Antiretroviral Drugs During Breastfeeding for the Prevention of Postnatal Transmission of HIV-1

  • Athena P. Kourtis
  • Isabelle de Vincenzi
  • Denise J. Jamieson
  • Marc Bulterys
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 743)


The global pediatric human immunodeficiency virus (HIV) type 1 epidemic is fueled to a large extent by postnatal transmission from mother to infant through breastfeeding. As many as 90% of the estimated 430,000 new HIV infections in children less than 15 years of age in 2008 were due to mother-to-child transmission (MTCT) [1]. MTCT can occur in utero, intrapartum, or postpartum through breastfeeding; among children with known timing of infection, as much as 30–40% of MTCT of HIV-1 is attributable to breastfeeding; this proportion may be even higher in settings where effective interventions that decrease in utero and intrapartum transmission are being implemented [2–4].


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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Athena P. Kourtis
    • 1
  • Isabelle de Vincenzi
    • 2
  • Denise J. Jamieson
    • 1
  • Marc Bulterys
    • 3
    • 4
    • 5
  1. 1.Division of Reproductive HealthNCCDPHP, Centers for Disease Control and PreventionAtlantaUSA
  2. 2.World Health OrganizationGenevaSwitzerland
  3. 3.Division of Global HIV/AIDS (DGHA)Center for Global Health, Centers for Disease Control and Prevention (CDC)AtlantaUSA
  4. 4.CDC Global AIDS ProgramBeijingChina
  5. 5.UCLA School of Public HealthLos AngelesUSA

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