s disease. J Int Neuropsychol Soc. 2010;16:278–86.

    PubMed  Google Scholar 

  141. Adlam A-LR, Bozeat S, Arnold R, Watson P, Hodges JR. Semantic knowledge in mild cognitive impairment and mild Alzheimer’s disease. Cortex. 2006;42:675–84.

    PubMed  Google Scholar 

  142. Hodges JR, Patterson K. Is semantic memory consistently impaired early in the course of Alzheimer’s disease? Neuroanatomical and diagnostic implications. Neuropsychologia. 1995;33:441–59.

    PubMed  Google Scholar 

  143. Scahill VL, Hodges JR, Graham KS. Can episodic memory tasks differentiate semantic dementia from Alzheimer’s disease? Neurocase. 2005;11:441–51.

    PubMed  Google Scholar 

  144. Kopelman MD, Stanhope N, Kingsley D. Retrograde amnesia in patients with diencephalic, temporal lobe, or frontal lesions. Neuropsychologia. 1999;37:939–58.

    PubMed  Google Scholar 

  145. McCarthy RA, Warrington EK. Actors but not scripts: the dissociation of people and events in retrograde amnesia. Neuropsychologia. 1992;30(7):633–44.

    PubMed  Google Scholar 

  146. Gainotti G. What the locus of brain lesion tells us about the nature of the cognitive defect underlying category-specific disorders: a review. Cortex. 2000;36:539–59.

    PubMed  Google Scholar 

  147. Laws KR, Sartori G. Category deficits and paradoxical dissociations in Alzheimer’s disease and herpes simplex encephalitis. J Cogn Neurosci. 2005;17:1453–9.

    PubMed  Google Scholar 

  148. Noppeney U, Patterson K, Tyler LK, Moss H, Stamatakis EA, Bright P, Mummery C, Price CJ. Temporal lobe lesions and semantic impairment: a comparison of herpes simplex virus encephalitis and semantic dementia. Brain. 2007;130:1138–47.

    PubMed  Google Scholar 

  149. Capitani E, Laiacona M, Pagani R, Capasso R, Zampetti P, Miceli G. Posterior cerebral artery infarcts and semantic category dissociations: a study of 28 patients. Brain. 2009;132:965–81.

    PubMed  Google Scholar 

  150. Johnson JK, Diehl J, Mendez MF, Neuhaus J, Shapria JS, et al. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol. 2005;62:925–30.

    PubMed  Google Scholar 

  151. Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer’s disease. Neurology. 1993;43:1467–72.

    PubMed  Google Scholar 

  152. Pietrini V, Nertempi P, Vaglia A, Revello MG, Pinna V, Ferro-Milone F. Recovery from herpes simplex encephalitis: selective impairment of specific semantic categories with neuroradiological correlation. J Neurol Neurosurg Psychiatry. 1988;51:1284–93.

    PubMed  Google Scholar 

  153. Bird CM, Chan D, Hartley T, Pijnenburg YA, Rossor MN, Burgess N. Topographical short-term memory differentiates Alzheimer’s disease from frontotemporal lobar degeneration. Hippocampus. 2010;20:1154–69.

    PubMed  Google Scholar 

  154. Kramer J, Jurik J, Sha S. Distinctive neuropsychological pattern in frontotemporal dementia, semantic dementia, and Alzheimer’s disease. Cogn Behav Neurol. 2003;16:211–8.

    PubMed  Google Scholar 

  155. Hodges JR, Patterson K, Ward R, Garrard P, Bak T, Perry R, Gregory C. The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer’s disease: a comparative neuropsychological study. Neuropsychol. 1999;13:31--40.

    PubMed  Google Scholar 

  156. Kopelman MD, Wilson BA, Baddeley A. Autobiographical memory interview. Oxford: Pearson Assessments; 1990.

    Google Scholar 

  157. Squire LR, Slater PC. Forgetting in very long term memory as assessed by an improved questionnaire technique. J Exp Psychol. 1975;104:50–4.

    Google Scholar 

  158. Seelaar H, Rohrer JD, Pijnenburg YAL, Fox NC, van Swieten JC. Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review. J Neurol Neurosurg Psychiatry. 2010. doi:10.1136/jnnp. 2010.212225.

    Google Scholar 

  159. Wechsler D, Holdnack JA, Drozdick LW. Wechsler Memory Scale, fourth edition. Technical and interpretive manual. San Antonio, TX: Pearson Assessments; 2009.

    Google Scholar 

  160. Benedict RHB, Schretlen D, Groninger L, Brandt J. Hopkins Verbal Learning Test-Revised: Normative data and analysis of inter-form and test-retest reliability. Clin Neuropsychol. 1998;12:43–55.

    Google Scholar 

  161. Delis DC, Kramer JH, Kaplan E, Ober BA. California Verbal Learning Test—second edition (CVLT-II). San Antonio, TX: Psychological Corporation; 2000.

    Google Scholar 

  162. Schmidt M. Rey Auditory and Verbal Learning Test: a handbook. Los Angeles: Western Psychological Services; 1996.

    Google Scholar 

  163. Meyers JE, Meyers KR. Rey Complex Figure Test and Recognition Trial. Odessa, FL: Psychological Assessment Resources; 1995.

    Google Scholar 

  164. Benedict R. Brief Visuospatial Memory Test-Revised professional manual. Odessa, FL: Psychological Assessment Resources, Inc.; 1997.

    Google Scholar 

  165. Trahan DE, Larrabee GJ. Continuous Visual Memory Test. Odessa, FL: Psychological Assessment Resources; 1988.

    Google Scholar 

  166. Wilson AB, Shiel A, Foley J, Smslie H, Groot Y, Hawkins K, Watson P. Cambridge Test of Prospective Memory (CAMPROMPT). San Antonio, TX: Pearson Assessments; 2005.

    Google Scholar 

  167. Crovitz HF, Schiffman H. Frequency of episodic memories as a function of their age. Bull Psychonom Soc. 1974;4:517–8.

    Google Scholar 

  168. Wechsler D, Coalson DL, Raiford SE. Wechsler Adult Intelligence Test: fourth edition technical and interpretive manual. San Antonio: Pearson Assessments; 2008.

    Google Scholar 

  169. Kertesz A. Western aphasia battery-revised. San Antonio, TX: Pearson Assessments; 2006.

    Google Scholar 

  170. Goodglass H, Kaplan E, Barresi B. Boston Diagnostic Aphasia Examination. 3rd ed. San Antonio, TX: Pearson Assessments; 2000.

    Google Scholar 

  171. Benton AL, Hamsher K deS, Sivan A. Multilingual Aphasia Examination. 3rd ed. Iowa City, IA: AJA Associates; 1994.

    Google Scholar 

  172. Delis DC, Kaplan E, Kramer J. Delis-Kaplan Executive Function Scale. San Antonio: Psychological Corporation; 2001.

    Google Scholar 

  173. Bishop D. Test for the reception of grammar—second edition (TROG-2). Sydney, AU: Pearson Assessments; 2003.

    Google Scholar 

  174. Grant DA, Berg EA. A behavioral analysis of the degree of reinforcement and ease of shifting to new responses in a Weigl-type card sorting problem. J Exp Psychol. 1948;38:404–11.

    PubMed  Google Scholar 

  175. DeFilippis NA, McCampbell E. Booklet Category Test. 2nd ed. Odessa, FL: Psychological Assessment Resources; 1997.

    Google Scholar 

  176. Stroop JR. Studies of interference in serial verbal reactions. J Exp Psychol. 1935;18:643–62.

    Google Scholar 

  177. Luria AR. Higher cortical functions in Man. New York: Basic Books; 1966.

    Google Scholar 

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Kuhn, T., Bauer, R.M. (2013). Episodic and Semantic Memory Disorders. In: Ravdin, L., Katzen, H. (eds) Handbook on the Neuropsychology of Aging and Dementia. Clinical Handbooks in Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3106-0_25

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